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Home / Equine Research Bank / Vet Res Commun / Gamma Glutamyl Transferase in domestic animals.
Veterinary research communications1983; 6(2); 77-90; doi: 10.1007/BF02214900

Gamma Glutamyl Transferase in domestic animals.

Abstract: In domestic animals, Gamma Glutamyl Transferase is mainly in the kidneys, the pancreas and the intestine; its liver activity is relatively high in cows, horses, sheep and goats and very low in dogs, cats and birds. The use of plasma reference values can help to interpret the variations of serum GGT mainly in hepatobiliary diseases of cattle, sheep, goats and cholestatic disorders of dogs. Urinary GGT is a good test of kidney toxic damage.
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Publication Date: 1983-03-01 PubMed ID: 6135267DOI: 10.1007/BF02214900Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The article discusses the levels and significance of Gamma Glutamyl Transferase (GGT), an enzyme found in various organs in domestic animals including the kidneys, pancreas and intestine, and its potential as a diagnostic marker for kidney damage and hepatic diseases.

Gamma Glutamyl Transferase in Domestic Animals

  • Gamma Glutamyl Transferase (GGT) is an enzyme that is largely found in the kidneys, pancreas, and intestine of domestic animals. Its concentration varies across different species and organs. Some animals like cows, horses, sheep, and goats exhibit relatively high GGT activity in the liver, while this is notably lower in dogs, cats, and birds.
  • The research indicates variations in the presence and activity of GGT in these animals, and it could be related to the differing metabolism and physiology amongst these species.

Diagnostic Value of GGT

  • Plasma reference values are tools used in diagnostics to interpret and understand the fluctuations in serum GGT. These values are particularly useful in identifying liver and biliary diseases in cattle, sheep, and goats.
  • High levels of GGT, especially in serum, could indicate the presence of hepatic diseases, given the considerable activity of this enzyme in the liver of the mentioned animals.

Urinary GGT for Kidney Damage Assessment

  • Urinary GGT, according to the study, is an effective diagnostic indicator of toxic kidney damage. When the kidneys suffer from toxic damage, increased GGT levels in urine may be observed due to its prevalence in renal tissues.
  • This makes urinary GGT a reliable and quick marker for kidney damage, and it could be used in veterinary medicine to monitor the kidney health of domestic animals.

In conclusion, the presence and levels of Gamma Glutamyl Transferase in various organs of domestic animals are of great importance, not just from a physiological perspective but also for its potential use in the diagnostic field. Further research in this area could enhance our understanding of animal health and disease management.

Cite This Article

APA
Braun JP, Benard P, Burgat V, Rico AG. (1983). Gamma Glutamyl Transferase in domestic animals. Vet Res Commun, 6(2), 77-90. https://doi.org/10.1007/BF02214900

Publication

Veterinary research communications
ISSN: 0165-7380
NlmUniqueID: 8100520
Country: Switzerland
Language: English
Volume: 6
Issue: 2
Pages: 77-90

Researcher Affiliations

Braun, J P
    Benard, P
      Burgat, V
        Rico, A G

          MeSH Terms

          • Age Factors
          • Animals
          • Animals, Domestic / metabolism
          • Biliary Tract Diseases / diagnosis
          • Biliary Tract Diseases / veterinary
          • Body Fluids / enzymology
          • Clinical Enzyme Tests / veterinary
          • Female
          • Liver Diseases / diagnosis
          • Liver Diseases / veterinary
          • Male
          • Species Specificity
          • Tissue Distribution
          • gamma-Glutamyltransferase / blood
          • gamma-Glutamyltransferase / metabolism

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