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Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association2019; 61(1); 48-57; doi: 10.1111/vru.12825

High-field (3 Tesla) MRI of the navicular apparatus of sound horses shows good agreement to histopathology.

Abstract: Magnetic resonance imaging and the correlation to histopathological findings of the equine palmar foot of lame horses have been described previously, using 0.27 and 1.5 T systems. Compared to these, 3 T systems provide superior spatial resolution and imaging contrast. The aim of our prospective anatomic study was to characterize the imaging anatomy of the navicular region on 3 T MRI in comparison to histopathological findings. We hypothesized that 3 T MRI allows a good visualization of the entire navicular apparatus and reliable measurements of navicular cartilage and cortical bone thickness. Twenty front feet of sound horses were examined using a 3 T MRI system. For histopathological examination, sagittal tissue sections of the navicular bones and adjacent ligaments were prepared. Alterations in magnetic resonance signal were graded for each region and compared to corresponding histological slices. Overall, there was good visualization of the anatomical detail and a very good agreement between MRI and histology for compact bone and spongiosa, good agreement for the fibrocartilage and the distal sesamoidean impar ligament, but only moderate agreement for the hyaline cartilage and the collateral sesamoidean ligament. A comparative measurement of cartilage and cortical bone thickness on magnetic resonance images and histological sections was performed. In MRI, the hyaline cartilage of the articular surface appeared significantly thinner and the fibrocartilage of the flexor surface appeared significantly thicker compared to histology. Findings indicated that MRI at a field strength of 3 T allows reliable depiction of anatomic details of the navicular apparatus.
© 2019 The Authors. Veterinary Radiology & Ultrasound published by Wiley Periodicals, Inc. on behalf of American College of Veterinary Radiology.
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Publication Date: 2019-12-11 PubMed ID: 31825150DOI: 10.1111/vru.12825Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study investigates the accuracy and improved detail of 3 Tesla (T) magnetic resonance imaging (MRI) to identify foot conditions in horses, particularly the navicular region, as compared to histopathology. The research found that, aside from a moderate agreement with hyaline cartilage and the collateral sesamoidean ligament, the 3T MRI provided reliable measurements and good visualisation of the navicular apparatus.

Study Overview

  • The study aimed to evaluate the effectiveness of a 3 T MRI system in visualizing the navicular region of a horse’s foot as compared to the findings from histopathology.
  • The researchers hypothesized that the 3 T MRI would provide good visualization and accurate measurements of navicular cartilage and cortical bone thickness.
  • 20 horses’ front feet were examined using a 3 T MRI system, and the results were compared to histological findings from the same region.

Procedure and Findings

  • Magnetic resonance signals were graded for each region and compared to the corresponding histological slices.
  • Overall, the study found good visualization of the anatomical detail and a very good agreement between MRI and histology for compact bone and spongiosa.
  • There was good agreement for the fibrocartilage and the distal sesamoidean impar ligament. However, the agreement was only moderate for the hyaline cartilage and the collateral sesamoidean ligament.
  • Measurements of cartilage and cortical bone thickness on the MRI images and histological sections were compared.
  • In the MRI images, the hyaline cartilage of the articular surface appeared significantly thinner and the fibrocartilage of the flexor surface appeared significantly thicker compared to histology.

Conclusion

  • The findings support the initial hypothesis as they indicate that an MRI at a field strength of 3 T allows a reliable depiction of anatomic details of the navicular apparatus.
  • The use of a 3 T system offers superior spatial resolution and imaging contrast compared to MRI systems with lower Tesla ratings, thus proving to be a valuable tool for the examination and diagnosis of foot conditions in horses.

Cite This Article

APA
Kottmeier LK, Seehusen F, Helweg M, Rohn K, Stadler P, Hellige M. (2019). High-field (3 Tesla) MRI of the navicular apparatus of sound horses shows good agreement to histopathology. Vet Radiol Ultrasound, 61(1), 48-57. https://doi.org/10.1111/vru.12825

Publication

Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
ISSN: 1740-8261
NlmUniqueID: 9209635
Country: England
Language: English
Volume: 61
Issue: 1
Pages: 48-57

Researcher Affiliations

Kottmeier, Lena K
  • Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Seehusen, Frauke
  • Department of Pathology, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Helweg, Martin
  • Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Rohn, Karl
  • Institute for Biometry, Epidemiology, and Information Processing, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Stadler, Peter
  • Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Hellige, Maren
  • Clinic for Horses, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.

MeSH Terms

  • Animals
  • Cortical Bone / diagnostic imaging
  • Fibrocartilage / diagnostic imaging
  • Horses / anatomy & histology
  • Hyaline Cartilage / diagnostic imaging
  • Magnetic Resonance Imaging / veterinary
  • Prospective Studies
  • Tarsal Bones / anatomy & histology
  • Tarsal Bones / diagnostic imaging

