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[Equine herpesvirus 2: A study on the relation between viral excretion and respiratory disease in thoroughbred horses].

Abstract: Equine herpesvirus 2 (EHV-2) was isolated from healthy animals; therefore, the association between EHV-2 infection and respiratory disease raises the question of the role of this agent in this pathology. To date, there are no reports that relate viral excretion to health, this study then analysed 153 nasal swabs from horses in different age groups (older and younger than 1 year old) and state of health (clinically healthy and with respiratory symptoms). Results showed that the percentage of horses with viral excretion was higher within the clinically healthy group, being significative (p < 0.05) in the younger than 1 year old group, whereas the percentage of animals with respiratory symptoms did not show significant differences (p > 0.05) between age groups.
Publication Date: 2007-03-21 PubMed ID: 17370575
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  • English Abstract
  • Journal Article

Summary

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The research studies the relationship between Equine herpesvirus 2 (EHV-2) excretion and respiratory disease in thoroughbred horses. It suggests that a higher percentage of healthy horses, especially those younger than one year, show viral excretion, while animals with respiratory symptoms do not show significant differences across age groups.

Understanding the Study

The research aimed to provide insights into the correlation between Equine Herpesvirus 2 (EHV-2) excretion and respiratory disease in thoroughbred horses. This study is significant because there has been a lack of previous reports that link viral excretion to health in horses.

  • The team collected a total of 153 nasal swabs from horses, these horses fell into different categories based on their age (either older or younger than 1 year) and their state of health (either clinically healthy or exhibiting respiratory symptoms).
  • The isolated samples were then analyzed and compared according to these categories.

Results of the Study

The findings of the research were illustrative, uncovering a somewhat counterintuitive correlation between EHV-2 excretion and the horses’ health.

  • The research found that the percentage of horses excreting the virus was greater within the clinically healthy group than in the group with respiratory symptoms. This was statistically significant (p < 0.05), particularly in the sub-group of horses younger than 1 year old.
  • In contrast, the research found that there were no significant differences (p > 0.05) in viral excretion between different age groups in horses with respiratory symptoms. This suggests that age does not influence viral excretion amongst sick horses and questions the role of the EHV-2 in respiratory disease among horses.

Interpretation of the Findings

These findings suggest that healthy horses, especially young ones, may carry and shed the virus without showing symptoms of disease. The absence of a significant difference in levels of viral excretion amongst horses with respiratory symptoms, irrespective of age group, questions the role of EHV-2 as a causative agent for respiratory disease.

  • This study informs future research direction by suggesting the need for further investigation into the correlation between EHV-2 viral excretion and the manifestation of respiratory symptoms in horses. More comprehensive studies could offer further insights into the role of this virus in equine respiratory health.
  • These results could also have significant implications in veterinary medicine, particularly in handling and managing EHV-2 within healthy horse populations and determining necessary treatment measures for horses with respiratory diseases.

Cite This Article

APA
Craig MI, Barrandeguy ME, Fernández FM. (2007). [Equine herpesvirus 2: A study on the relation between viral excretion and respiratory disease in thoroughbred horses]. Rev Argent Microbiol, 38(4), 216-218.

Publication

ISSN: 0325-7541
NlmUniqueID: 8002834
Country: Argentina
Language: spa
Volume: 38
Issue: 4
Pages: 216-218

Researcher Affiliations

Craig, M I
  • Instituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas-INTA, CC25 (1712) Castelar, Pcia. de Buenos Aires, Argentina. bcraig@cicv.inta.gov.ar
Barrandeguy, M E
    Fernández, F M

      MeSH Terms

      • Age Factors
      • Animals
      • Antibodies, Viral / blood
      • Argentina / epidemiology
      • Herpesviridae Infections / epidemiology
      • Herpesviridae Infections / veterinary
      • Herpesviridae Infections / virology
      • Horse Diseases / epidemiology
      • Horse Diseases / virology
      • Horses
      • Nasal Cavity / virology
      • Respiratory Tract Infections / epidemiology
      • Respiratory Tract Infections / veterinary
      • Respiratory Tract Infections / virology
      • Rhadinovirus / immunology
      • Rhadinovirus / pathogenicity
      • Rhadinovirus / physiology
      • Tumor Virus Infections / epidemiology
      • Tumor Virus Infections / veterinary
      • Tumor Virus Infections / virology
      • Virus Replication

      Citations

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