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Veterinary journal (London, England : 1997)2022; 291; 105926; doi: 10.1016/j.tvjl.2022.105926

Management of equine sarcoids.

Abstract: Sarcoids are the most common cutaneous neoplasm of the horse, arising as a result of a neoplastic proliferation of fibroblasts associated with infection with bovine papillomavirus, most notably types 1 and 2. Although they do not metastasise, they are locally invasive and aggressive, and can lead to important welfare concerns, interfere with tack and therefore impede athleticism, and undoubtedly lead to a reduction in the value of affected horses. This review discusses the evidence behind the most commonly used treatments for equine sarcoids. The most commonly used treatments are discussed. No one treatment is universally successful, and there are many treatments with varying level of scientific evaluation and reported success rates.
Publication Date: 2022-11-02 PubMed ID: 36334801DOI: 10.1016/j.tvjl.2022.105926Google Scholar: Lookup
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  • Journal Article
  • Review

Summary

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This research article reviews different treatments for equine sarcoids, a common skin tumor in horses caused by bovine papillomavirus infection, evaluating their success rates and the level of scientific evidence supporting their use.

Understanding Equine Sarcoids

  • Equine sarcoids are a common skin tumor found in horses. These tumors don’t spread to other parts of the body, but they are invasive and can aggressively proliferate at the site of infection.
  • Sarcoids arise due to an infection with the bovine papillomavirus, especially types 1 and 2, which leads to abnormal growth of fibroblasts, the cells that produce collagen and other fibers.
  • These sarcoids are a serious welfare concern because they can disrupt the horse’s performance, interfere with the fit of its equipment, and ultimately reduce the animal’s value.

Treatment Options for Equine Sarcoids

  • The main focus of the research paper is to evaluate the popular treatments used to manage equine sarcoids. The authors discuss the efficacy of these treatments and assess the amount of scientific data supporting their use.
  • The article emphasizes that no one treatment is universally successful. That means different treatment methods may work differently depending on various factors like the horse’s health status, the location and size of the sarcoids, and the treatment’s side effects.
  • Despite the many treatments available, their success rates vary widely. The authors of this research paper stress the importance of evaluating the research supporting these treatments to ensure effectiveness and safety.

Significance of the Study

  • This research paper is valuable because it provides an overview of the various available treatments for equine sarcoids. This can help veterinarians choose the best treatment for their affected equine patients, considering different factors like the horse’s condition and the scientifically-backed efficacy of the treatments.
  • Also, by examining the scientific evidence behind these treatments, it can stimulate further research to build a stronger foundation for effective sarcoid management in horses.

Cite This Article

APA
Hollis AR. (2022). Management of equine sarcoids. Vet J, 291, 105926. https://doi.org/10.1016/j.tvjl.2022.105926

Publication

ISSN: 1532-2971
NlmUniqueID: 9706281
Country: England
Language: English
Volume: 291
Pages: 105926
PII: S1090-0233(22)00141-1

Researcher Affiliations

Hollis, Anna R
  • Cambridge Equine Hospital, Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK. Electronic address: arh207@cam.ac.uk.

MeSH Terms

  • Horses
  • Animals
  • Papillomavirus Infections / therapy
  • Papillomavirus Infections / veterinary
  • Horse Diseases / therapy
  • Bovine papillomavirus 1
  • Skin Neoplasms / therapy
  • Skin Neoplasms / veterinary
  • Sarcoidosis / veterinary

Citations

This article has been cited 4 times.
  1. Monteiro MM, de Castro ELA, Pereira AJM, Thiesen R, Thiesen RMC, Salvarani FM. BCG Immunotherapy in Equine Sarcoid Treatment: Mechanisms, Clinical Efficacy, and Challenges in Veterinary Oncology. Viruses 2025 Sep 29;17(10).
    doi: 10.3390/v17101322pubmed: 41157593google scholar: lookup
  2. Smith CH, Stewart HL, Stefanovski D, Levine DG. Outcomes following autologous tumor tissue implantation with or without concurrent antineoplastic therapies in the treatment of sarcoids in 50 equids. Front Vet Sci 2025;12:1559519.
    doi: 10.3389/fvets.2025.1559519pubmed: 40417356google scholar: lookup
  3. Sobhy NM, Refaai W, Kumar R, Bottros Youssef CR, Goyal SM. Molecular Characterization of Bovine Deltapapillomavirus in Equine Sarcoids in Egypt. Vet Med Int 2025;2025:9773642.
    doi: 10.1155/vmi/9773642pubmed: 39803352google scholar: lookup
  4. Karalus W, Subharat S, Orbell G, Vaatstra B, Munday JS. Equine sarcoids: A clinicopathologic study of 49 cases, with mitotic count and clinical type predictive of recurrence. Vet Pathol 2024 May;61(3):357-365.
    doi: 10.1177/03009858231209408pubmed: 37937724google scholar: lookup