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Home / Equine Research Bank / Vet Clin Pathol / Influence of multiple factors on hematologic reference inter...
Veterinary clinical pathology2021; 50(2); 273-277; doi: 10.1111/vcp.12965

Influence of multiple factors on hematologic reference intervals in horses residing in livery yards in Spain.

Abstract: The hemogram is a routine analysis for equine veterinary practitioners in the assessment of patient clinical status. Reference intervals (RIs) of hematologic constituents vary according to different horse populations and are often described for a particular breed or horse type. The aims of this study were to determine RIs for hematologic constituents in a mixed-breed horse population residing in livery yards in central Spain and evaluate the associations between estimated RIs and multiple phenotypic and management characteristics. A total of 122 healthy horses from different breeds in central Spain were included in the study. RIs were calculated following the American Society for Veterinary Clinical Pathology guidelines. Significant associations between red blood cell (RBC) counts, packed cell volumes (PCVs), hemoglobin (HGB) concentrations, white blood cell (WBC) counts, and phenotypic and management features were evaluated using a novel multiple linear regression model analysis. Reference intervals were 5.8-10.0 × 1012 /L for RBCs, 97-164 g/L for HGB, 0.27-0.46 L/L for PCVs, 37.1-53.6 fL for MCVs, 3.8-10.8 × 109 /L for WBCs, and 76.1-377.9 × 109 /L for platelet counts. The season, discipline, and housing when and where the horses were sampled were factors significantly associated with WBC counts and/or red cell values (HGB, RBC, and PCV). Hematologic RIs for these horses were comparable to the RIs of warm-blooded horses and influenced by husbandry. These location-specific RIs should allow veterinary practitioners to make better-informed decisions for their patients residing in livery yards.
© 2021 American Society for Veterinary Clinical Pathology.
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Publication Date: 2021-05-30 PubMed ID: 34053088DOI: 10.1111/vcp.12965Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research paper discusses the influence of several factors on the hemogram, or full blood count, in horses living in livery yards in Spain. The study aimed to determine the typical range for different blood constituents in a mixed-breed horse population and to understand how these ranges are associated with various physical and management characteristics of the horses.

Study Participants and Procedure

  • The research involved a total of 122 healthy horses of various breeds living in central Spain.
  • The American Society for Veterinary Clinical Pathology guidelines were used to calculate the reference intervals for each blood constituent.
  • The team investigated associations between the measures of red and white blood cells, packed cell volumes, and hemoglobin concentrations and various characteristics of the horses using a novel multiple linear regression model analysis.

Reference Intervals

  • The study found the following reference intervals: 5.8-10.0×10 /L for red blood cells; 97-164 g/L for hemoglobin; 0.27-0.46 L/L for packed cell volumes; 37.1-53.6 fL for mean corpuscular volumes; 3.8-10.8×10 /L for white blood cells; and 76.1-377.9×10 /L for platelet counts.

Factors Influencing Blood Constituent Levels

  • The study revealed significant associations between the counts of white blood cells and/or red blood cell values (hemoglobin, red blood cells, and packed cell volumes) and the season, discipline, and housing conditions during which the horses’ blood samples were taken.

Implications of the Findings

  • The reference intervals found in this study were comparable to those found in warm-blooded breeds of horses, suggesting similarities across different horse types.
  • These values were also found to be influenced by the horses’ living conditions.
  • The location-specific reference intervals identified in this study could potentially assist veterinarians in livery yards in making better decisions for their patients.

Cite This Article

APA
Buendia A, Teng KT, Camino E, Dominguez L, Cruz-Lopez F. (2021). Influence of multiple factors on hematologic reference intervals in horses residing in livery yards in Spain. Vet Clin Pathol, 50(2), 273-277. https://doi.org/10.1111/vcp.12965

Publication

Veterinary clinical pathology
ISSN: 1939-165X
NlmUniqueID: 9880575
Country: United States
Language: English
Volume: 50
Issue: 2
Pages: 273-277

Researcher Affiliations

Buendia, Aranzazu
  • VISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
Teng, Kendy Tzu-Yun
  • VISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
Camino, Eliazar
  • VISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
  • Animal Health Department, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.
Dominguez, Lucas
  • VISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.
  • Animal Health Department, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.
Cruz-Lopez, Fatima
  • VISAVET Health Surveillance Centre, Universidad Complutense, Madrid, Spain.

MeSH Terms

  • Animals
  • Blood Cell Count / veterinary
  • Erythrocyte Count / veterinary
  • Hematocrit / veterinary
  • Horses / physiology
  • Reference Values
  • Spain

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Citations

This article has been cited 5 times.
  1. Silva G, Queiroga FL, Cruz Z, Maia A, Silvestre-Ferreira AC. Coagulation Profile of the Healthy Miranda's Donkey. Animals (Basel) 2024 Jul 10;14(14).
    doi: 10.3390/ani14142031pubmed: 39061493google scholar: lookup
  2. Teng KT, Brodbelt DC, Church DB, O'Neill DG. Life tables of annual life expectancy and risk factors for mortality in cats in the UK. J Feline Med Surg 2024 May;26(5):1098612X241234556.
    doi: 10.1177/1098612X241234556pubmed: 38714312google scholar: lookup
  3. Oddsdóttir C, Jónsdóttir HK, Sturludóttir E, Vilanova XM. The Effect of Repeated Blood Harvesting from Pregnant Mares on Haematological Variables. Animals (Basel) 2024 Feb 28;14(5).
    doi: 10.3390/ani14050745pubmed: 38473131google scholar: lookup
  4. Oddsdóttir C, Jónsdóttir HK, Sturludóttir E. Haematological reference intervals for pregnant Icelandic mares on pasture. Acta Vet Scand 2023 Dec 15;65(1):57.
    doi: 10.1186/s13028-023-00721-xpubmed: 38102616google scholar: lookup
  5. Yan TY, Teng KT. Trends in Animal Shelter Management, Adoption, and Animal Death in Taiwan from 2012 to 2020. Animals (Basel) 2023 Apr 24;13(9).
    doi: 10.3390/ani13091451pubmed: 37174488google scholar: lookup
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