Measurement of intraocular pressure in healthy anesthetized horses during hoisting.
Abstract: To measure intraocular pressure (IOP) in horses during hoisting after induction of anesthesia. Methods: Prospective nonrandomized clinical study. Methods: Eighteen healthy adult horses aged [mean±standard deviation (SD)] 10±4.2 years and weighing 491±110 kg anesthetized for elective procedures. Methods: IOP was measured in the superior eye of each horse based on planned recumbency after induction of anesthesia. Measurements were taken directly after premedication with xylazine or detomidine with butorphanol, after induction with diazepam-ketamine, after intubation, when suspended by the hoist and on the operating table. During hoisting, the head was supported and the eye-heart height was measured to account for variations in head positioning among patients. IOPs were compared across time points using repeated-measures analysis of variance. Regression was used to compare IOP outcome with potential cofactors. Results: Compared with measurements after premedication (17.5±2.5 mmHg) (mean±SD), hoisting significantly increased IOP (32.4±15.3 mmHg) (p<0.01). The highest recorded IOP in the hoist was 80.0 (range, 16.0-80.0) mmHg. The difference in IOP between premedication and hoisting was 15.0±16.2 (range, -1.0 to 68.0) mmHg. Body weight had a significant effect on absolute IOP and change in IOP in the hoist (p<0.01). Conclusions: Hoist IOP was significantly higher than post-premedication IOP with heavier horses having higher hoist IOPs and greater increases in IOP. The clinician should take this relationship into account when anesthetizing and hoisting larger horses where an increase in IOP could be detrimental.
Copyright © 2017 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.
Publication Date: 2017-01-11 PubMed ID: 28539183DOI: 10.1016/j.vaa.2016.10.001Google Scholar: Lookup
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- Clinical Study
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Summary
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The research examines the changes in intraocular pressure (IOP) in anesthetized horses during hoisting and finds that hoisting significantly increases IOP, with heavier horses experiencing higher pressures. This indicates a potential risk during anesthesia and hoisting procedures for large horses.
Overview of Research Methodology
- The study was a prospective nonrandomized clinical examination of 18 healthy adult horses aged approximately 10 years and weighing roughly 491 kg that were anesthetized for elective procedures.
- The researchers measured IOP in the horses’ eyes at different stages, including after premedication, induction, intubation, suspension by a hoist, and positioning on the operating table.
- During the hoisting phase, the horse’s head was supported and the distance from the eye to the heart was measured to control for differences in head position among the patients.
- The researchers then compared IOP measurements across the different time points using repeated-measures analysis of variance, and regression was used to assess the relationship between IOP and potential cofactors.
Study Results
- Findings revealed that hoisting caused a significant increase in IOP compared to measurements taken after premedication, with the highest recorded IOP reaching 80.0 mmHg during hoisting.
- There was a marked contrast in IOP before premedication and during hoisting, suggesting that the latter had a distinct impact on intraocular pressure.
- Importantly, the researchers found a significant correlation between a horse’s body weight and both the absolute IOP and the change in IOP during hoisting, indicating that heavier horses had higher IOPs and experienced a greater increase in IOP during hoisting.
Conclusions and Implications
- The increase in intraocular pressure during hoisting and its correlation with body weight highlights potential risks during anesthesia and hoisting procedures, particularly for larger horses.
- Clinicians need to account for these potential complications when planning and executing such procedures, as an increase in IOP could be detrimental to the horse’s health.
Cite This Article
APA
Monk CS, Brooks DE, Granone T, Garcia-Pereira FL, Melesko A, Plummer CE.
(2017).
Measurement of intraocular pressure in healthy anesthetized horses during hoisting.
Vet Anaesth Analg, 44(3), 502-508.
https://doi.org/10.1016/j.vaa.2016.10.001 Publication
Researcher Affiliations
- Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
- Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
- Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
- Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
- Federated Investors, New York, NY, USA.
- Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA. Electronic address: PlummerC@ufl.edu.
MeSH Terms
- Anesthesia / veterinary
- Animals
- Elective Surgical Procedures / veterinary
- Horses
- Intraocular Pressure / physiology
- Ketamine
- Moving and Lifting Patients / adverse effects
- Moving and Lifting Patients / veterinary
- Preanesthetic Medication
- Prospective Studies
- Tonometry, Ocular / veterinary
- Xylazine
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