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Factors influencing morbidity and outcome of equine ocular squamous cell carcinoma.
Abstract: A retrospective review of 41 cases of equine ocular squamous cell carcinoma with follow up information for 33 horses is presented. An apparent prevalence in heavy horse breeds was identified. Age and sex distribution were similar to those previously reported. High recurrence (42.4 per cent) and low metastasis (6 per cent) rates were seen. Initial tumour location, primary treatment used, or patient case history had no apparent influence on final outcome. The willingness of owners to pursue with continuous treatment correlated with a high degree of success.
Publication Date: 1987-05-01 PubMed ID: 3608956DOI: 10.1111/j.2042-3306.1987.tb01378.xGoogle Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research paper investigates the factors that impact the morbidity and outcome of equine ocular squamous cell carcinoma (eye cancer in horses) by studying 41 past cases. The study reveals breed tendency towards the disease, as well as recurrence and metastasis rates. It concludes that owner commitment to continuous treatment is crucial for successful outcomes.
Research Overview
- The research is a retrospective review, meaning it looks back at past cases to gather insights. It studied 41 cases of a specific type of eye cancer in horses, with follow-up information available for 33 of them.
- The study aimed to identify the factors affecting the morbidity (the incidence of disease) and the outcome (the result of the treatment) of equine ocular squamous cell carcinoma.
Findings: Breed Prevalence
- The researchers found an elevated prevalence of the disease in heavy horse breeds. This means that cases of this type of cancer are more common in these breeds, indicating a possible genetic predisposition towards the disease.
Findings: Age and Sex Distribution
- The age and sex distribution amongst the cases were consistent with previous reports on the disease. This finding reinforces previous knowledge and strengthens the accuracy of the research.
Findings: Recurrence and Metastasis Rates
- The study revealed high rates of disease recurrence (42.4%) and low rates of metastasis (6%). Recurrence means that the disease returned after initial treatment, while metastasis refers to the spread of cancer cells to other parts of the body.
Findings: Factors Affecting Final Outcome
- The researchers did not find any significant influence from factors such as initial tumour location, primary treatment used, or the patient’s case history on the final outcome of the disease.
Findings: Owner Commitment
- A critical finding from the study was the strong correlation between the owners’ willingness to continue treatment and the success of the outcomes. This finding suggests that owner commitment to long-term treatment significantly affects the horse’s recovery and longevity.
Cite This Article
APA
Schwink K.
(1987).
Factors influencing morbidity and outcome of equine ocular squamous cell carcinoma.
Equine Vet J, 19(3), 198-200.
https://doi.org/10.1111/j.2042-3306.1987.tb01378.x Publication
Researcher Affiliations
MeSH Terms
- Age Factors
- Animals
- Carcinoma, Squamous Cell / epidemiology
- Carcinoma, Squamous Cell / mortality
- Carcinoma, Squamous Cell / veterinary
- Eye Neoplasms / epidemiology
- Eye Neoplasms / mortality
- Eye Neoplasms / veterinary
- Female
- Follow-Up Studies
- Horse Diseases / epidemiology
- Horse Diseases / mortality
- Horses
- Male
- Recurrence
- Retrospective Studies
- Sex Factors
Citations
This article has been cited 8 times.- Crausaz M, Launois T, Smith-Fleming K, McCoy AM, Knickelbein KE, Bellone RR. DDB2 Genetic Risk Factor for Ocular Squamous Cell Carcinoma Identified in Three Additional Horse Breeds. Genes (Basel) 2020 Dec 5;11(12).
- Stein L, Sledge D, Smedley R, Kiupel M, Thaiwong T. Squamous cell carcinoma with clear cell differentiation in an equine eyelid. J Vet Diagn Invest 2019 Mar;31(2):259-262.
- Jeanes EC, Koll-Hampp S, Dawson C, Dunkel B, Tetas Pont R. Rhomboid blepharoplasty and cryotherapy for the treatment of a squamous cell carcinoma on the lower eyelid in a horse. Clin Case Rep 2019 Jan;7(1):40-46.
- Sandmeyer LS, Grahn BH. Diagnostic ophthalmology. Can Vet J 2011 Jan;52(1):88-9.
- Sandmeyer LS, Breaux CB, Grahn BH. Diagnostic ophthalmology. Squamous cell carcinoma. Can Vet J 2008 May;49(5):507-8.
- Sandmeyer LS, Panizzi L, Grahn BH. Diagnostic ophthalmology. Squamous cell carcinoma. Can Vet J 2008 Mar;49(3):309-10.
- Dagenais A, Juette T, Benoit-Biancamano MO, Vanore M. Reducing Recurrence in Equine Corneolimbal SCC: Outcomes of Adjunctive Cisplatin Biodegradable Bead Therapy. Vet Sci 2026 Jan 12;13(1).
- Quatember H, Nell B, Richter B, Rigler D, Dolezal M, Sykora S, Wallner B. Studying the Impact of the DDB2 T338M Missense Mutation on the Development of Equine Squamous Cell Carcinoma and Sarcoid. Animals (Basel) 2025 Mar 22;15(7).
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