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Veterinary ophthalmology2021; 25 Suppl 1; 179-184; doi: 10.1111/vop.12881

Evaluation of equine corneal disease using ultrasound biomicroscopy.

Abstract: To describe the clinical use of ultrasound biomicroscopy (UBM) to evaluate equine corneal disease. Methods: Images were obtained using a 50-MHz probe ultrasound biomicroscopy system (Quantel Aviso) and Clear Scan® probe cover. Six horses with corneal disease were evaluated via UBM for lesion size, lesion depth, and continuity of Descemet's membrane. Horses were sedated and received auriculopalpebral nerve blocks and application of topical anesthetic prior to UBM. Results: Ultrasound biomicroscopy was easily performed in all cases. UBM evaluation of three cases of corneo-limbal squamous cell carcinoma yielded information regarding lesion depth for planning of keratectomies using fixed-depth keratomes and subsequent β-radiation therapy. Corneal depth and continuity of Descemet's membrane were determined in two horses with stromal abscesses and allowed for planning of therapeutic options. In one horse with a corneal foreign body, UBM contributed to accurate assessment of the foreign body's stromal depth, which could not be assessed during ophthalmic examination due to extensive corneal cellular infiltrate. The information regarding corneal depth allowed for more accurate pre-surgical planning in patients with opaque corneal lesions. Conclusions: Ultrasound biomicroscopy was easily performed and provided useful information regarding lesion depth and continuity of Descemet's membrane for patients with corneo-limbal squamous cell carcinoma, stromal abscesses, and a corneal foreign body, allowing for increased precision in pre-surgical planning and development of therapeutic protocols.
© 2021 American College of Veterinary Ophthalmologists.
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Publication Date: 2021-03-11 PubMed ID: 33694251DOI: 10.1111/vop.12881Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study explores the usefulness of ultrasound biomicroscopy (UBM) in examining corneal disease in horses. The research points out that UBM effectively assesses lesion size, depth, and the condition of an important eye layer, thereby informing better pre-surgical decisions and treatment strategies.

Research Methodology

  • The research was carried out using a 50-MHz probe ultrasound biomicroscopy system (Quantel Aviso) and Clear Scan probe cover.
  • Six horses diagnosed with corneal diseases were included as subjects in the study.
  • The horses were sedated and given auriculopalpebral nerve blocks, and topical anesthetic prior to UBM.
  • Through UBM, researchers assessed corneal disease based on lesion size, depth, and the continuity of Descemet’s membrane (a thin layer of the cornea).

Research Findings

  • Based on the research, UBM was simple to implement in all of the cases.
  • For three cases of corneo-limbal squamous cell carcinoma (a common type of corneal cancer in horses), UBM provided significant details about the lesion depth, which assisted in the planning of keratectomies (removal of part of the cornea) and subsequent β-radiation therapy.
  • In two horses with stromal abscesses (an accumulation of pus in the corneal layer), UBM confirmed the depth of the corneal disease and the condition of the Descemet’s membrane, which in turn guided therapy selection.
  • In a case involving a horse with a corneal foreign body, UBM provided an accurate assessment of the foreign body’s depth within the stroma, which was not initially possible due to an extensive corneal cellular infiltrate (spread of cells within the cornea). This allowed for improved pre-operation planning.

Conclusion

  • The research concludes that UBM can be easily performed and offers beneficial information for assessing corneal disease in horses.
  • The technology assists in determining lesion depth and the state of the Descemet’s membrane, providing more certainty when planning pre-surgical procedures and determining therapeutic approaches.
  • The study suggests that UBM can be a vital tool in diagnosing and treating corneal diseases in equine patients more effectively.

Cite This Article

APA
Keenan AV, Townsend WM. (2021). Evaluation of equine corneal disease using ultrasound biomicroscopy. Vet Ophthalmol, 25 Suppl 1, 179-184. https://doi.org/10.1111/vop.12881

Publication

Veterinary ophthalmology
ISSN: 1463-5224
NlmUniqueID: 100887377
Country: England
Language: English
Volume: 25 Suppl 1
Pages: 179-184

Researcher Affiliations

Keenan, Alessandra V
  • Department of Clinical Sciences, Auburn University College of Veterinary Medicine, Auburn, AL, USA.
Townsend, Wendy M
  • Department of Veterinary Clinical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN, USA.

MeSH Terms

  • Abscess / veterinary
  • Animals
  • Carcinoma, Squamous Cell / veterinary
  • Corneal Diseases / diagnostic imaging
  • Corneal Diseases / pathology
  • Corneal Diseases / veterinary
  • Foreign Bodies / veterinary
  • Horse Diseases / diagnostic imaging
  • Horse Diseases / pathology
  • Horses
  • Microscopy, Acoustic / veterinary
  • Ultrasonography

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This article includes 18 references
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Citations

This article has been cited 2 times.
  1. Knickelbein KE, Lassaline ME, Kim S, Thomasy SM. Ultrasound biomicroscopy of the equine iridocorneal angle. Equine Vet J 2022 Nov;54(6):1153-1158.
    doi: 10.1111/evj.13585pubmed: 35568989google scholar: lookup
  2. Knickelbein KE, Lassaline ME, Kim S, Scharbrough MS, Thomasy SM. Corneal thickness and anterior chamber depth of the normal adult horse as measured by ultrasound biomicroscopy. Vet Ophthalmol 2022 May;25 Suppl 1(Suppl 1):17-24.
    doi: 10.1111/vop.12971pubmed: 35084084google scholar: lookup
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