Horses and Zebras: complex cardiac anatomy in a patient with out-of-hospital cardiac arrest.
Abstract: This case report describes a woman presenting after out-of-hospital cardiac arrest with several cardiac anomalies, including a form fruste of Ebstein's anomaly complicated by a large tricuspid valve vegetation. On autopsy, she proved to have unstable plaques in epicardial vessels that likely caused arrhythmic sudden cardiac death, a reminder that even in the presence of rare anomalies, common things are common.
Publication Date: 2011-10-25 PubMed ID: 22022658PubMed Central: PMC3196666DOI: 10.1007/s13089-011-0059-2Google Scholar: Lookup
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Summary
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This case study examines a woman who experienced a sudden cardiac arrest outside of the hospital, and upon further investigation, was found to have a variety of cardiac abnormalities. Even with the presence of these rare abnormalities, it was ultimately determined that her sudden cardiac death was likely due to a commonly occurring issue – unstable plaques in epicardial vessels.
Research Overview
- This piece of research provides a detailed case study of a woman who presented with out-of-hospital cardiac arrest.
- Upon investigation, it was discovered that she had several cardiac anomalies, including a form fruste of Ebstein’s anomaly, which is a mild version of a usually very severe heart defect present from birth.
- This anomaly was further complicated by the presence of a large tricuspid valve vegetation – an abnormal growth on the tricuspid valve inside her heart.
- This indicates that the patient had quite a complex cardiac anatomy.
The Specific Anomalies and Their Implications
- Ebstein’s anomaly is a rare congenital heart defect that primarily affects the tricuspid valve.
- While the form fruste of Ebstein’s anomaly presents a less severe form, it still affects the proper functioning of the heart.
- The large tricuspid valve vegetation constitutes another significant complication as it can obstruct the blood flow, potentially break away and cause a stroke or other harmful effects.
- These anomalies present a considerable challenge in maintaining proper heart function, and could potentially contribute to critical cardiac events.
Likely Cause of Cardiac Arrest and Death
- Despite the presence of these rare cardiac anomalies, further examination revealed that the woman’s sudden cardiac death was most likely due to something far more common.
- This was the presence of unstable plaques in the epicardial vessels which are high-risk factors for serious cardiac events including heart attacks and sudden cardiac death.
- These plaques can rupture or break away, causing a blood clot that blocks blood flow to the heart.
Research Conclusions
- The paper concludes with a reminder that while rare anomalies can occur, it is often the most common problems that prevail.
- This suggests that in cardiology, as in other areas of medicine, doctors should remain aware of the “horses and zebras” principle: look for the common (horses) even when faced with the rare (zebras).
Cite This Article
APA
Brown SM, Miller DV, Vezina D, Dean NC, Grissom CK.
(2011).
Horses and Zebras: complex cardiac anatomy in a patient with out-of-hospital cardiac arrest.
Crit Ultrasound J, 3(1), 29-31.
https://doi.org/10.1007/s13089-011-0059-2 Publication
Researcher Affiliations
- Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Salt Lake City, UT, USA; Critical Care Echocardiography Service, Intermountain Medical Center, Salt Lake City, UT, USA; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT, USA.
Grant Funding
- K23 GM094465 / NIGMS NIH HHS
- K23 GM094465-01 / NIGMS NIH HHS
References
This article includes 6 references
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- Schwartz CJ, Gerrity RG. Anatomical pathology of sudden unexpected cardiac death.. Circulation 1975 Dec;52(6 Suppl):III18-26.
- Zebrack JS, Anderson JL. The role of inflammation and infection in the pathogenesis and evolution of coronary artery disease.. Curr Cardiol Rep 2002 Jul;4(4):278-88.
- Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P. Risk of myocardial infarction and stroke after acute infection or vaccination.. N Engl J Med 2004 Dec 16;351(25):2611-8.
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