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[Equine leukaemic lymphoma–a rare form of equine lymphoma].

Abstract: Equine leukaemic lymphoma is a rare disease of the haematopoetic tissue. It results from neoplastic degradation of B- and T-lymphocytes and their occurrence in the blood. Clinical signs are often unspecific and include chronic weight loss, ventral oedema at the thorax and abdomen and regional lymphadenopathy. Horses are often presented late in the course of the disease and therapy is rarely successful. This review summarizes the clinical pathologic findings of equine leukaemic lymphoma and the findings of laboratory testing and other diagnostic measures, and presents treatment options described in the literature.
Publication Date: 2014-10-21 PubMed ID: 25327154
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Summary

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This research article discusses Equine leukaemic lymphoma, a rare blood disease in horses, delving into its clinical signs, laboratory testing, diagnostics, and possible treatment options.

Overview of Equine Leukaemic Lymphoma

  • Equine leukaemic lymphoma is a serious disease affecting the blood-making tissues in horses. It is characterized by the abnormal growth and development of B- and T-lymphocytes in the blood. This condition is relatively rare and often results in severe health issues in the affected animals.

Signs and Symptoms

  • The clinical symptoms of this disease are often hard to identify because they’re usually not specific. They include chronic weight loss, swelling around the chest and belly due to fluid accumulation (ventral edema), and enlargement of the regional lymph nodes (lymphadenopathy).
  • Unfortunately, due to the vague and unspecific nature of these symptoms, most horses are brought in for diagnosis and treatment at the later stages of the disease when the effectiveness of the therapy is significantly reduced.

Laboratory Testing and Diagnosis

  • The article discusses the various findings of laboratory testing and other diagnostic measures used in the identification and assessment of this rare form of lymphoma. Laboratory tests generally help determine the presence of abnormal B- and T- lymphocytes in the blood, thus pointing towards a possible diagnosis of Leukaemic lymphoma.

Treatment Options

  • The research paper also presents various treatment options described in existing literature given the rarity of successful interventions. Because many horses are typically presented late in the course of this disease, there is often little hope of achieving a positive outcome from the treatment.

Conclusion

  • The authors conclude by summarizing the clinical and pathological findings of equine leukaemic lymphoma. The paper provides an essential in-depth look into this rare type of lymphoma in horses, from its clinical signs and symptoms to its diagnostic measures and potential treatments, all of which contribute to a better understanding of this serious disease.

Cite This Article

APA
Winter J, Kershaw O, Schmitz R, Gehlen H. (2014). [Equine leukaemic lymphoma–a rare form of equine lymphoma]. Tierarztl Prax Ausg G Grosstiere Nutztiere, 42(5), 311-317.

Publication

ISSN: 2567-5834
NlmUniqueID: 9715779
Country: Germany
Language: ger
Volume: 42
Issue: 5
Pages: 311-317

Researcher Affiliations

Winter, J
  • Dr. Judith Winter, Klinik für Pferde, Allgemeine Chirurgie und Radiologie, Fachbereich Veterinärmedizin, Freie Universität Berlin, Oertzenweg 19b, 14163 Berlin, E-Mail: judith.winter@fu-berlin.de.
Kershaw, O
    Schmitz, R
      Gehlen, H

        MeSH Terms

        • Animals
        • Horse Diseases / diagnostic imaging
        • Horse Diseases / pathology
        • Horses
        • Leukemia / diagnostic imaging
        • Leukemia / pathology
        • Leukemia / veterinary
        • Lymphoma / diagnostic imaging
        • Lymphoma / pathology
        • Lymphoma / veterinary
        • Ultrasonography

        Citations

        This article has been cited 1 times.
        1. Drozdzewska K, Gehlen H. Markers for internal neoplasia in the horse. Vet Med Sci 2023 Jan;9(1):132-143.
          doi: 10.1002/vms3.1042pubmed: 36495211google scholar: lookup