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Isolation of Arcanobacterium hippocoleae from a case of placentitis and stillbirth in a mare.

Abstract: Based on the scarcity of reports in veterinary medicine literature, it appears that Arcanobacterium spp. are rarely isolated from horses. Recently, a single isolate from vaginal discharge in a mare was characterized as a new species, Arcanobacterium hippocoleae. The present report describes a case of necrosuppurative placentitis and stillbirth in an American Quarterhorse mare. Numerous colonies of irregular, Gram-positive, rod-shaped bacteria were observed by histological examination within fibrin lattice associated with placental lesions. Arcanobacterium hippocoleae was isolated in large numbers from the placenta, lung, and stomach contents. To the authors' knowledge, this is the first report of placentitis associated with Arcanobacterium spp. in a horse and the third reported isolation of A. hippocoleae from a horse.
Publication Date: 2008-09-09 PubMed ID: 18776114DOI: 10.1177/104063870802000532Google Scholar: Lookup
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Summary

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The researchers identified and analyzed a rare infection in a horse caused by the bacterium Arcanobacterium hippocoleae, which led to inflammation of the placenta and stillbirth.

About the Research

  • This study delves into an uncommonly reported case of a horse being infected with the Arcanobacterium spp bacteria, specifically the Arcanobacterium hippocoleae species.
  • Research of this nature is critical but scarcely found in veterinary medicine, making this case of immense importance to the broader veterinary community.

Case Description

  • An American Quarterhorse mare endured necrosuppurative placentitis, a severe infection-related inflammation of the placenta, and eventually stillbirth.
  • Histological examination showed numerous colonies of irregular, Gram-positive, rod-shaped bacteria within the fibrin lattice linked to placental lesions.
  • The bacterium Arcanobacterium hippocoleae was identified in large numbers from the placenta, lung, and stomach.

Significance of Findings

  • This case represents the first report of placentitis associated with Arcanobacterium spp. in a horse, adding a significant finding to the existing knowledge about the implications of bacterial infections in horses.
  • It’s also the third reported isolation of A. hippocoleae originating from a horse, showcasing the rarity of this bacterial infection.
  • The findings could pave the way for more comprehensive studies on the pathogenesis of these infectious agents in horses, leading to improved diagnostics and therapeutic interventions in veterinary practice.

Cite This Article

APA
Bemis DA, Bryant MJ, Kania SA, Newman SJ. (2008). Isolation of Arcanobacterium hippocoleae from a case of placentitis and stillbirth in a mare. J Vet Diagn Invest, 20(5), 688-691. https://doi.org/10.1177/104063870802000532

Publication

ISSN: 1040-6387
NlmUniqueID: 9011490
Country: United States
Language: English
Volume: 20
Issue: 5
Pages: 688-691

Researcher Affiliations

Bemis, David A
  • Department of Comparative Medicine, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37901-1071, USA. bemis@utk.edu
Bryant, Mary Jean
    Kania, Stephen A
      Newman, Shelley J

        MeSH Terms

        • Actinomycetales / genetics
        • Actinomycetales / isolation & purification
        • Actinomycetales Infections / pathology
        • Actinomycetales Infections / veterinary
        • Animals
        • DNA Primers
        • Female
        • Horses
        • Placenta / microbiology
        • Placenta / pathology
        • Polymerase Chain Reaction
        • Pregnancy
        • RNA, Bacterial / genetics
        • RNA, Ribosomal, 16S / genetics
        • Stillbirth / veterinary

        Citations

        This article has been cited 1 times.
        1. Ayalew LE, Mekuria ZH, Despres B, Saab ME, Ojha S. Genome Sequence Comparisons between Small and Large Colony Phenotypes of Equine Clinical Isolates of Arcanobacterium hippocoleae. Animals (Basel) 2024 May 29;14(11).
          doi: 10.3390/ani14111609pubmed: 38891657google scholar: lookup