Interleukin 5-dependent inflammatory eosinophil subtype involved in allergic insect bite hypersensitivity of horses.
Abstract: No abstract available
Publication Date: 2023-08-22 PubMed ID: 37605865DOI: 10.1111/all.15859Google Scholar: Lookup
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- Journal Article
Cite This Article
APA
Pantelyushin S, Rhiner T, Jebbawi F, Sella F, Waldern N, Lam J, Chemnitzer A, Fricker A, Schoster A, Birkmann K, Widmer D, Canonica F, Fettelschoss-Gabriel A.
(2023).
Interleukin 5-dependent inflammatory eosinophil subtype involved in allergic insect bite hypersensitivity of horses.
Allergy.
https://doi.org/10.1111/all.15859 Publication
Researcher Affiliations
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
- Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
- Department of Dermatology, University Hospital Zurich, Schlieren, Switzerland.
- Faculty of Medicine, University of Zurich, Zurich, Switzerland.
- Evax AG, Guntershausen, Switzerland.
Grant Funding
- Evax AG
- 40B2-0_194689 / Swiss Bridge Foundation (SNF BRIDGE)
References
This article includes 6 references
- Fettelschoss-Gabriel A, Birkmann K, Pantelyushin S, Kundig TM. Molecular mechanisms and treatment modalities in equine Culicoides hypersensitivity. Vet J 2021;276:105741.
- Rothenberg ME, Hogan SP. The eosinophil. Annu Rev Immunol 2006;24:147-174.
- Fettelschoss-Gabriel A, Fettelschoss V, Olomski F. Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses. Allergy 2019;74(3):572-582.
- Mesnil C, Raulier S, Paulissen G. Lung-resident eosinophils represent a distinct regulatory eosinophil subset. J Clin Invest 2016;126(9):3279-3295.
- Van Hulst G, Batugedara HM, Jorssen J, Louis R, Bureau F, Desmet CJ. Eosinophil diversity in asthma. Biochem Pharmacol 2020;179:113963.
- Blanchard C, Rothenberg ME. Biology of the eosinophil. Adv Immunol 2009;101:81-121.
Citations
This article has been cited 5 times.- Jebbawi F, Olomski F, Inversini V, Keller G, Rhiner T, Waldern N, Lam J, Pantelyushin S, Canonica F, Birkmann K, Johansen P, Kündig TM, Fettelschoss-Gabriel A. Anti-IL-5 Vaccination Dampens Allergen-Specific IgE Levels and Modulates IL-4 and IL-5 Th2 Cytokines in Skin Allergy of Mice and Horses. Allergy 2025 Dec;80(12):3377-3390.
- Sanchez Santos A, Socorro Avila I, Galvan Fernandez H, Cazorla Rivero S, Lemes Castellano A, Cabrera Lopez C. Eosinophils: old cells, new directions. Front Med (Lausanne) 2024;11:1470381.
- Schwarz E, Jebbawi F, Keller G, Rhiner T, Fricker A, Waldern N, Canonica F, Schoster A, Fettelschoss-Gabriel A. Phenotypic Shift of an Inflammatory Eosinophil Subset into a Steady-State Resident Phenotype after 2 Years of Vaccination against IL-5 in Equine Insect Bite Hypersensitivity. Vet Sci 2024 Oct 5;11(10).
- Jebbawi F, Chemnitzer A, Dietrich M, Pantelyushin S, Lam J, Rhiner T, Keller G, Waldern N, Canonica F, Fettelschoss-Gabriel A. Cytokines and chemokines skin gene expression in correlation with immune cells in blood and severity in equine insect bite hypersensitivity. Front Immunol 2024;15:1414891.
- Gmel AI, Mikko S, Ricard A, Velie BD, Gerber V, Hamilton NA, Neuditschko M. Using high-density SNP data to unravel the origin of the Franches-Montagnes horse breed. Genet Sel Evol 2024 Jul 10;56(1):53.
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