Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Evaluation of exclusive use of ivermectin vs alternation of antiparasitic compounds for control of internal parasites of horses.
Abstract: A study for about a 30-month period was done to compare strongyle control programs, using per os treatments of ivermectin (IVE) paste exclusively or alternation of 4 antiparasitic paste compounds: IVE, oxfendazole (OFZ), oxibendazole (OBZ), or pyrantel pamoate (PRT). Every 8 weeks, 1 group of horses (barn C; n = 14 to 16) was given IVE paste exclusively, and a second group (barn E; n = 16) was given the 4 antiparasitic pastes on an alternating schedule. Worm eggs and larvae per gram of feces (epg and lpg, respectively) values were determined every 2 weeks during the investigation. This study in grazing horses (mares and fillies), naturally infected with internal parasites, was conducted during the period between Oct 22, 1987 and Feb 8, 1990, with an additional observation on Mar 28, 1990. For barn-C horses, treated exclusively with IVE (200 micrograms/kg of body weight) 14 times, 2-week posttreatment mean strongyle epg and lpg (small strongyle) values were reduced 99 to 100%. Mean strongyle epg and lpg (small strongyle) values for each 2-week sample period remained low (less than 20) throughout the study period, except for 1 moderate transient increase in July 1988. For the entire study period, the aggregate mean strongyle epg value was 12 and the lpg value was 6. Two-week posttreatment mean strongyle epg and lpg (small strongyle) values for barn-E horses, treated alternately with therapeutic (approx) dosage of IVE (200 micrograms/kg; 4 times), OFZ (10 mg/kg; 5 times), OBZ (10 mg/kg; 4 times), or PRT (6.6 mg base/kg; 2 times), varied within and between compounds.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1992-01-01 PubMed ID: 1539922 The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Comparative Study
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research paper examines the efficiencies of two different strategies for controlling internal parasites in horses: using only ivermectin paste, or rotating between four different antiparasitic compounds. The study was conducted over about two and a half years and involved regular fecal tests for parasite eggs and larvae. Both methods successfully reduced parasite levels, but further comparison details were not included in the abstract.
Research Context
- The study’s focus is on controlling internal parasites in horses, a significant issue in equine health management.
- Two strategies are compared: one where only ivermectin (IVE) paste is used, and another where four antiparasitic pastes—ivermectin, oxfendazole (OFZ), oxibendazole (OBZ), and pyrantel pamoate (PRT)—are alternated.
- In this study, one group of horses was administered with the IVE paste whereas another group was treated with the four mentioned antiparasitic pastes on an interchange basis.
Method of Study
- The research spanned over 30 months starting from October 22, 1987, and ending on February 8, 1990.
- The horses were treated every eight weeks during the study duration.
- The effectiveness of the treatments was determined by checking the eggs and larvae per gram of feces every two weeks.
- Additional observations were also made on March 28, 1990.
Results
- After being treated with IVE 14 times, the horses in barn C showed 99 to 100% reduction in the mean strongyle eggs and larvae.
- The mean strongyle eggs and larvae remained low throughout the study, with one moderate increase noticed in July 1988.
- For the horses in barn E, which were treated alternately with the four different antiparasitic pastes, the results varied within and between compounds.
- The entire study showed an aggregate mean strongyle eggs value of 12 and larvae value of 6.
Conclusion
- The research hints towards both strategies being effective in reducing parasite levels in horses, but a clear comparative conclusion between the two methods is not indicated in the abstract.
Cite This Article
APA
Lyons ET, Drudge JH, Tolliver SC, Granstrom DE, Stamper S.
(1992).
Evaluation of exclusive use of ivermectin vs alternation of antiparasitic compounds for control of internal parasites of horses.
Am J Vet Res, 53(1), 97-104.
Publication
Researcher Affiliations
- Department of Veterinary Science, University of Kentucky, Lexington 40546-0099.
MeSH Terms
- Administration, Oral
- Animals
- Anthelmintics / administration & dosage
- Anthelmintics / therapeutic use
- Benzimidazoles / administration & dosage
- Benzimidazoles / therapeutic use
- Drug Therapy, Combination
- Feces / parasitology
- Female
- Horse Diseases / prevention & control
- Horses
- Intestinal Diseases, Parasitic / prevention & control
- Intestinal Diseases, Parasitic / veterinary
- Intestine, Large / parasitology
- Ivermectin / administration & dosage
- Ivermectin / therapeutic use
- Larva / isolation & purification
- Ointments
- Parasite Egg Count / veterinary
- Pyrantel Pamoate / administration & dosage
- Pyrantel Pamoate / therapeutic use
- Strongyle Infections, Equine / prevention & control
- Strongyloidea / isolation & purification
Citations
This article has been cited 3 times.- Bellaw JL, Nielsen MK. Meta-analysis of cyathostomin species-specific prevalence and relative abundance in domestic horses from 1975-2020: emphasis on geographical region and specimen collection method. Parasit Vectors 2020 Oct 12;13(1):509.
- Lyons ET, Tolliver SC, Ionita M, Lewellen A, Collins SS. Field studies indicating reduced activity of ivermectin on small strongyles in horses on a farm in Central Kentucky. Parasitol Res 2008 Jun;103(1):209-15.
- Burcáková L, Königová A, Kuzmina TA, Austin CJ, Matthews JB, Lightbody KL, Peczak NA, Syrota Y, Várady M. Equine tapeworm (Anoplocephala spp.) infection: evaluation of saliva- and serum-based antibody detection methods and risk factor analysis in Slovak horse populations. Parasitol Res 2023 Dec;122(12):3037-3052.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
