Leptospiral infection in aborted equine foetuses.
Abstract: During an investigation of equine abortion, leptospiral infection was demonstrated in nine out of 22 foetuses examined by immunofluorescence and culture. Strains belonging to four serogroups (Australis, Pomona, Hebdomadis and Icterohaemorrhagiae) were isolated. The age of leptospira infected foetuses ranged from six months to term.
Publication Date: 1983-10-01 PubMed ID: 6357776DOI: 10.1111/j.2042-3306.1983.tb01811.xGoogle Scholar: Lookup
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- Journal Article
Summary
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This study investigated aborting horses, where it was detected that nine out of 22 foetuses had leptospiral infection. Various strains of this bacteria were identified within four serogroups, and the ages of the infected foetuses ranged from six months to full term.
About the Research
- This research aimed to explore the possible cause of abortions in horses, focusing on a specific bacterial infection – Leptospira.
- The study involved examining 22 aborted horse foetuses for signs of a leptospiral infection.
Methodology
- To determine whether Leptospira bacteria were present in the foetuses, the investigators used two laboratory techniques: immunofluorescence and culture.
- Immunofluorescence is a method that uses fluorescent dye to visualize proteins or other substances in cells and tissues, thus helping to detect the presence of bacteria.
- Culture is a technique used to grow and isolate microorganisms, including bacteria, allowing researchers to identify the specific type(s) of bacteria present.
Findings
- Leptospiral infection was identified in nine out of the 22 foetuses, making it a possible contributor to the abortions experienced by the horses.
- After culturing the bacteria, the researchers found strains from four different serogroups: Australis, Pomona, Hebdomadis, and Icterohaemorrhagiae. A serogroup is a division within a species of bacteria or viruses, classified together based on shared antigenic characteristics.
Additional Observations
- It was noted that the ages of the foetuses infected with the bacteria ranged from six months to full term. This observation could hold key information for understanding at which stages horses are susceptible to leptospiral infection and when monitoring or treatments might be most effectively implemented.
Cite This Article
APA
Ellis WA, Bryson DG, O'Brien JJ, Neill SD.
(1983).
Leptospiral infection in aborted equine foetuses.
Equine Vet J, 15(4), 321-324.
https://doi.org/10.1111/j.2042-3306.1983.tb01811.x Publication
Researcher Affiliations
MeSH Terms
- Abortion, Veterinary
- Animals
- Antibodies, Bacterial / analysis
- Female
- Fetal Diseases / diagnosis
- Fetal Diseases / veterinary
- Fluorescent Antibody Technique
- Horse Diseases / diagnosis
- Horses
- Leptospira / immunology
- Leptospira / isolation & purification
- Leptospirosis / diagnosis
- Leptospirosis / veterinary
- Pregnancy
Citations
This article has been cited 10 times.- Bonhomme D, Werts C. Host and Species-Specificities of Pattern Recognition Receptors Upon Infection With Leptospira interrogans. Front Cell Infect Microbiol 2022;12:932137.
- Båverud V, Gunnarsson A, Engvall EO, Franzén P, Egenvall A. Leptospira seroprevalence and associations between seropositivity, clinical disease and host factors in horses. Acta Vet Scand 2009 Mar 30;51(1):15.
- Wilkie IW, Prescott JF, Hazlett MJ, Maxie MG, van Dreumel AA. Giant cell hepatitis in four aborted foals: A possible leptospiral infection. Can Vet J 1988 Dec;29(12):1003-4.
- Kingscote B. Leptospiral antibodies in cattle in alberta and evidence of an emerging serovar. Can Vet J 1988 Aug;29(8):647-53.
- Szeredi L, Haake DA. Immunohistochemical identification and pathologic findings in natural cases of equine abortion caused by leptospiral infection. Vet Pathol 2006 Sep;43(5):755-61.
- Lees VW, Gale SP. Titers to Leptospira species in horses in Alberta. Can Vet J 1994 Oct;35(10):636-40.
- Kitson-Piggot AW, Prescott JF. Leptospirosis in horses in Ontario. Can J Vet Res 1987 Oct;51(4):448-51.
- Żmudzki J, Ostrowska M, Arent Z, Frant M, Kochanowski M, Nowak A, Zębek S, Kalinowski D, Podgórska K. Seroprevalence of equine leptospirosis in Poland (2019-2023). Equine Vet J 2026 Mar;58(2):523-532.
- Zečević I, Picardeau M, Vince S, Hađina S, Perharić M, Štritof Z, Stevanović V, Benvin I, Turk N, Lohman Janković I, Habuš J. Association between Exposure to Leptospira spp. and Abortion in Mares in Croatia. Microorganisms 2024 May 21;12(6).
- Hamond C, Adam EN, Stone NE, LeCount K, Anderson T, Putz EJ, Camp P, Hicks J, Stuber T, van der Linden H, Bayles DO, Sahl JW, Schlater LK, Wagner DM, Nally JE. Identification of equine mares as reservoir hosts for pathogenic species of Leptospira. Front Vet Sci 2024;11:1346713.
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