Mixed infection of Leishmania (Leishmania) infantum and Leishmania (Viannia) braziliensis in a mare (Equus ferus caballus) from Minas Gerais State, Southeastern Brazil.
Abstract: Equine leishmaniasis is a widespread disease in Brazil, mainly caused by Leishmania (Viannia) braziliensis, with occasional cases involving Leishmania (Leishmania) infantum. This study reports a mixed infection in a 6-year-old mare from rural Itabirito, Minas Gerais, Brazil. The mare exhibited nodular cutaneous lesions on all limbs but had no other health issues. Skin and bone marrow samples were collected and analyzed using parasitological and molecular methods targeting the hsp70 gene and ITS1 region. Both L. (V.) braziliensis and L. (L.) infantum were identified, confirming a mixed infection. Notably, this is the first confirmed isolation of L. (V.) braziliensis from equine cutaneous lesions. These findings highlight the importance of recognizing equids as potential reservoirs in the transmission of leishmaniasis, which has implications for disease control and epidemiological surveillance.
Copyright © 2025. Published by Elsevier Inc.
Publication Date: 2025-07-09 PubMed ID: 40645304DOI: 10.1016/j.jevs.2025.105649Google Scholar: Lookup
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APA
Martins ALM, Estevam LGTM, Freire MA, Lima ACVMDR, de Oliveira FCB, Dutra-Rêgo F, Carvalho GML, Ribeiro VM, Paz GF.
(2025).
Mixed infection of Leishmania (Leishmania) infantum and Leishmania (Viannia) braziliensis in a mare (Equus ferus caballus) from Minas Gerais State, Southeastern Brazil.
J Equine Vet Sci, 152, 105649.
https://doi.org/10.1016/j.jevs.2025.105649 Publication
Researcher Affiliations
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil. Electronic address: gumayr@yahoo.com.br.
- Santo Agostinho Veterinary Hospital, Avenida Amazonas, 2218 - Santo Agostinho, Belo Horizonte - MG, 30180-003, Brazil.
- René Rachou Institute, Fiocruz Minas, Avenida Augusto de Lima, 1715 - Centro, Belo Horizonte, Minas Gerais, 30190-009, Brazil.
MeSH Terms
- Animals
- Horses
- Brazil / epidemiology
- Leishmania braziliensis / isolation & purification
- Leishmania infantum / isolation & purification
- Horse Diseases / parasitology
- Horse Diseases / epidemiology
- Female
- Leishmaniasis, Visceral / veterinary
- Leishmaniasis, Visceral / epidemiology
- Leishmaniasis, Visceral / parasitology
- Coinfection / veterinary
- Coinfection / parasitology
- Coinfection / epidemiology
Conflict of Interest Statement
Declaration of competing interest The authors declare no conflict of interest related to this manuscript. The research was conducted independently, and the authors have no financial, personal, or professional relationships that could influence the content or outcomes of the study.
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