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The Veterinary record2002; 151(13); 381-383; doi: 10.1136/vr.151.13.381

Evaluation of three ancillary treatments in the management of equine grass sickness.

Abstract: Brotizolam, acetylcysteine and aloe vera gel were evaluated as ancillary treatments for 29 cases of equine grass sickness. None of the treatments had any significant beneficial effect on the survival of the horses. However, 11 of 13 horses with mild chronic grass sickness survived solely with intensive nursing care.
Publication Date: 2002-10-31 PubMed ID: 12403518DOI: 10.1136/vr.151.13.381Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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This research study aimed to evaluate the effectiveness of three different treatments—Brotizolam, acetylcysteine, and aloe vera gel—in managing equine grass sickness in horses.

Introduction

In an attempt to improve survival rates in horses suffering from equine grass sickness, this study examined the potential benefits of three ancillary treatments: Brotizolam, a potent benzodiazepine; acetylcysteine, commonly used to treat paracetamol overdose and mucous secretions in conditions like pneumonia; and aloe vera gel, known for its soothing and healing properties.

Method

  • 29 cases of equine grass sickness were chosen for the study. This is a condition that affects horses, damaging their nervous system and preventing normal gut functions.
  • Each horse was assigned one of the three treatments—Brotizolam, acetylcysteine, or aloe vera gel—as an addition to their standard care.
  • Intensive nursing care, which includes assistance with feeding, maintaining hydration, and monitoring vital signs, was provided to all the horses in the study.

Results

  • None of the ancillary treatments had any significant beneficial effect on the survival of the horses. Despite the application of these treatments, the survival rate of the equine grass sickness was not improved.
  • On the positive side, 11 out of the 13 horses diagnosed with a milder, chronic form of grass sickness survived with intensive nursing care alone, indicating that supportive care may be a crucial factor in managing this condition.

Conclusion

  • The study concluded that Brotizolam, acetylcysteine, and aloe vera gel do not offer significant benefits in improving survival rates in cases of equine grass sickness.
  • However, the role of intensive nursing care appears crucial, especially in cases with mild chronic grass sickness, highlighting the importance of supportive care in the management of equine grass sickness.

Cite This Article

APA
Fintl C, McGorum BC. (2002). Evaluation of three ancillary treatments in the management of equine grass sickness. Vet Rec, 151(13), 381-383. https://doi.org/10.1136/vr.151.13.381

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 151
Issue: 13
Pages: 381-383

Researcher Affiliations

Fintl, C
  • Department of Veterinary Clinical Studies, Easter Bush Veterinary Centre, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian.
McGorum, B C

    MeSH Terms

    • Acetylcysteine / therapeutic use
    • Aloe
    • Animals
    • Appetite / drug effects
    • Autonomic Nervous System Diseases / classification
    • Autonomic Nervous System Diseases / drug therapy
    • Autonomic Nervous System Diseases / veterinary
    • Azepines / therapeutic use
    • Horses
    • Hypnotics and Sedatives / therapeutic use
    • Severity of Illness Index

    Citations

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