Idiopathic muscular hypertrophy of the oesophagus in the horse: a retrospective study of 31 cases.
Abstract: To present the first report of a case series concerning equine idiopathic muscular hypertrophy of the oesophagus (IMHO). Objective: To investigate the clinical and pathological features of the disorder. Methods: The medical records of 31 horses suffering from the disorder were reviewed retrospectively. In all these animals the diagnosis was confirmed at post mortem examination. Results: The median age of the affected horses was 12.5 +/- 5.6 years (range 1-26) without sex or breed predilection. Only 2 out of 31 horses showed clinical signs associated with oesophageal dysfunction, indicating that the muscular hypertrophy was rather a coincidental post mortem finding. Histology revealed thickening of the distal portion of the oesophagus mainly involving the circular layer of the tunica muscularis without fibrosis or inflammation. In 8 cases, the disorder was seen in concurrence with idiopathic hypertrophy of the tunica muscularis of various other parts of the gastrointestinal tract. Conclusions: In the majority of patients, IMHO was a coincidental finding at post mortem examination usually confined to the smooth, circular muscle layer of the tunica muscularis externa. Conclusions: Further research is necessary to study the precise effect of IMHO on oesophageal function.
Publication Date: 2004-02-06 PubMed ID: 14756371DOI: 10.2746/0425164044864697Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
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The research focuses on peculiar and excessive muscle growth in the oesophagus of horses, a condition known as “Idiopathic Muscular Hypertrophy of the Oesophagus” (IMHO). The authors analyzed medical records and post-mortem examination reports of 31 horses with this unusual condition.
Methodology
- The researchers carried out this study by examining the medical records of 31 horses that had been diagnosed with Idiopathic Muscular Hypertrophy of the Oesophagus (IMHO).
- All of these cases were confirmed with a post-mortem examination, aiding the accuracy and verity of the study.
Results
- The research found that horses of varying ages (from 1 to 26 years), regardless of breed or sex, could suffer from this issue. The median age of horses affected was 12.5 years.
- Interestingly, only two out of the thirty-one horses showcased clinical signs related to oesophageal dysfunction, leading to the conclusion that oftentimes, the muscular overgrowth is a surprise finding during the post-mortem examination.
- Upon inspection of the tissue, it was found that the distal (farthest) portion of the oesophagus was most affected by this overgrowth. It largely affected the circular layer of muscle in the oesophagus, without any noticeable sign of inflammation or fibrosis (scarring).
- In eight particular cases, this condition co-occurred with hypertrophy in other areas of the gastrointestinal tract, not just the oesophagus.
Conclusion
- Despite the occurrence of this muscular hypertrophy in horses, it was usually a coincidental finding at the time of post-mortem examination, specifically restricted to the circular smooth muscle layer in the oesophagus.
- The researchers concluded by implying that while this overgrowth may not always present noticeable symptoms during the horse’s life, its precise effects on the oesophagus’s functionality need to be further investigated.
Cite This Article
APA
Benders NA, Veldhuis Kroeze EJ, van der Kolk JH.
(2004).
Idiopathic muscular hypertrophy of the oesophagus in the horse: a retrospective study of 31 cases.
Equine Vet J, 36(1), 46-50.
https://doi.org/10.2746/0425164044864697 Publication
Researcher Affiliations
- Department of Equine Sciences, Medicine Section, Faculty of Veterinary Medicine, Utrecht University, PO Box 80.152, 3508 TD Utrecht, The Netherlands.
MeSH Terms
- Animals
- Esophageal Diseases / pathology
- Esophageal Diseases / veterinary
- Esophagus / pathology
- Female
- Horse Diseases / pathology
- Horses
- Hypertrophy / pathology
- Hypertrophy / veterinary
- Male
- Muscle, Smooth / pathology
- Retrospective Studies
Citations
This article has been cited 1 times.- Parkinson L, Kuzma C, Wuenschmann A, Mans C. Esophageal smooth muscle hypertrophy causing regurgitation in a rabbit. J Vet Med Sci 2017 Nov 17;79(11):1848-1852.
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