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Home / Equine Research Bank / R Soc Open Sci / Non-invasive stress evaluation in domestic horses (Equus cab...
Royal Society open science2020; 7(2); 191994; doi: 10.1098/rsos.191994

Non-invasive stress evaluation in domestic horses (Equus caballus): impact of housing conditions on sensory laterality and immunoglobulin A.

Abstract: The study aimed to evaluate sensory laterality and concentration of faecal immunoglobulin A (IgA) as non-invasive measures of stress in horses by comparing them with the already established measures of motor laterality and faecal glucocorticoid metabolites (FGMs). Eleven three-year-old horses were exposed to known stressful situations (change of housing, initial training) to assess the two new parameters. Sensory laterality initially shifted significantly to the left and faecal FGMs were significantly increased on the change from group to individual housing and remained high through initial training. Motor laterality shifted significantly to the left after one week of individual stabling. Faecal IgA remained unchanged throughout the experiment. We therefore suggest that sensory laterality may be helpful in assessing acute stress in horses, especially on an individual level, as it proved to be an objective behavioural parameter that is easy to observe. Comparably, motor laterality may be helpful in assessing long-lasting stress. The results indicate that stress changes sensory laterality in horses, but further research is needed on a larger sample to evaluate elevated chronic stress, as it was not clear whether the horses of the present study experienced compromised welfare, which it has been proposed may affect faecal IgA.
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Publication Date: 2020-02-19 PubMed ID: 32257351PubMed Central: PMC7062079DOI: 10.1098/rsos.191994Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research explores the use of sensory laterality and faecal immunoglobulin A as non-invasive stress indicators in horses, assessing these against established measures, and evaluating their correlation with changes in housing and training.

Objective of the research

  • This study aims to evaluate new, non-invasive methods for measuring stress in horses. The researchers explore sensory laterality, which refers to the preferential use of one sensory organ or system over another, and faecal immunoglobulin A (IgA), a type of antibody that plays a crucial role in the immune function of mucous membranes.

Methodology

  • The researchers studied eleven three-year-old horses, which were subjected to known stress-inducing scenarios like change of housing and initial training.
  • The aim was to assess the impact of these conditions on sensory laterality and faecal IgA levels, comparing these with established stress indicators like motor laterality (one-sided bias in physical movement) and faecal glucocorticoid metabolites (FGMs), biochemical signs of stress.

Key findings

  • Change from group to individual housing significantly shifted sensory laterality to the left and increased faecal FGMs. This high FGM level remained through the initial training phase.
  • Motor laterality also shifted significantly to the left after one week of individual stabling, suggesting it may be a useful measure for long-term stress.
  • There was no change in faecal IgA throughout the experiment, indicating that this measure may not be as sensitive or relevant in this context.

Implications of the research

  • The results suggest that sensory laterality can be a useful tool for assessing acute, individual-level stress in horses. It presents as an objective behavioural parameter that is simple to observe.
  • Further research is needed to evaluate these findings on a larger sample size, especially to explore the potential link between chronic elevated stress and faecal IgA, as it was unclear in this study whether the horses’ welfare change interfered with the faecal IgA.

Cite This Article

APA
Marr I, Preisler V, Farmer K, Stefanski V, Krueger K. (2020). Non-invasive stress evaluation in domestic horses (Equus caballus): impact of housing conditions on sensory laterality and immunoglobulin A. R Soc Open Sci, 7(2), 191994. https://doi.org/10.1098/rsos.191994

Publication

Royal Society open science
ISSN: 2054-5703
NlmUniqueID: 101647528
Country: England
Language: English
Volume: 7
Issue: 2
Pages: 191994
PII: 191994

Researcher Affiliations

Marr, I
  • Department Equine Economics, Faculty Agriculture, Economics and Management, Nuertingen-Geislingen University, Neckarsteige 6-10, Nuertingen 72622, Germany.
  • Behavioral Physiology of Livestock, University of Hohenheim, Garbenstr. 17, Stuttgart 70599, Germany.
Preisler, V
  • Behavioral Physiology of Livestock, University of Hohenheim, Garbenstr. 17, Stuttgart 70599, Germany.
Farmer, K
  • School of Psychology & Neuroscience, University of St Andrews, St Andrews, Scotland KY16 9AJ, UK.
Stefanski, V
  • Behavioral Physiology of Livestock, University of Hohenheim, Garbenstr. 17, Stuttgart 70599, Germany.
Krueger, K
  • Department Equine Economics, Faculty Agriculture, Economics and Management, Nuertingen-Geislingen University, Neckarsteige 6-10, Nuertingen 72622, Germany.
  • Zoology/Evolutionary Biology, University of Regensburg, Universitaetsstr. 31, Regensburg 93053, Germany.