References

This article includes 23 references
  1. Blunden A, Dyson SJ, Murray R, Schramme M. Histopathology in horses with chronic palmar foot pain and age-matched controls. Part 1: navicular bone and related structures.. Equine Vet J 2006;35:15-22.
    doi: 10.2746/042516406775374298google scholar: lookup
  2. Dyson SJ, Pool R, Blunden T, Murray R. The distal sesamoidean impar ligament: comparison between its appearance on magnetic resonance imaging and histology of the axial third of the ligament.. Equine Vet J 2010;42:332-339.
    doi: 10.1111/j.2042-3306.2010.00068.xgoogle scholar: lookup
  3. Busoni V, Heimann M, Trenteseaux J, Snaps F, Dondelinger RF. Magnetic resonance imaging findings in the equine deep digital flexor tendon and distal sesamoid bone in advanced navicular disease-an ex vivo study.. Vet Radiol Ultrasound 2005;46:279-286.
    doi: 10.1111/j.1740-8261.2005.00051.xgoogle scholar: lookup
  4. Murray R, Dyson SJ, Branch M, Schramme M. Validation of magnetic resonance imaging use in equine limbs.. Clin Tech Equine Pract 2007;6:26-36.
    doi: 10.1053/j.ctep.2006.11.003google scholar: lookup
  5. Murray R, Mair TS, Sherlock CE, Blunden A. Comparison of high-field and low-field magnetic resonance images of cadaver limbs of horses.. Vet Rec 2009;165:281-288.
  6. Dyson SJ, Blunden T, Murray R. Comparison between magnetic resonance imaging and histological findings in the navicular bone of horses with foot pain.. Equine Vet J 2012;44:692-698.
    doi: 10.1111/j.2042-3306.2012.00565.xgoogle scholar: lookup
  7. Murray R, Blunden T, Schramme M, Dyson SJ. How does magnetic resonance imaging represent histologic findings in the equine digit.. Vet Radiol Ultrasound 2006;47:17-31.
    doi: 10.1111/j.1740-8261.2005.00101.xgoogle scholar: lookup
  8. Murray R, Schramme M, Dyson SJ, Branch M, Blunden T. Magnetic resonance imaging characteristics of the foot in horses with palmar foot pain and control horses.. Vet Radiol Ultrasound 2006;47:1-16.
    doi: 10.1111/j.17408261.2005.00100.xgoogle scholar: lookup
  9. Cotten A, Delfaut E, Demondion X. MR imaging of the knee at 0.2 and 1.5 T: correlation with surgery.. AJR Am J Roentgenol 2000;174:1093-1097.
    doi: 10.2214/ajr.174.4.1741093google scholar: lookup
  10. Schild H. Clinical highfield MR.. Fortschr Röntgenstr 2005;177:621-631.
    doi: 10.1055/s-2005-858048google scholar: lookup
  11. Wright IM, Kidd L, Thorp BH. Gross, histological and histomorphometric features of the navicular bone and related structures in the horse.. Equine Vet J 1998;30:220-234.
    doi: 10.1111/j.2042-3306.1998.tb04491.xgoogle scholar: lookup
  12. Schramme M, Murray R, Blunden A, Dyson SJ. A comparison between MRI, pathology and radiology in 34 limbs with navicular syndrome and 25 control limbs.. Proc Am As equine Practnrs 2005;51:348-358.
  13. Schramme M, Kerekes Z, Hunter S, Nagy K, Pease A. Improved identification of the palmar fibrocartilage of the navicular bone with saline magnetic resonance bursography.. Vet Radiol Ultrasound 2009;50:606-614.
    doi: 10.1111/j.1740-8261.2009.01590.xgoogle scholar: lookup
  14. Graichen H, Jakob J, von Eisenhart-Rothe R, Englmeier K, Reiser M, Eckstein F. Validation of cartilage volume and thickness measurements in the human shoulder with quantitative magnetic resonance imaging.. Osteoarthr Cartilage 2003;11:475-482.
    doi: 10.1016/s1063-4584(03)00077-3google scholar: lookup
  15. Murray R, Branch M, Tranquille C, Woods S. Validation of magnetic resonance imaging of equine articular cartilage and subchondral bone thickness.. Am J Vet Res 2005;66:1999-2005.
    doi: 10.2460/ajvr.2005.66.1999google scholar: lookup
  16. Porter EG, Winter MD, Sheppard BJ, Berry CR, Hernandez JA. Correlation of articular cartilage thickness measurements made with magnetic resonance imaging, magnetic resonance arthrography, and computed tomographic arthrography with gross articular cartilage thickness in the equine metacarpophalangeal joint.. Vet Radiol Ultrasound 2016;57:515-525.
    doi: 10.1111/vru.12390google scholar: lookup
  17. Böck P. Romeis mikroskopische technik.. .
  18. Altman DG. Practical statistic for medical research.. .
  19. Yorke EH, Judy CE, Saveraid TC, McGowan CP, Caldwell FJ. Distal border fragments of the equine navicular bone: association between magnetic resonance imaging characteristics and clinical lameness.. Vet Radiol Ultrasound 2014;55:35-44.
    doi: 10.1111/vru.12082google scholar: lookup
  20. Hertsch BW, Steffen D. Comparative radiological and pathomorphological examinations of navicular bones with special attention being given to the sesamoidian canals-a contribution to the diagnosis of navicular diseases.. Dt Tieraerztl Wochenschr 1986;93:353-359.
  21. Eckstein F, Sittek H, Milz S. The potential of magnetic resonance imaging (MRI) for quantifying articular cartilage thickness-a methodological study.. Clin Biomech 1995;10:434-440.
    doi: 10.1016/0268-0033(95)00013-1google scholar: lookup
  22. McGibbon CA, Dupuy DE, Palmer WE, Krebs DE. Cartilage and subchondral bone thickness distribution with MR imaging.. Acad Radiol 1998;5:20-25.
    doi: 10.1016/s1076-6332(98)80007-xgoogle scholar: lookup
  23. McGibbon CA, Bencardino J, Palmer WE. Subchondral bone and cartilage thickness from MRI: effects of chemical-shift artifact.. Mag Res Mat in Physics, Biology and Med 2003;16:1-9.
    doi: 10.1007./s10334-003-0001-0google scholar: lookup

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