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Acta veterinaria Hungarica2004; 52(3); 259-265; doi: 10.1556/AVet.52.2004.3.2

Genetic variation within and relationships among five subpopulations of Slovak Thoroughbred.

Abstract: Genetic variation at six microsatellite loci was analysed for five Thoroughbred subpopulations to determine the magnitude of genetic differentiation and the genetic relationships among the subpopulations. Significant deviations from Hardy-Weinberg equilibrium were shown for a number of locus-population combinations, with all subpopulations. The genetic diversities and relationships of five Thoroughbred subpopulations were evaluated using six microsatellites recommended by the International Society of Animal Genetics (ISAG). The allele frequencies, the effective numbers of alleles, and the observed and expected heterozygosities were calculated. POPGENE v. 1.31 (Yeh et al., 1997) was used to test for deviations from the Hardy-Weinberg (H-W) equilibrium and to assign F(IS) estimates (Weir, 1990). The utility of microsatellites for evaluating genetic diversity of horses is discussed.
Publication Date: 2004-09-24 PubMed ID: 15379441DOI: 10.1556/AVet.52.2004.3.2Google Scholar: Lookup
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Summary

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The research article discusses a study conducted to analyze the genetic variations and relationships among five subpopulations of Slovak Thoroughbred horses using six microsatellite markers.

Objectives and Methodology

  • The main goal of the research was to examine the genetic diversity and relationships amongst five subpopulations of Slovak Thoroughbred horses.
  • For the purpose of this study, six microsatellite markers, which are recommended by the International Society of Animal Genetics (ISAG), were used.
  • The research used the POPGENE v. 1.31 software to test for any deviations from the Hardy-Weinberg (H-W) equilibrium and to estimate the F(IS) values. The H-W equilibrium is a principle in genetics that says the genetic variation in a population will remain constant from one generation to the next in the absence of other influences.

Findings

  • The study found significant deviations from the H-W equilibrium for several locus-population combinations across all subpopulations.
  • The effective numbers of alleles, allele frequencies, and observed and expected heterozygosities within these subpopulations were calculated as part of the study.

Significance

  • This research provides critical insights into the genetic diversity and relationships within the Slovak Thoroughbred subpopulations, which can contribute to the understanding of the overall genetic structure of these horses.
  • The study also emphasized the utility of microsatellites in assessing the genetic diversity of horses, reinforcing their significance in animal genetics research.
  • This information can aid in breeding programs, conserving genetic diversity, and preemptively identifying potential genetic problems within these horse populations.

Cite This Article

APA
Sátková-Jakabová D, Trandzík J, Hudecová-Kvasnáková L, Hegedüsová-Zetochová E, Bugarský A, Buleca J, Zöldág L, Jakab F, Fl'ak P. (2004). Genetic variation within and relationships among five subpopulations of Slovak Thoroughbred. Acta Vet Hung, 52(3), 259-265. https://doi.org/10.1556/AVet.52.2004.3.2

Publication

ISSN: 0236-6290
NlmUniqueID: 8406376
Country: Hungary
Language: English
Volume: 52
Issue: 3
Pages: 259-265

Researcher Affiliations

Sátková-Jakabová, Daniela
  • State Breeding Institute, Nitra, Slovak Republic.
Trandzík, J
    Hudecová-Kvasnáková, L'udmila
      Hegedüsová-Zetochová, Erika
        Bugarský, A
          Buleca, J
            Zöldág, L
              Jakab, F
                Fl'ak, P

                  MeSH Terms

                  • Animals
                  • Breeding
                  • Gene Frequency
                  • Genetic Markers
                  • Genetic Variation
                  • Genetics, Population
                  • Heterozygote
                  • Horses / genetics
                  • Microsatellite Repeats / genetics
                  • Polymerase Chain Reaction / veterinary
                  • Slovakia

                  Citations

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