Conflict of Interest Statement

The author and co-authors of this manuscript have no competing interest.

References

This article includes 77 references
  1. Yarnell K, Hall C, Royle C, Walker SL. Domesticated horses differ in their behavioural and physiological responses to isolated and group housing.. Physiol Behav 2015 May 1;143:51-7.
    doi: 10.1016/j.physbeh.2015.02.040pubmed: 25725117google scholar: lookup
  2. Erber R, Wulf M, Aurich J, Rose-Meierhöfer S, Hoffmann G, von Lewinski M, Möstl E, Aurich C. Stress response of three-year-old horse mares to changes in husbandry system during initial equestrian training. J. Equine Vet. Sci. 33, 1088–1094.
    doi: 10.1016/j.jevs.2013.04.008google scholar: lookup
  3. Dhabhar FS. Enhancing versus suppressive effects of stress on immune function: implications for immunoprotection and immunopathology.. Neuroimmunomodulation 2009;16(5):300-17.
    doi: 10.1159/000216188pmc: PMC2790771pubmed: 19571591google scholar: lookup
  4. Kupriyanov R. The eustress concept: problems and outlooks. World J. Med. Sci. 11, 179–185.
    doi: 10.5829/idosi.wjms.2014.11.2.8433google scholar: lookup
  5. Miller GE, Chen E, Zhou ES. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans.. Psychol Bull 2007 Jan;133(1):25-45.
    doi: 10.1037/0033-2909.133.1.25pubmed: 17201569google scholar: lookup
  6. Stefanski V, Engler H. Effects of acute and chronic social stress on blood cellular immunity in rats.. Physiol Behav 1998 Jul;64(5):733-41.
    doi: 10.1016/S0031-9384(98)00127-9pubmed: 9817588google scholar: lookup
  7. Reyna-Garfias H, Miliar A, Jarillo-Luna A, Rivera-Aguilar V, Pacheco-Yepez J, Baeza I, Campos-Rodríguez R. Repeated restraint stress increases IgA concentration in rat small intestine.. Brain Behav Immun 2010 Jan;24(1):110-8.
    doi: 10.1016/j.bbi.2009.09.005pubmed: 19748568google scholar: lookup
  8. Jarillo-Luna A, Rivera-Aguilar V, Garfias HR, Lara-Padilla E, Kormanovsky A, Campos-Rodríguez R. Effect of repeated restraint stress on the levels of intestinal IgA in mice.. Psychoneuroendocrinology 2007 Jul;32(6):681-92.
    doi: 10.1016/j.psyneuen.2007.04.009pubmed: 17590521google scholar: lookup
  9. Muneta Y, Yoshikawa T, Minagawa Y, Shibahara T, Maeda R, Omata Y. Salivary IgA as a useful non-invasive marker for restraint stress in pigs.. J Vet Med Sci 2010 Oct;72(10):1295-300.
    doi: 10.1292/jvms.10-0009pubmed: 20467204google scholar: lookup
  10. Svobodová I, Chaloupková H, Končel R, Bartoš L, Hradecká L, Jebavý L. Cortisol and secretory immunoglobulin A response to stress in German shepherd dogs.. PLoS One 2014;9(3):e90820.
    doi: 10.1371/journal.pone.0090820pmc: PMC3956493pubmed: 24637917google scholar: lookup
  11. Bolufer P, Gandia A, Rodriguez A, Antonio P. Salivary corticosteroids in the study of adrenal function.. Clin Chim Acta 1989 Aug 15;183(2):217-25.
    doi: 10.1016/0009-8981(89)90337-9pubmed: 2791306google scholar: lookup
  12. Palme R. Monitoring stress hormone metabolites as a useful, non-invasive tool for welfare assessment in farm animals. Anim. Welf. 21, 331–337.
    doi: 10.7120/09627286.21.3.331google scholar: lookup
  13. Sheriff MJ, Dantzer B, Delehanty B, Palme R, Boonstra R. Measuring stress in wildlife: techniques for quantifying glucocorticoids.. Oecologia 2011 Aug;166(4):869-87.
    doi: 10.1007/s00442-011-1943-ypubmed: 21344254google scholar: lookup
  14. Balcombe JP, Barnard ND, Sandusky C. Laboratory routines cause animal stress.. Contemp Top Lab Anim Sci 2004 Nov;43(6):42-51.
