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Diabetes technology & therapeutics2006; 7(6); 885-895; doi: 10.1089/dia.2005.7.885

Evaluation of a continuous glucose monitoring system for use in veterinary medicine.

Abstract: With the emergence of continuous glucose monitoring systems being used to provide a detailed glucose picture in humans, a commercially available system (CGMS(R), Medtronic Minimed, Northridge, CA) was examined for use in veterinary species. Methods: Adult, clinically normal horses (n = 7), cats (n = 3), dogs (n = 4), and cows (n = 5) were studied. Cats (n = 4), dogs (n = 5), and one horse with diabetes were included in the study. Several of the normal horses, including the horse with diabetes, and one cow were subjected to an intravenous glucose tolerance test. The CGMS was attached to each animal, and the recorded interstitial glucose concentrations were compared with whole blood glucose concentrations as determined by a point-of-care glucose meter. Events such as insulin administration, feeding, travel, or administration of intravenous glucose were all noted and compared with results from the CGMS. Results: There was a positive correlation between interstitial and whole blood glucose concentrations for all the clinically normal species, those with diabetes mellitus, and those receiving intravenous glucose. Events such as feeding, glucose or insulin administration, and transport to the clinic were noted by the owner or clinician and could be identified on the graph and correlated with time of occurrence. Conclusions: Our data indicate that the use of the CGMS is valid for use in the species examined. Use of this system alleviated the need for multiple blood samples and the stress associated with obtaining those samples. This system may provide greater monitoring capabilities in patients with diabetes and promote the diagnostic and research potential of serial glucose monitoring in veterinary species.
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Publication Date: 2006-01-03 PubMed ID: 16386094DOI: 10.1089/dia.2005.7.885Google Scholar: Lookup
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  • Evaluation Study
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study investigates the applicability of a commercially available continuous glucose monitoring system (originally intended for use in humans) for various veterinary species like horses, cats, dogs, and cows including those with diabetes. The authors found a positive correlation between measured interstitial and whole blood glucose concentrations in these animals; highlighting the system’s potential to simplify glucose monitoring in animal patients and reduce the stress from traditional blood sampling methods.

Research Methodology

  • The study involved several adult and clinically normal horses, cats, dogs, and cows. In addition, a few animals with diabetes and some subjected to an intravenous glucose tolerance test were also included in the study.
  • The continuous glucose monitoring system (CGMS) was attached to each animal. This device recorded the interstitial glucose concentrations from each animal over a designated period.
  • The interstitial glucose concentration was then compared with the whole blood glucose concentration as determined through traditional point-of-care glucose meter used in veterinary medicine.
  • The effects of certain significant events on blood glucose levels, such as insulin administration, feeding, travel, or administration of intravenous glucose, were also noted to identify any corresponding changes as shown by the CGMS.

Findings

  • There was a consistent positive correlation between interstitial glucose concentrations (as determined by CGMS) and whole blood glucose concentrations for all species studied, including those with diabetes mellitus and those receiving intravenous glucose.
  • The CGMS was able to identify changes in glucose levels that coincided with significant events like feeding, glucose or insulin administration, and transport.
  • The above findings suggest that the CGMS provides accurate and reliable readings of glucose levels in these species.

Conclusions

  • The use of the CGMS was found to be valid for all the tested veterinary species, indicating that it could be a useful tool for monitoring the glucose levels in these animals in a less invasive fashion compared to the traditional blood sample method.
  • The system would not only alleviate the need for multiple blood samples and the stress associated with obtaining those samples, but may also provide greater monitoring capabilities in patients with diabetes.
  • The CGMS also signals a considerable potential to augment the diagnostic and research possibilities associated with serial glucose monitoring in veterinary species.

Cite This Article

APA
Wiedmeyer CE, Johnson PJ, Cohn LA, Meadows RL, Kerl ME, Tessman RK, Perlis J, DeClue AE. (2006). Evaluation of a continuous glucose monitoring system for use in veterinary medicine. Diabetes Technol Ther, 7(6), 885-895. https://doi.org/10.1089/dia.2005.7.885

Publication

Diabetes technology & therapeutics
ISSN: 1520-9156
NlmUniqueID: 100889084
Country: United States
Language: English
Volume: 7
Issue: 6
Pages: 885-895

Researcher Affiliations

Wiedmeyer, Charles E
  • Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA. wiedmeyer@missouri.edu
Johnson, Philip J
    Cohn, Leah A
      Meadows, Richard L
        Kerl, Marie E
          Tessman, Ronald K
            Perlis, Jonathan
              DeClue, Amy E

                MeSH Terms

                • Animals
                • Blood Glucose / analysis
                • Cats
                • Cattle
                • Diabetes Mellitus, Type 1 / blood
                • Diabetes Mellitus, Type 1 / veterinary
                • Dogs
                • Glucose Tolerance Test / veterinary
                • Horses
                • Linear Models
                • Monitoring, Ambulatory / instrumentation
                • Monitoring, Ambulatory / methods
                • Monitoring, Ambulatory / veterinary

                Citations

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