[New drugs for horses and food-producing animals in 2022].

The research article discusses the new pharmaceutical drugs introduced in the German market for horses and food-producing animals in 2022, including a novel stem cell injection for horses, broadened use of cloprostenol (a synthetic prostaglandin analog) in goats, and drugs with higher active ingredient concentrations.

Introduction of RenuTend

• A novel stem cell injection suspension, RenuTend, has been presented in the German market in 2022. This drug is particularly meant for horses and stands as the inaugural solution in this discipline.
• The active ingredient in RenuTend is tenogenic primed equine allogeneic peripheral blood-derived mesenchymal stem cells. These are a type of regenerative medicine that originates from the peripheral blood of horses. Mesenchymal stem cells have been found to have therapeutic potential in many animal and human diseases, thanks to their immunomodulatory properties and capacity to differentiate into multiple cell types.
• The application of stem cell therapy in horses may help in the treatment of a variety of conditions, potentially including injuries to tendons, joints, and ligaments.

Extension of Cloprostenol Use

• The research highlights the extended approval of the synthetic prostaglandin F-analogue cloprostenol, under the brand name Syncroprost, now for use in goats.
• Prior to this, cloprostenol was likely utilized in other animal species given its known effect in reproductive management. It’s commonly used to control the estrus cycle, induce abortion, or treat reproductive disorders.
• The extension to goats can have significant implications in managing reproductive health for this particular food-producing animal group, improving efficiency in livestock industry.

Increased Active Ingredient Concentration

• For paracetamol and suxibuzone, two common drugs in veterinary medicine, versions with higher active ingredient content have been introduced in the market for horses and food-producing animals.
• Paracetamol is a well-known analgesic and antipyretic, often used for relief of pain and fever. Its increased dosage indicates a step towards more potent pain management strategies in animal care.
• Suxibuzone, similar to paracetamol, provides anti-inflammatory, analgesic, and antipyretic actions and is primarily used for the treatment of musculoskeletal disorders in horses.
• Higher active ingredient dosages can suggest a need for more potent treatment options, potentially due to an increase in the severity or prevalence of certain conditions, or possibly a reflection of improved understanding of the safe dosage ranges for these medications.