    pubmed: 15669134
  15. Morrow CJ, Kolver ES, Verkerk GA, Matthews LR. Fecal glucocorticoid metabolites as a measure of adrenal activity in dairy cattle.. Gen Comp Endocrinol 2002 Apr;126(2):229-41.
    doi: 10.1006/gcen.2002.7797pubmed: 12030779google scholar: lookup
  16. Säkkinen H, Tornbeg J, Goddard PJ, Eloranta E, Ropstad E, Saarela S. The effect of blood sampling method on indicators of physiological stress in reindeer (Rangifer tarandus tarandus).. Domest Anim Endocrinol 2004 Mar;26(2):87-98.
    doi: 10.1016/j.domaniend.2003.07.002pubmed: 14757182google scholar: lookup
  17. Palme R, Fischer P, Schildorfer H, Ismail MN. Excretion of infused 14C-steroid hormones via faeces and urine in domestic livestock. Anim. Reprod. Sci. 43, 43–63.
    doi: 10.1016/0378-4320(95)01458-6google scholar: lookup
  18. Pawluski J, Jego P, Henry S, Bruchet A, Palme R, Coste C, Hausberger M. Low plasma cortisol and fecal cortisol metabolite measures as indicators of compromised welfare in domestic horses (Equus caballus).. PLoS One 2017;12(9):e0182257.
    doi: 10.1371/journal.pone.0182257pmc: PMC5590897pubmed: 28886020google scholar: lookup
  19. Padgett DA, Glaser R. How stress influences the immune response.. Trends Immunol 2003 Aug;24(8):444-8.
    doi: 10.1016/S1471-4906(03)00173-Xpubmed: 12909458google scholar: lookup
  20. Tsujita S, Morimoto K. Secretory IgA in saliva can be a useful stress marker.. Environ Health Prev Med 1999 Apr;4(1):1-8.
    doi: 10.1007/BF02931243pmc: PMC2723416pubmed: 21432164google scholar: lookup
  21. Campos-Rodríguez R, Godínez-Victoria M, Abarca-Rojano E, Pacheco-Yépez J, Reyna-Garfias H, Barbosa-Cabrera RE, Drago-Serrano ME. Stress modulates intestinal secretory immunoglobulin A.. Front Integr Neurosci 2013 Dec 2;7:86.
    doi: 10.3389/fnint.2013.00086pmc: PMC3845795pubmed: 24348350google scholar: lookup
  22. Newby TJ, Stokes CR. The intestinal immune system and oral vaccination.. Vet Immunol Immunopathol 1984 May;6(1-2):67-105.
    doi: 10.1016/0165-2427(84)90049-7pubmed: 6204436google scholar: lookup
  23. Bosch JA, Ring C, de Geus EJ, Veerman EC, Amerongen AV. Stress and secretory immunity.. Int Rev Neurobiol 2002;52:213-53.
    doi: 10.1016/S0074-7742(02)52011-0pubmed: 12498106google scholar: lookup
  24. May A. Evaluierung von Stressparametern beim Pferd im Zusammenhang mit dem Klinikaufenthalt. .
  25. Rogers LJ. Relevance of brain and behavioural lateralization to animal welfare. Appl. Anim. Behav. Sci. 127, 1–11.
    doi: 10.1016/j.applanim.2010.06.008google scholar: lookup
  26. Schultheiss OC, Riebel K, Jones NM. Activity inhibition: a predictor of lateralized brain function during stress?. Neuropsychology 2009 May;23(3):392-404.
    doi: 10.1037/a0014591pubmed: 19413452google scholar: lookup
  27. Neveu PJ. Lateralization and stress responses in mice: interindividual differences in the association of brain, neuroendocrine, and immune responses.. Behav Genet 1996 Jul;26(4):373-7.
    doi: 10.1007/BF02359481pubmed: 8771897google scholar: lookup
  28. Neveu PJ. Cerebral lateralization and the immune system.. Int Rev Neurobiol 2002;52:303-23.
    doi: 10.1016/S0074-7742(02)52014-6pubmed: 12498109google scholar: lookup
  29. Marr I, Farmer K, Krüger K. Evidence for Right-Sided Horses Being More Optimistic than Left-Sided Horses.. Animals (Basel) 2018 Nov 22;8(12).
