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Tijdschrift voor diergeneeskunde2001; 126(10); 346-351;

[Equine protozoal myeloencephalitis in the Netherlands? An overview].

Abstract: Equine protozoal myeloencephalitis (EPM) was diagnosed in a Dutch Warmblood gelding a few months after its export to the United States. The horse came back and was treated here. Additionally, an overview of the disease complex 'EPM' is given. Mode of infection, diagnosis of disease and its differential diagnoses, and general therapeutic options are presented. Although EPM due to infection with Sarcocystis neurona in Europe seems restricted to those horses that return or are imported from North America, the possibility of future cases of EPM caused by an infection with Neospora spp. is briefly discussed.
Publication Date: 2001-06-08 PubMed ID: 11392988
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Summary

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This research describes a case of Equine protozoal myeloencephalitis (EPM) in a Dutch Warmblood horse returning from the US. It outlines the disease’s mode of infection, diagnosis, treatment, and potential threats within European horses.

Disease Overview and Case Presentation

  • The study presents a case of Equine protozoal myeloencephalitis (EPM) in the Netherlands in a Dutch Warmblood gelding. This is a neurological disease in horses caused by the protozoa Sarcocystis neurona or Neospora hughesi.
  • The horse was diagnosed with EPM a few months after being exported to the United States. After returning to the Netherlands, the horse was treated for the disease.

Mode of Infection

  • The article discusses the mode of EPM infection, which is usually transmitted through ingestion. This typically happens when horses ingest feed or water contaminated with the protozoa, often through the feces of infected animals, such as opossums.
  • An infection occurs when the protozoa enter the central nervous system, causing inflammation and damage to the brain and spinal cord, which ultimately leads to neurological symptoms.

Disease Diagnosis and Therapeutic Options

  • For the diagnosis of EPM, several methods are available. These include observing clinical signs such as loss of coordination or muscle weakness, serum and cerebrospinal fluid testing for antibodies against the parasitic protozoa, and post-mortem examination to confirm the presence of the pathogen in the brain or spinal cord.
  • The treatment options generally consist of antiprotozoal drugs to kill the parasite and anti-inflammatory medications to reduce inflammation and improve neurological function. Early detection is crucial for a more effective treatment.

Assessment of Potential Threats in Europe

  • EPM infection due to Sarcocystis neurona in Europe is thought to be restricted to horses that return or are imported from North America.
  • However, the study brings forth the possible threat of cases of EPM caused by an infection with Neospora spp, even though this topic is only briefly discussed. Therefore, they suggest vigilance in monitoring horses for symptoms of EPM, especially those traveling from or to areas where the disease is prevalent.

Cite This Article

APA
Goehring LS, Sloet van Oldruitenborgh-Oosterbaan MM. (2001). [Equine protozoal myeloencephalitis in the Netherlands? An overview]. Tijdschr Diergeneeskd, 126(10), 346-351.

Publication

ISSN: 0040-7453
NlmUniqueID: 0031550
Country: Netherlands
Language: dut
Volume: 126
Issue: 10
Pages: 346-351

Researcher Affiliations

Goehring, L S
  • Hoofdafdeling Gezondheidszorg Paard, Discipline Inwendige Ziekten, Faculteit der Diergeneeskunde, Yalelaan 12-16, 3584 CM Utrecht. l.goehring@vet.uu.nl
Sloet van Oldruitenborgh-Oosterbaan, M M

    MeSH Terms

    • Animals
    • Diagnosis, Differential
    • Disease Reservoirs / veterinary
    • Encephalomyelitis / diagnosis
    • Encephalomyelitis / epidemiology
    • Encephalomyelitis / parasitology
    • Encephalomyelitis / therapy
    • Encephalomyelitis / veterinary
    • Horse Diseases / diagnosis
    • Horse Diseases / epidemiology
    • Horse Diseases / parasitology
    • Horse Diseases / therapy
    • Horses
    • Male
    • Neospora / isolation & purification
    • Netherlands / epidemiology
    • Opossums
    • Protozoan Infections, Animal / diagnosis
    • Protozoan Infections, Animal / epidemiology
    • Protozoan Infections, Animal / therapy
    • Sarcocystis / isolation & purification
    • United States / epidemiology

    References

    This article includes 34 references

    Citations

    This article has been cited 1 times.
    1. Szklarz M, Lipinska A, Slowikowska M, Niedzwiedz A, Marycz K, Janeczek M. Comparison of the clinical and radiographic appearance of the cervical vertebrae with histological and anatomical findings in an eight-month old warmblood stallion suffering from cervical vertebral stenotic myelopathy (CVSM). BMC Vet Res 2019 Aug 15;15(1):296.
      doi: 10.1186/s12917-019-2047-xpubmed: 31416466google scholar: lookup