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The Veterinary clinics of North America. Equine practice2020; 36(2); 211-234; doi: 10.1016/j.cveq.2020.03.003

Genetic Testing in the Horse.

Abstract: Genetic testing in horses began in the 1960s, when parentage testing using blood group markers became the standard. In the 1990s, parentage testing shifted from evaluating blood groups to DNA testing. The development of genetics and genomics in both human and veterinarian medicine, along with continued technological advances in the last 2 decades, has helped unravel the causal variants for many horse traits. Genetic testing is also now possible for a variety of phenotypic and disease traits and is used to assist in breeding and clinical management decisions. This article describes the genetic tests that are currently available for horses.
Publication Date: 2020-06-10 PubMed ID: 32534857DOI: 10.1016/j.cveq.2020.03.003Google Scholar: Lookup
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Summary

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This study reviews the progression of genetic testing in horses beginning in the 1960s, its use in breeding and clinical management decisions, and the variety of genetic tests currently available for horses.

Historical Progression of Genetic Testing in Horses

  • The research explains that genetic testing in horses was first introduced in the 1960s, focusing on parentage verification using blood group markers.
  • By the 1990s, the technology had progressed and the focus shifted from blood group markers to more advanced DNA testing.
  • Furthermore, the paper discusses how the advancement of both human and veterinary medicine in the field of genetics and genomics throughout the last 20 years has greatly benefitted horse genetics.
  • With these technological advancements, researchers have been able to unravel many causal traits of horses.

Applications of Genetic Testing Today

  • Presently, the scope of genetic testing has expanded to include a variety of phenotypic and disease traits. This is a significant advancement from the original use in parentage verification.
  • Genetic testing aids in providing useful information which substantially helps in making breeding and clinical management decisions. With the availability of genetic tests, breeders can assess the risk of certain diseases, make informed breeding choices to avoid passing on unfavorable traits, and manage the overall health of their horse.
  • The paper closes by acknowledging that there is a wide variety of genetic tests available for horses presently. While it doesn’t detail the specifics of these tests, it emphasizes the broad applicability and importance of genetic testing in horses in today’s age.

Cite This Article

APA
Bellone RR, Avila F. (2020). Genetic Testing in the Horse. Vet Clin North Am Equine Pract, 36(2), 211-234. https://doi.org/10.1016/j.cveq.2020.03.003

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 36
Issue: 2
Pages: 211-234
PII: S0749-0739(20)30014-6

Researcher Affiliations

Bellone, Rebecca R
  • Department of Population Health and Reproduction Davis, CA 95616, USA; Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: rbellone@ucdavis.edu.
Avila, Felipe
  • Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.

MeSH Terms

  • Animals
  • Breeding / methods
  • Genetic Testing / veterinary
  • Horse Diseases / genetics
  • Horses / genetics

Conflict of Interest Statement

Disclosure R.R. Bellone and F. Avila are affiliated with the VGL, a genetic testing laboratory offering diagnostic tests in horses and other species.

Citations

This article has been cited 2 times.
  1. Avila F, Hughes SS, Magdesian KG, Penedo MCT, Bellone RR. Breed Distribution and Allele Frequencies of Base Coat Color, Dilution, and White Patterning Variants across 28 Horse Breeds. Genes (Basel) 2022 Sep 13;13(9).
    doi: 10.3390/genes13091641pubmed: 36140807google scholar: lookup
  2. Lewczuk D, Borowska A, Andruszkiewicz J, Bagnicka E. Comparative Analysis of the Stallion Field Performance Test at Different Training Stages and Horse Age. Animals (Basel) 2025 Nov 13;15(22).
    doi: 10.3390/ani15223289pubmed: 41301997google scholar: lookup