    doi: 10.3390/ani8120219pmc: PMC6315450pubmed: 30469484google scholar: lookup
  30. Brooks DE, Komàromy AM, Källberg ME. Comparative retinal ganglion cell and optic nerve morphology.. Vet Ophthalmol 1999;2(1):3-11.
    doi: 10.1046/j.1463-5224.1999.00047.xpubmed: 11397238google scholar: lookup
  31. Siniscalchi M, Padalino B, Aubé L, Quaranta A. Right-nostril use during sniffing at arousing stimuli produces higher cardiac activity in jumper horses.. Laterality 2015;20(4):483-500.
    doi: 10.1080/1357650X.2015.1005629pubmed: 25635853google scholar: lookup
  32. Kim D, Carlson JN, Seegal RF, Lawrence DA. Differential immune responses in mice with left- and right-turning preference.. J Neuroimmunol 1999 Jan 1;93(1-2):164-71.
    doi: 10.1016/s0165-5728(98)00222-7pubmed: 10378880google scholar: lookup
  33. Quaranta A, Siniscalchi M, Frate A, Vallortigara G. Paw preference in dogs: relations between lateralised behaviour and immunity.. Behav Brain Res 2004 Aug 31;153(2):521-5.
    doi: 10.1016/j.bbr.2004.01.009pubmed: 15265650google scholar: lookup
  34. Quaranta A, Siniscalchi M, Frate A, Iacoviello R, Buonavoglia C, Vallortigara G. Lateralised behaviour and immune response in dogs: relations between paw preference and interferon-gamma, interleukin-10 and IgG antibodies production.. Behav Brain Res 2006 Jan 30;166(2):236-40.
    doi: 10.1016/j.bbr.2005.08.001pubmed: 16159674google scholar: lookup
  35. McGreevy PD, Thomson PC. Differences in motor laterality between breeds of performance horse. Appl. Anim. Behav. Sci. 99, 183–190.
    doi: 10.1016/j.applanim.2005.09.010google scholar: lookup
  36. Rogers LJ. Hand and paw preferences in relation to the lateralized brain.. Philos Trans R Soc Lond B Biol Sci 2009 Apr 12;364(1519):943-54.
    doi: 10.1098/rstb.2008.0225pmc: PMC2666076pubmed: 19064357google scholar: lookup
  37. Austin NP, Rogers LJ. Limb preferences and lateralization of aggression, reactivity and vigilance in feral horses, Equus caballus. Anim. Behav. 83, 239–247.
    doi: 10.1016/j.anbehav.2011.10.033google scholar: lookup
  38. Siniscalchi M, Lusito R, Vallortigara G, Quaranta A. Seeing left- or right-asymmetric tail wagging produces different emotional responses in dogs.. Curr Biol 2013 Nov 18;23(22):2279-2282.
    doi: 10.1016/j.cub.2013.09.027pubmed: 24184108google scholar: lookup
  39. Deesing MJ, Grandin T. Chapter 7 - Behavior genetics of the horse (Equus caballus). In Genetics and the behavior of domestic animals, 2nd edn (eds Grandin T, Deesing MJ), pp. 237–290. San Diego, CA: Academic Press.
  40. Siniscalchi M, Padalino B, Lusito R, Quaranta A. Is the left forelimb preference indicative of a stressful situation in horses?. Behav Processes 2014 Sep;107:61-7.
    doi: 10.1016/j.beproc.2014.07.018pubmed: 25108052google scholar: lookup
  41. Tang AC. A hippocampal theory of cerebral lateralization. In The asymmetrical brain, pp. 42 Cambridge, MA: MIT Press.
  42. De Boyer Des Roches A, Richard-Yris MA, Henry S, Ezzaouïa M, Hausberger M. Laterality and emotions: visual laterality in the domestic horse (Equus caballus) differs with objects' emotional value.. Physiol Behav 2008 Jun 9;94(3):487-90.
    doi: 10.1016/j.physbeh.2008.03.002pubmed: 18455205google scholar: lookup
  43. Farmer K, Krüger K, Byrne RW, Marr I. Sensory laterality in affiliative interactions in domestic horses and ponies (Equus caballus).. Anim Cogn 2018 Sep;21(5):631-637.
    doi: 10.1007/s10071-018-1196-9pmc: PMC6097077pubmed: 29948296google scholar: lookup
