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Home / Equine Research Bank / Anim Genet / Fixed nucleotide differences on the Y chromosome indicate cl...
Animal genetics2003; 34(6); 453-456; doi: 10.1046/j.0268-9146.2003.01044.x

Fixed nucleotide differences on the Y chromosome indicate clear divergence between Equus przewalskii and Equus caballus.

Abstract: The phylogenetic relationship between Equus przewalskii and E. caballus is often a matter of debate. Although these taxa have different chromosome numbers, they do not form monophyletic clades in a phylogenetic tree based on mtDNA sequences. Here we report sequence variation from five newly identified Y chromosome regions of the horse. Two fixed nucleotide differences on the Y chromosome clearly display Przewalski's horse and domestic horse as sister taxa. At both positions the Przewalski's horse haplotype shows the ancestral state, in common with the members of the zebra/ass lineage. We discuss the factors that may have led to the differences in mtDNA and Y-chromosomal observations.
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Publication Date: 2003-12-23 PubMed ID: 14687077DOI: 10.1046/j.0268-9146.2003.01044.xGoogle Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research discusses the phylogenetic relationship between two horse species, Equus przewalskii (Przewalski’s horse) and E. caballus (domestic horse) and concludes that, despite some similarities, the two species distinctly differ in their Y chromosome.

Discovery and Observation

  • The study focuses on the relationship between E. przewalskii and E. caballus. These two species of horse have often been the subject of phylogenetic debates because of their chromosome numbers and mtDNA sequences.
  • To better understand this relationship, the researchers discovered five new regions of the Y chromosome in the horse lineage.
  • These regions were analyzed to track any sequence variations.

Findings and Analysis

  • The research identified two fixed nucleotide differences on the Y chromosome, distinguishing Przewalski’s horse from the domestic horse.
  • These differences are fixed, meaning they remain constant across specimen and can be used to differentiate between species.
  • Peculiarly, it was found that at these specific positions, Przewalski’s horse haplotype presents the ancestral state, consistent with members of the zebra/ass lineage, a different branch of the horse family. It suggests Przewalski’s horse may share a more recent common ancestor with zebras and asses than with domestic horses.

Assessment and Contextualization

  • These distinct differences seen on the Y chromosome, provides evidence contradicting the assumed close relationship based on mtDNA sequences.
  • What led to this contradiction between mtDNA and Y-chromosomal observations forms a part of the debate and forms a major discussion point for the researchers.
  • The factors leading to these discrepancies are considered in the research as it’s seen to be significant to the broader understanding of the genetic ancestry and evolution of these species.

Cite This Article

APA
Wallner B, Brem G, Müller M, Achmann R. (2003). Fixed nucleotide differences on the Y chromosome indicate clear divergence between Equus przewalskii and Equus caballus. Anim Genet, 34(6), 453-456. https://doi.org/10.1046/j.0268-9146.2003.01044.x

Publication

Animal genetics
ISSN: 0268-9146
NlmUniqueID: 8605704
Country: England
Language: English
Volume: 34
Issue: 6
Pages: 453-456

Researcher Affiliations

Wallner, B
  • Institut für Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinärplatz, Wien, Austria. wallner@i122server.vu-wien.ac.at
Brem, G
    Müller, M
      Achmann, R

        MeSH Terms

        • Animals
        • Base Sequence
        • DNA, Mitochondrial / genetics
        • Genetic Variation / genetics
        • Horses / classification
        • Horses / genetics
        • Male
        • Molecular Sequence Data
        • Phylogeny
        • Probability
        • Species Specificity
        • Y Chromosome / genetics

        Citations

        This article has been cited 25 times.
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