How swimming affects plasma insulin and glucose concentration in Thoroughbreds: A pilot study.
Abstract: Low intensity exercise increases insulin-stimulated glucose uptake in skeletal muscle and decreases its plasma concentration. In this study, plasma insulin and glucose concentrations were evaluated 5min before and 5, 15, 25, 35, 45 and 60min after an IV bolus of glucose in 12 Thoroughbreds before and after 1 month of submaximal aquatraining exercise, monitored using heart rate and blood lactate. Plasma glucose concentrations were evaluated using a colorimetric enzymatic method, and plasma insulin concentrations with a solid-phase radioimmunoassay method. Pre-training plasma glucose concentrations at 15, 25 and 35min, area under the glucose curve and peak glucose concentration were significantly higher than post-training values (P<0.05). Baseline pre-training plasma insulin concentrations were significantly lower than in the post-training period, and plasma insulin was significantly higher at 45 and 60min in the pre-training period than the post-training period. These results indicate that aquatraining could improve insulin-glucose metabolism in horses.
Copyright © 2017 Elsevier Ltd. All rights reserved.
Publication Date: 2017-07-01 PubMed ID: 28911834DOI: 10.1016/j.tvjl.2017.06.006Google Scholar: Lookup
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Summary
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The paper reports a research study on how low intensity aquatic exercise impacts insulin and glucose levels in the blood of Thoroughbred horses. The findings suggest that such exercise could enhance the metabolism of insulin and glucose in horses.
Background and Objectives of the Research
- The study was executed with the aim of investigating the influence of submaximal aquatraining exercise on plasma insulin and glucose concentrations in Thoroughbred horses.
- The hypothesis was that low intensity exercise could escalate the uptake of glucose by skeletal muscles, and thus reduce its plasma concentration in these horses.
Research Methodology
- The study involved 12 Thoroughbreds, and their plasma insulin and glucose concentrations were measured five minutes before and five, 15, 25, 35, 45, and 60 minutes after being given an IV bolus of glucose.
- These measurements were taken before beginning the exercise regimen and then, after one month of performing submaximal aquatraining exercises.
- The exercising horses’ heart rate and blood lactate were monitored during the experiments.
- Plasma glucose concentrations were determined using a colorimetric enzymatic method, while plasma insulin concentrations were measured using a solid-phase radioimmunoassay method.
Key Findings of the Research
- Before training, the plasma glucose concentrations at 15, 25, and 35min, the area under the glucose curve, and peak glucose concentration were significantly higher than the post-training values.
- The baseline pre-training plasma insulin concentrations were significantly lower than in the post-training period, and plasma insulin was significantly higher at 45 and 60min in the pre-training period than the post-training period.
- The researchers deduced from this study that aquatraining could potentially improve the metabolism of insulin and glucose in Thoroughbred horses.
Cite This Article
APA
Bonelli F, Sgorbini M, Meucci V, Sighieri C, Baragli P.
(2017).
How swimming affects plasma insulin and glucose concentration in Thoroughbreds: A pilot study.
Vet J, 226, 1-3.
https://doi.org/10.1016/j.tvjl.2017.06.006 Publication
Researcher Affiliations
- Department of Veterinary Sciences, University of Pisa, via Livornese snc, San Piero a Grado, Pisa 56122, Italy.
- Department of Veterinary Sciences, University of Pisa, via Livornese snc, San Piero a Grado, Pisa 56122, Italy. Electronic address: micaela.sgorbini@unipi.it.
- Department of Veterinary Sciences, University of Pisa, via Livornese snc, San Piero a Grado, Pisa 56122, Italy.
- Department of Veterinary Sciences, University of Pisa, via Livornese snc, San Piero a Grado, Pisa 56122, Italy.
- Department of Veterinary Sciences, University of Pisa, via Livornese snc, San Piero a Grado, Pisa 56122, Italy.
MeSH Terms
- Animals
- Blood Glucose
- Glucose Tolerance Test / veterinary
- Horses / blood
- Insulin / blood
- Male
- Physical Conditioning, Animal
- Pilot Projects
- Swimming
Citations
This article has been cited 4 times.- Karikoski NP, Box JR, Mykkänen AK, Kotiranta VV, Raekallio MR. Variation in insulin response to oral sugar test in a cohort of horses throughout the year and evaluation of risk factors for insulin dysregulation. Equine Vet J 2022 Sep;54(5):905-913.
- Box JR, McGowan CM, Raekallio MR, Mykkänen AK, Carslake H, Karikoski NP. Insulin dysregulation in a population of Finnhorses and associated phenotypic markers of obesity. J Vet Intern Med 2020 Jul;34(4):1599-1605.
- Durham AE, Frank N, McGowan CM, Menzies-Gow NJ, Roelfsema E, Vervuert I, Feige K, Fey K. ECEIM consensus statement on equine metabolic syndrome. J Vet Intern Med 2019 Mar;33(2):335-349.
- Leguillette R, McCrae P, Massie S, Filho SA, Bayly W, David F. Workload and spirometry associated with untethered swimming in horses. BMC Vet Res 2024 Jul 19;20(1):327.
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