  44. Larose C, Richard-Yris MA, Hausberger M, Rogers LJ. Laterality of horses associated with emotionality in novel situations.. Laterality 2006 Jul;11(4):355-67.
    doi: 10.1080/13576500600624221pubmed: 16754236google scholar: lookup
  45. Basile M, Boivin S, Boutin A, Blois-Heulin C, Hausberger M, Lemasson A. Socially dependent auditory laterality in domestic horses (Equus caballus).. Anim Cogn 2009 Jul;12(4):611-9.
    doi: 10.1007/s10071-009-0220-5pubmed: 19283416google scholar: lookup
  46. Smith AV, Proops L, Grounds K, Wathan J, McComb K. Functionally relevant responses to human facial expressions of emotion in the domestic horse (Equus caballus).. Biol Lett 2016 Feb;12(2):20150907.
    doi: 10.1098/rsbl.2015.0907pmc: PMC4780548pubmed: 26864784google scholar: lookup
  47. de Latude M, Demange M, Bec P, Blois-Heulin C. Visual laterality responses to different emotive stimuli by red-capped mangabeys, Cercocebus torquatus torquatus.. Anim Cogn 2009 Jan;12(1):31-42.
    doi: 10.1007/s10071-008-0166-zpubmed: 18566841google scholar: lookup
  48. Hews DK, Castellano M, Hara E. Aggression in females is also lateralized: left-eye bias during aggressive courtship rejection in lizards. Anim. Behav. 68, 1201–1207.
    doi: 10.1016/j.anbehav.2003.11.024google scholar: lookup
  49. Siniscalchi M, Sasso R, Pepe AM, Vallortigara G, Quaranta A. Dogs turn left to emotional stimuli.. Behav Brain Res 2010 Apr 2;208(2):516-21.
    doi: 10.1016/j.bbr.2009.12.042pubmed: 20060016google scholar: lookup
  50. Krueger K, Farmer K, Byrne R. The use of sensory laterality for indicating emotional and cognitive reactions on environmental stimuli in animals [Die sensorische Lateralität als Indikator für emotionale und kognitive Reaktionen auf Umweltreize beim Tier]. In Current research in applied ethology [aktuelle arbeiten zur artgemäßen tierhaltung, pp. 13–23. Darmstadt, Germany: KTBL.
  51. Schmidt A, Aurich J, Möstl E, Müller J, Aurich C. Changes in cortisol release and heart rate and heart rate variability during the initial training of 3-year-old sport horses.. Horm Behav 2010 Sep;58(4):628-36.
    doi: 10.1016/j.yhbeh.2010.06.011pubmed: 20600048google scholar: lookup
  52. Gorgasser I, Tichy A, Palme R. Faecal cortisol metabolites in Quarter Horses during initial training under field conditions. Wien. Tierarztl. Monatsschr. 94, 226–230.
  53. Austin NP, Rogers LJ. Lateralization of agonistic and vigilance responses in Przewalski horses (Equus przewalskii). Appl. Anim. Behav. Sci. 151, 43–50.
    doi: 10.1016/j.applanim.2013.11.011google scholar: lookup
  54. Farmer K, Krueger K, Byrne RW. Visual laterality in the domestic horse (Equus caballus) interacting with humans.. Anim Cogn 2010 Mar;13(2):229-38.
    doi: 10.1007/s10071-009-0260-xpubmed: 19618222google scholar: lookup
  55. Hölker S. Typologie der deutschen Pferdehaltung - Eine empirische Studie mittels Two-Step-Clusteranalyse. Berichte Über Landwirtsch. - Z. Für Agrarpolit. Landwirtsch. 94, 1–24.
    doi: 10.12767/buel.v94i3.130google scholar: lookup
  56. Möstl E, Palme R. Hormones as indicators of stress.. Domest Anim Endocrinol 2002 Jul;23(1-2):67-74.
    doi: 10.1016/S0739-7240(02)00146-7pubmed: 12142227google scholar: lookup
  57. Eriksson E, Royo F, Lyberg K, Carlsson HE, Hau J. Effect of metabolic cage housing on immunoglobulin A and corticosterone excretion in faeces and urine of young male rats.. Exp Physiol 2004 Jul;89(4):427-33.
