Modeling climate change effects on some biochemical parameters in horse.

The research study examines the impact of climate change on several biochemical parameters in horses, with the study findings demonstrating that shifts in ambient temperature, relative humidity, and thermal-hygrometric conditions significantly influence these physiological markers.

Study Setup

• The study was performed over a three-year period (2021-23) and involved testing 16 Thoroughbred retired mares from a breeding farm in Kastamonu, Turkey.
• Various environmental parameters were monitored, including ambient temperature (AT), relative humidity (RH), ventilation (VT), and the Temperature-Humidity Index (THI) was calculated.
• Blood samples were collected monthly, and the serum was used to measure biochemical parameters, including total proteins, globulins, albumins, alkaline phosphatase, creatine kinase, lactate dehydrogenase, aspartate aminotransferase, blood urea nitrogen, γ-glutamyl transferase, and creatinine.

Statistical Analysis and Findings

• Using two-way repeated measure ANOVA, the researchers established that monthly variations significantly influenced AT, RH, and THI as well as all of the biochemical parameters noted earlier.
• Values for alkaline phosphatase, creatine kinase, lactate dehydrogenase, aspartate aminotransferase, and blood urea nitrogen increased during the warmer months. However, γ-glutamyl transferase levels decreased in the summer.
• The study results revealed a positive correlation between creatinine and ambient temperature, while lactate dehydrogenase and creatinine levels showed a negative correlation with relative humidity.

Study Implications

• The research outcome will be useful for monitoring the physiological state of horses subjected to climate change.
• Understanding this interaction between biochemical parameters and changing climate conditions will allow for better health management strategies for horses in regions experiencing significant climate variations.