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The Veterinary record2021; 189(7); e240; doi: 10.1002/vetr.240

Inflammatory response of miniature horses subjected to open and half-closed orchiectomy techniques.

Abstract: This study aimed to evaluate the inflammatory response of miniature horses subjected to open and half-closed orchiectomy by physical examination, blood cell count, peritoneal fluid evaluation, total plasma protein, fibrinogen, and serum amyloid A (SAA) concentrations. Methods: Thirteen male healthy miniature horses were divided into two groups, according to the surgical approach: half-closed technique (HCT) and open technique (OT). The HCT group was subjected to ligation of the spermatic cord followed by its sharp incision, and closure of the vaginal tunic, and the OT group was only submitted to cord ligation. Prior to, and at 1, 2, 3 and 5 days after the surgery, a general and specific physical examination, blood cell counts, total plasma protein, peritoneal fluid evaluation, fibrinogen, and SAA concentrations were performed. Results: Higher postoperative perilesional oedema, rectal temperature, and fibrinogen were observed in the HCT group. Groups did not differ as to SAA concentrations. The evaluated local and systemic inflammatory profile demonstrated that, as expected, surgery resulted in inflammation in both groups. Conclusions: The group subjected to the HCT showed a more intense and lasting inflammatory response. However, despite the different postoperative inflammatory profiles, both groups presented a favourable outcome and recovery.
© 2021 British Veterinary Association.
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Publication Date: 2021-04-18 PubMed ID: 33870519DOI: 10.1002/vetr.240Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research compares the inflammatory responses in miniature horses subjected to two different orchiectomy surgical techniques – open and half-closed. Despite different postoperative inflammatory responses, the study found that both groups had a favorable outcome and recovery.

Objective and Methodology

  • The study aimed to evaluate and compare the inflammatory responses of miniature horses subjected to two types of orchiectomy (castration) surgeries – the half-closed technique (HCT) and the open technique (OT).
  • The HCT group underwent ligation of the spermatic cord, its sharp incision, and the closure of the vaginal tunic, whereas, the OT group was only submitted to cord ligation.
  • The inflammatory response was evaluated pre-surgery and at 1, 2, 3, and 5 days post-surgery using various methods such as general and specific physical examination, blood cell counts, total plasma protein, peritoneal fluid evaluation, fibrinogen, and Serum Amyloid A (SAA) concentrations.

Results

  • The results demonstrated that the group subjected to HCT showed a more intense and lasting inflammatory response.
  • These results were indicated by variables such as higher postoperative perilesional oedema (swelling), higher rectal temperature, and higher fibrinogen levels in the HCT group compared to the OT group.
  • The study, however, found no difference in the SAA concentrations between both the groups indicating that both methods caused a similar level of systemic inflammation.

Conclusions

  • Despite these differences in the local inflammatory responses, both surgical techniques resulted in a favourable outcome and recovery for the miniature horses.
  • However, this study indicates that the HCT method may cause a more intense and long-lasting local inflammatory response than the OT method.

Cite This Article

APA
de Moura Alonso J, de Melo-Neto GB, Dos Santos B, Mogollón García HD, Paim KP, Pinheiro Ferreira JC, Santos Schmidt EM, da Silva ANF, da Cunha GM, Takahira RK, Ferreira Canuto LE, Papa FO, Hussni CA. (2021). Inflammatory response of miniature horses subjected to open and half-closed orchiectomy techniques. Vet Rec, 189(7), e240. https://doi.org/10.1002/vetr.240

Publication

The Veterinary record
ISSN: 2042-7670
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 189
Issue: 7
Pages: e240

Researcher Affiliations

de Moura Alonso, Juliana
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
de Melo-Neto, Gabriel Barbosa
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Dos Santos, Bruna
  • Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Mogollón García, Henry David
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Paim, Kamila Pinheiro
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Pinheiro Ferreira, João Carlos
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Santos Schmidt, Elizabeth Moreira
  • Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
da Silva, Amanda Nogueira Ferreira
  • Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
da Cunha, Grazielly Marques
  • Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Takahira, Regina Kiomi
  • Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Ferreira Canuto, Lucas Emanuel
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Papa, Frederico Ozanam
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Hussni, Carlos Alberto
  • Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.

MeSH Terms

  • Animals
  • Female
  • Fibrinogen
  • Horse Diseases / surgery
  • Horses
  • Inflammation / veterinary
  • Male
  • Orchiectomy / veterinary
  • Serum Amyloid A Protein / analysis

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Citations

This article has been cited 1 times.
  1. Gandini M, Bertone C, Giusto G. Description and Complications of a New Modified Semi-Closed Castration Technique in Horses. Vet Sci 2025 Jul 31;12(8).
    doi: 10.3390/vetsci12080720pubmed: 40872671google scholar: lookup
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