Analyze Diet
Equine veterinary journal2015; 48(4); 451-456; doi: 10.1111/evj.12456

Laser surgery as a treatment for histologically confirmed sarcoids in the horse.

Abstract: Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long-term follow-up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid. Objective: To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence. Methods: Retrospective time-to-event analysis. Methods: Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow-up information was obtained by telephone questionnaire. Results: Ninety-nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02-2.56 and 1.11-14.7, respectively). Conclusions: Laser resection of sarcoids in the horse has a positive post operative prognosis. Further work is required to fully evaluate risk factors for recurrence fully.
Publication Date: 2015-07-31 PubMed ID: 25959259DOI: 10.1111/evj.12456Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study examines laser surgery’s effectiveness to treat histologically validated sarcoid in horses. It seeks to establish the success rate following this procedure as the sole treatment and evaluates risk factors for recurrence.

Objective and Methods

  • The main objective of the study was to establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids in horses. The study also sought to evaluate the risk factors for the recurrence of the condition.
  • All the horses included in the research had had laser surgery to remove at least one sarcoid. The treatment was performed between 1 July 2005 and 1 September 2012. Crucially, no previous known or concurrent veterinary treatment was administered to these horses.
  • To ensure legitimacy, each case’s diagnosis was confirmed through histology. All the clinical data were retrieved from the hospital database and follow-up information was collected through phone questionnaires.

Results of the Study

  • The analysis included 99 horses with a total of 235 sarcoids. A substantial 82 out of the total (or 83%) displayed no recurrence of the removed sarcoids.
  • Furthermore, 71 horses (approximately 72%) exhibited no occurrence of any sarcoids following the surgical procedure.
  • An interesting finding emerged in the case of horses with sarcoids on their head and neck and those with verrucose or wart-like growths. These cases demonstrated an increased risk of recurrence, with hazard ratios of 1.61 and 4.03 respectively and 95% confidence intervals of 1.02-2.56 and 1.11-14.7. This essentially means that the risks of sarcoid recurrence in horses were higher when the growths were present on the horse’s neck and head or when the sarcoids were verrucose in nature.

Conclusions

  • The research concludes that laser resection of sarcoids in the horse has a generally positive postoperative prognosis based on the relatively high percentage of cases with no recurrence of the condition.
  • However, the study points out that further work needs to be done to thoroughly evaluate the risk factors for recurrence. This could involve studying larger samples or implementing different research methodologies to gain a more nuanced understanding of the complexities associated with the recurrence of the condition following surgery.

Cite This Article

APA
Compston PC, Turner T, Wylie CE, Payne RJ. (2015). Laser surgery as a treatment for histologically confirmed sarcoids in the horse. Equine Vet J, 48(4), 451-456. https://doi.org/10.1111/evj.12456

Publication

ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 48
Issue: 4
Pages: 451-456

Researcher Affiliations

Compston, P C
  • Rossdales Equine Hospital, Newmarket, Suffolk, UK.
Turner, T
  • Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Edinburgh, UK.
Wylie, C E
  • Rossdales Equine Hospital, Newmarket, Suffolk, UK.
Payne, R J
  • Rossdales Equine Hospital, Newmarket, Suffolk, UK.

MeSH Terms

  • Animals
  • Female
  • Horse Diseases / surgery
  • Horses
  • Laser Therapy / veterinary
  • Male
  • Proportional Hazards Models
  • Retrospective Studies
  • Skin Neoplasms / surgery
  • Skin Neoplasms / veterinary

Citations

This article has been cited 5 times.
  1. Saba C, Eggleston R, Parks A, Peroni J, Sjoberg E, Rice S, Tyma J, Williams J, Grosenbaugh D, Leard AT. ALVAC-fIL2, a feline interleukin-2 immunomodulator, as a treatment for sarcoids in horses: A pilot study. J Vet Intern Med 2022 May;36(3):1179-1184.
    doi: 10.1111/jvim.16425pubmed: 35416353google scholar: lookup
  2. Giraldo A, Pinard CL, Plattner BL, Dubois MS. Periocular sarcoid with bone invasion in a Thoroughbred mare. Can Vet J 2020 Apr;61(4):415-419.
    pubmed: 32255829
  3. Monteiro MM, de Castro ELA, Pereira AJM, Thiesen R, Thiesen RMC, Salvarani FM. BCG Immunotherapy in Equine Sarcoid Treatment: Mechanisms, Clinical Efficacy, and Challenges in Veterinary Oncology. Viruses 2025 Sep 29;17(10).
    doi: 10.3390/v17101322pubmed: 41157593google scholar: lookup
  4. Smith CH, Stewart HL, Stefanovski D, Levine DG. Outcomes following autologous tumor tissue implantation with or without concurrent antineoplastic therapies in the treatment of sarcoids in 50 equids. Front Vet Sci 2025;12:1559519.
    doi: 10.3389/fvets.2025.1559519pubmed: 40417356google scholar: lookup
  5. Karalus W, Subharat S, Orbell G, Vaatstra B, Munday JS. Equine sarcoids: A clinicopathologic study of 49 cases, with mitotic count and clinical type predictive of recurrence. Vet Pathol 2024 May;61(3):357-365.
    doi: 10.1177/03009858231209408pubmed: 37937724google scholar: lookup