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The Journal of urology1986; 136(6); 1314-1315; doi: 10.1016/s0022-5347(17)45327-4

Nocardia epididymo-orchitis in an immunosuppressed patient.

Abstract: The immunocompromised patient after organ transplantation is susceptible to unusual and life-threatening infections. We report a case of epididymitis that evolved into testicular nocardiosis after cardiac transplantation. An awareness of the potential for these infections and early diagnosis may prevent extensive morbidity in the post-transplantation patient.
Publication Date: 1986-12-01 PubMed ID: 3773115DOI: 10.1016/s0022-5347(17)45327-4Google Scholar: Lookup
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Summary

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The research article discusses a rare case of epididymitis evolving into testicular nocardiosis in a patient after a heart transplant. The study brings attention to threats of uncommon infections in organ recipients who are immunocompromised.

Objective of the Study

  • The main objective of the research is to highlight the susceptibility of post-transplant patients, who are immunocompromised, to rare and potentially dangerous infections. It presents a case study where a heart transplant patient developed testicular nocardiosis from initial epididymitis.

Case Presentation

  • The study presents a case of a patient who received a heart transplant, following which he developed epididymitis, an inflammation of the tube at the back of the testicle that stores and carries sperm.
  • This condition further evolved into testicular nocardiosis, a rare bacterial infection caused by Nocardia, typically affecting individuals with weakened immune systems.

Significance of the Study

  • The researchers stress the importance of being aware of the potential of such unusual infections in post-transplant patients. Recognizing these infections early allows for timely intervention and reduces the morbidity risks.
  • The study contributes to the broader understanding of post-transplant complications and the importance of early diagnosis and treatment of such rare infections in this at-risk population.

Implications and Recommendations

  • The findings underscore the need for healthcare providers to have a high index of suspicion for unusual infections in post-transplant and immunocompromised patients. It advocates for early disease detection followed by prompt treatment to prevent serious complications.
  • More extensive research is recommended to further explore such infections and find strategies to predict, prevent, and treat them comprehensively.

Cite This Article

APA
Wheeler JS, Culkin DJ, O'Connell J, Winters G. (1986). Nocardia epididymo-orchitis in an immunosuppressed patient. J Urol, 136(6), 1314-1315. https://doi.org/10.1016/s0022-5347(17)45327-4

Publication

ISSN: 0022-5347
NlmUniqueID: 0376374
Country: United States
Language: English
Volume: 136
Issue: 6
Pages: 1314-1315

Researcher Affiliations

Wheeler, J S
    Culkin, D J
      O'Connell, J
        Winters, G

          MeSH Terms

          • Adult
          • Epididymitis / etiology
          • Epididymitis / microbiology
          • Epididymitis / pathology
          • Humans
          • Immune Tolerance
          • Male
          • Nocardia Infections / microbiology
          • Nocardia Infections / pathology
          • Orchitis / etiology
          • Orchitis / microbiology
          • Orchitis / pathology

          Citations

          This article has been cited 7 times.
          1. Sakamaki I, Ueno A, Kawasuji H, Miyajima Y, Kawago K, Hishikawa Y, Ikehata Y, Fujiuchi Y, Kitamura H, Yamamoto Y. Prostate abscess caused by Nocardia farcina. IDCases 2019;18:e00640.
            doi: 10.1016/j.idcr.2019.e00640pubmed: 31692509google scholar: lookup
          2. Scorey H, Daniel S. Nocardia farcinica bacteraemia presenting as a prostate abscess. IDCases 2016;5:24-6.
            doi: 10.1016/j.idcr.2016.06.001pubmed: 27419070google scholar: lookup
          3. Pimentel M, Nicolle LE, Qureshi S. Candida albicans epididymo-orchitis and fungemia in a patient with chronic myelogenous leukemia. Can J Infect Dis 1996 Sep;7(5):332-4.
            doi: 10.1155/1996/237967pubmed: 22514460google scholar: lookup
          4. Patel R, Paya CV. Infections in solid-organ transplant recipients. Clin Microbiol Rev 1997 Jan;10(1):86-124.
            doi: 10.1128/CMR.10.1.86pubmed: 8993860google scholar: lookup
          5. López E, Ferrero M, Lumbreras C, Gimeno C, González-Pinto I, Palengue E. A case of testicular nocardiosis and literature review. Eur J Clin Microbiol Infect Dis 1994 Apr;13(4):310-3.
            doi: 10.1007/BF01974607pubmed: 8070436google scholar: lookup
          6. Beaman BL, Beaman L. Nocardia species: host-parasite relationships. Clin Microbiol Rev 1994 Apr;7(2):213-64.
            doi: 10.1128/CMR.7.2.213pubmed: 8055469google scholar: lookup
          7. Inthasot S, Leemans S, Hing M, Vanderhulst J. Fever of unknown origin revealing testicular nocardiosis: a case report and literature review. BMC Infect Dis 2024 Jun 21;24(1):614.
            doi: 10.1186/s12879-024-09521-8pubmed: 38907186google scholar: lookup