Helicobacter equorum is highly prevalent in foals.
Abstract: Faecal samples of sixty-six 3-day- to 6-month-old foals were screened for Helicobacter equorum DNA by means of a PCR amplifying a 1074 bp fragment of the 23S rRNA gene with primers specific for this enterohepatic Helicobacter species. H. equorum DNA was demonstrated in faeces from 28.6% of the less than 1-month-old foals, while 67.8% of foals from 1 to 6 months of age tested positive. In a previous study, H. equorum was demonstrated in faeces of 0.8-7.9% of adult horses. These results indicate that the prevalence of H. equorum in horses differs with the age of the investigated horse population. The organism seems highly prevalent in foals between 1 and 6 months of age but the possible association with intestinal disease in this age group needs further investigation.
Publication Date: 2008-06-08 PubMed ID: 18619743DOI: 10.1016/j.vetmic.2008.06.004Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research study reveals a high prevalence of the bacteria Helicobacter equorum in foals, particularly those aged between 1 and 6 months.
Research Objectives and Methodology
- The researchers aimed to assess the prevalence of the bacteria Helicobacter equorum in foals aged from 3 days up to 6 months.
- For the study, faecal samples were collected from sixty-six foals which fell within the age range being studied.
- They then performed Polymerase Chain Reaction (PCR) tests on these samples. PCR tests serve to amplify targeted DNA sequences, and in this case, they were used to detect any traces of H. equorum DNA.
- The PCR tests targeted a specific 1074 bp fragment of the 23S rRNA gene, which is specific to the H. equorum species, establishing whether or not the bacteria is present in the samples.
Study Results
- Among the foals aged less than 1 month, about 28.6% tested positive for H. equorum.
- Strikingly, this rate of positive cases increased substantially among the 1 to 6-month-old foals, reaching 67.8%.
- In contrast, previous research indicates H. equorum detection in the faeces of adult horses fell within the relatively lower range of 0.8-7.9%.
Conclusion and Further Research
- The research demonstrates that the prevalence of H. equorum in horses varies depending on the age of the horses sampled.
- There seems to be a higher prevalence in younger horses, specifically foals between 1 and 6 months of age.
- However, there remains unclear whether there is an association between this high prevalence of H. equorum and any intestinal diseases in this age group of horses.
- The researchers highlight the need for further investigation to establish any potential correlations between the high prevalence of H. equorum and the occurrence of intestinal diseases in foals.
Cite This Article
APA
Moyaert H, Haesebrouck F, Dewulf J, Ducatelle R, Pasmans F.
(2008).
Helicobacter equorum is highly prevalent in foals.
Vet Microbiol, 133(1-2), 190-192.
https://doi.org/10.1016/j.vetmic.2008.06.004 Publication
Researcher Affiliations
- Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. Hilde.Moyaert@UGent.be
MeSH Terms
- Age Factors
- Animals
- Animals, Newborn
- Belgium / epidemiology
- DNA, Bacterial / chemistry
- DNA, Bacterial / genetics
- Feces / microbiology
- Gastrointestinal Diseases / epidemiology
- Gastrointestinal Diseases / microbiology
- Gastrointestinal Diseases / veterinary
- Gene Amplification
- Helicobacter / genetics
- Helicobacter / isolation & purification
- Helicobacter Infections / epidemiology
- Helicobacter Infections / microbiology
- Helicobacter Infections / veterinary
- Horse Diseases / epidemiology
- Horse Diseases / microbiology
- Horses
- Polymerase Chain Reaction / methods
- Polymerase Chain Reaction / veterinary
- Prevalence
- RNA, Ribosomal, 23S / chemistry
- RNA, Ribosomal, 23S / genetics
- Sensitivity and Specificity
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