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Theriogenology2018; 125; 210-215; doi: 10.1016/j.theriogenology.2018.11.004

Introduction of a new fetal examination protocol for on-field and clinical equine practice.

Abstract: Prepartum fetal surveillance techniques have been widely used in both human and veterinary obstetrics, although these tests differ in their sensitivity for the assessment of fetal well-being. In equine reproduction, the 'gold standard' examination technique is the equine biophysical profile (EBP) described by Virginia Reef in 1995. Although this fetal assessment has many benefits, its accuracy, sensitivity and specificity have not been evaluated so far. In this study, 129 late-term pregnant mares were scanned twice in their last month of gestation using two different protocols (the EBP and a new, rapid examination protocol, REP) in order to determine the accuracy of these tests. The REP included the determination of fetal heart rate, fetal aortic diameter and the combined thickness of the uteroplacental unit. Twenty-seven fetuses proved to be compromised and 102 mares had healthy asymptomatic foals. Statistical analyses showed slight differences in test sensitivity (81.48% and 85.19%), specificity (83.3% and 87.25%) and accuracy (82.95% and 86.82%) for EBP and REP, respectively. Furthermore, a statistically significant interchangeability could be demonstrated between the two methods. It is concluded that, depending on the prevalence of the disease (here: compromised state), both methods are useful for the diagnosis of fetal abnormalities and make it possible to provide satisfactory care for broodmares and their fetuses.
Publication Date: 2018-11-13 PubMed ID: 30469011DOI: 10.1016/j.theriogenology.2018.11.004Google Scholar: Lookup
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  • Journal Article

Summary

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This research invesigated two ultrasound-based techniques for assessing the health of unborn foals. The researchers found both the established Equine Biophysical Profile (EBP) and their newly developed Rapid Examination Protocol (REP) to have comparable accuracy, and both could effectively identify abnormalities in foals before birth.

Background

  • The authors of the paper underline that prepartum surveillance is very important in both human and veterinary obstetrics to ensure the well-being of the fetus. In equine obstetrics, the current ‘gold standard’ is the equine biophysical profile (EBP), a test developed by Virginia Reef in 1995.
  • Despite its widespread use, the EBP’s accuracy, sensitivity, and specificity hadn’t yet been thoroughly evaluated.

Methods

  • The researchers studied 129 late-term pregnant mares, scanning each twice in the last month of their pregnancies. They used both the established EBP and a newly-developed test, the Rapid Examination Protocol (REP). The study design aimed to compare the accuracy of the two tests.
  • The REP is a quicker process than the EBP and involves evaluating the fetal heart rate, fetal aortic diameter, and the combined thickness of the uteroplacental unit.

Results

  • The two methods uncovered that 27 foals were compromised and 102 mares were carrying healthy, asymptomatic foals.
  • Statistical analysis revealed that the sensitivity, specificity, and accuracy of the EBP and the REP were quite close. EBP’s scores were 81.48%, 83.3%, and 82.95% respectively, while REP’s were slightly higher at 85.19%, 87.25%, and 86.82%.
  • In addition, the researchers found statistically significant interchangeability between the EBP and the REP, suggesting either could be employed without significant loss of accuracy.

Conclusions

  • The authors concluded that based on the prevalence of the disease or compromising conditions in the equine population studied, both the EBP and the REP are effective and reliable methods to diagnose fetal abnormalities in horses. Using either would help to ensure quality care for pregnant mares and their unborn foals.

Cite This Article

APA
Vincze B, Baska F, Papp M, Szenci O. (2018). Introduction of a new fetal examination protocol for on-field and clinical equine practice. Theriogenology, 125, 210-215. https://doi.org/10.1016/j.theriogenology.2018.11.004

Publication

ISSN: 1879-3231
NlmUniqueID: 0421510
Country: United States
Language: English
Volume: 125
Pages: 210-215
PII: S0093-691X(18)31076-8

Researcher Affiliations

Vincze, Boglárka
  • MTA-SZIE Large Animal Clinical Research Group, H-2225, Üllő, Hungary; Department of Animal Breeding, Nutrition and Laboratory Animal Science, University of Veterinary Medicine, H-1078, Budapest, Hungary. Electronic address: Vincze.Boglarka@univet.hu.
Baska, Ferenc
  • Department of Exotic Animal and Wildlife Medicine, University of Veterinary Medicine, H-1078, Budapest, Hungary.
Papp, Márton
  • Centre for Bioinformatics, University of Veterinary Medicine, Budapest, Hungary.
Szenci, Ottó
  • MTA-SZIE Large Animal Clinical Research Group, H-2225, Üllő, Hungary.

MeSH Terms

  • Animals
  • Female
  • Fetal Development
  • Fetal Monitoring
  • Fetus / physiology
  • Horses / physiology
  • Pregnancy
  • Pregnancy, Animal
  • Ultrasonography, Prenatal / veterinary

Citations

This article has been cited 3 times.
  1. Bevevino KE, Cohen ND, Gordon SG, Navas de Solis C. Feasibility of a point-of-care ultrasound protocol for cardiorespiratory evaluation of horses in different clinical settings. J Vet Intern Med 2023 May-Jun;37(3):1223-1232.
    doi: 10.1111/jvim.16674pubmed: 36975771google scholar: lookup
  2. Gao Y, Hannan MA, Murata K, Rajabi-Toustani R, Nambo Y. Ultrasonographic examination of equine fetal growth parameters throughout gestation in pony for Equine-Assisted Therapy. J Vet Med Sci 2022 Jan 7;84(1):74-81.
    doi: 10.1292/jvms.21-0301pubmed: 34819425google scholar: lookup
  3. Cruz-Aleixo AS, Lima MCF, Albuquerque ALH, Teixeira RT, Paula RA, Grandi MC, Ferreira DOL, Tsunemi MH, Chiacchio SB, Lourenço MLG. Echocardiographic evaluation in Dorper ovine fetuses: Applications and limitations. Vet Med Sci 2021 Mar;7(2):417-423.
    doi: 10.1002/vms3.384pubmed: 33118701google scholar: lookup