False hyperchloraemia in a dog secondary to ingestion of horse feed supplemented with potassium bromide.
Abstract: A dog was presented for acute abdominal distension after inadvertent access to a large amount of dry dog food and possibly horse feed consisting of chaff, pony cubes and vitamin, mineral and yeast supplements. Results: A marked hyperchloraemia and decreased anion gap on blood electrolyte analysis prompted a review of the patient's history for potential ingestion of bromide. It was revealed that the horse feed was supplemented with potassium bromide. The serum bromide level was 23.6 mmol/L. The dog recovered uneventfully. Conclusions: This case report highlights the importance of knowing common interferents of chemical analysis techniques.
© 2013 The Authors. Australian Veterinary Journal © 2013 Australian Veterinary Association.
Publication Date: 2013-07-31 PubMed ID: 23889097DOI: 10.1111/avj.12079Google Scholar: Lookup
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Summary
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The research article discusses a case where a dog suffered from false hyperchloraemia (high level of chloride in the blood) due to ingesting horse feed supplemented with potassium bromide.
Case Presentation
- The paper begins by discussing a particular case where a dog was brought to a veterinary clinic with a condition of acute abdominal distension. This was suspected to have occurred due to the dog’s ingestion of a large quantity of dry dog food and potentially some horse feed. The horse feed in question consisted of chaff, pony cubes, and vitamin, mineral, and yeast supplements.
Investigation and Diagnosis
- Upon an examination of the dog’s blood electrolyte analysis, the researchers note a significant hyperchloraemia, which is an abnormally high level of chloride in the bloodstream. This simultaneous with a decreased anion gap, meaning the difference between the measured cations and anions in the serum, plasma or urine was less than normal.
- This combination of results led the researchers to probe deeper into the patient’s history and look out for any potential ingestion of bromide. Bromide is known to interfere with the chloride measurements, leading to false indications of hyperchloraemia.
- Upon investigation, it was revealed that there was indeed a presence of potassium bromide in the horse feed eaten by the dog. The recorded serum bromide level for the dog stood at 23.6 mmol/L, which was quite high.
Recovery and Conclusions
- The dog in question managed to recover without any complications. This case serves as a critical example illustrating the importance of taking into account common interferents of chemical analysis techniques, like bromide in this case.
- Such analysis can greatly help in diagnosing the condition at hand appropriately and administering the correct treatment plan, thus ensuring the animal’s swift recovery.
Cite This Article
APA
Peacock RE, Smart L.
(2013).
False hyperchloraemia in a dog secondary to ingestion of horse feed supplemented with potassium bromide.
Aust Vet J, 91(8), 320-322.
https://doi.org/10.1111/avj.12079 Publication
Researcher Affiliations
- School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia, Australia. rachel.peacock@aecvet.com.au
MeSH Terms
- Animals
- Bromides / adverse effects
- Dog Diseases / blood
- Dog Diseases / chemically induced
- Dog Diseases / diagnostic imaging
- Dog Diseases / therapy
- Dogs
- Female
- Potassium Compounds / adverse effects
- Radiography
Citations
This article has been cited 1 times.- Chemonges S. Cardiorespiratory physiological perturbations after acute smoke-induced lung injury and during extracorporeal membrane oxygenation support in sheep. F1000Res 2020;9:769.
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