    doi: 10.1113/expphysiol.2004.027656pubmed: 15131075google scholar: lookup
  58. Aurich J, Wulf M, Ille N, Erber R, von Lewinski M, Palme R, Aurich C. Effects of season, age, sex, and housing on salivary cortisol concentrations in horses.. Domest Anim Endocrinol 2015 Jul;52:11-6.
    doi: 10.1016/j.domaniend.2015.01.003pubmed: 25700267google scholar: lookup
  59. Krueger K, Marr I, Dobler A, Palme R. Preservation of fecal glucocorticoid metabolites and immunoglobulin A through silica gel drying for field studies in horses.. Conserv Physiol 2019;7(1):coz065.
    doi: 10.1093/conphys/coz065pmc: PMC6821355pubmed: 31687143google scholar: lookup
  60. Flauger B, Krueger K, Gerhards H, Möstl E. Simplified method to measure glucocorticoid metabolites in faeces of horses.. Vet Res Commun 2010 Feb;34(2):185-95.
    doi: 10.1007/s11259-010-9344-ypubmed: 20182914google scholar: lookup
  61. Palme R, Touma C, Arias N, Dominchin MF, Lepschy M. Steroid extraction: get the best out of faecal samples. Wien. Tierarztl. Monatsschr. 100, 238–246.
  62. Palme R, Möstl E, Brem G, Schellander K, Bamberg E. Faecal metabolites of infused 14C-progesterone in domestic livestock. Reprod. Domest. Anim. 32, 199–206.
    doi: 10.1111/j.1439-0531.1997.tb01282.xgoogle scholar: lookup
  63. Hau J, Andersson E, Carlsson HE. Development and validation of a sensitive ELISA for quantification of secretory IgA in rat saliva and faeces.. Lab Anim 2001 Oct;35(4):301-6.
    doi: 10.1258/0023677011911822pubmed: 11669312google scholar: lookup
  64. Peters IR, Calvert EL, Hall EJ, Day MJ. Measurement of immunoglobulin concentrations in the feces of healthy dogs.. Clin Diagn Lab Immunol 2004 Sep;11(5):841-8.
    doi: 10.1128/CDLI.11.5.841-848.2004pmc: PMC515266pubmed: 15358641google scholar: lookup
  65. Yin YJ, Nie CY, Liu WS, Zou Q, Zhai JC, Han HS, Li HP. Non-invasive determination of the immune physiological state of reindeer (Rangifer tarandus) in the Greater Khingan Mountains, China.. Genet Mol Res 2015 Jun 18;14(2):6664-73.
    doi: 10.4238/2015.June.18.9pubmed: 26125874google scholar: lookup
  66. Wittling W, Pflüger M. Neuroendocrine hemisphere asymmetries: salivary cortisol secretion during lateralized viewing of emotion-related and neutral films.. Brain Cogn 1990 Nov;14(2):243-65.
    doi: 10.1016/0278-2626(90)90032-Jpubmed: 2285516google scholar: lookup
  67. Engler H, Dawils L, Hoves S, Kurth S, Stevenson JR, Schauenstein K, Stefanski V. Effects of social stress on blood leukocyte distribution: the role of alpha- and beta-adrenergic mechanisms.. J Neuroimmunol 2004 Nov;156(1-2):153-62.
    doi: 10.1016/j.jneuroim.2004.08.005pubmed: 15465606google scholar: lookup
  68. Koolhaas JM, Bartolomucci A, Buwalda B, de Boer SF, Flügge G, Korte SM, Meerlo P, Murison R, Olivier B, Palanza P, Richter-Levin G, Sgoifo A, Steimer T, Stiedl O, van Dijk G, Wöhr M, Fuchs E. Stress revisited: a critical evaluation of the stress concept.. Neurosci Biobehav Rev 2011 Apr;35(5):1291-301.
    doi: 10.1016/j.neubiorev.2011.02.003pubmed: 21316391google scholar: lookup
  69. Heird JC, Lokey CE, Cogan DC. Repeatability and comparison of two maze tests to measure learning ability in horses. Appl. Anim. Behav. Sci. 16, 103–119.
    doi: 10.1016/0168-1591(86)90103-6google scholar: lookup
  70. Mendl M. Performing under pressure: stress and cognitive function. Appl. Anim. Behav. Sci. 65, 221–244.
    doi: 10.1016/S0168-1591(99)00088-Xgoogle scholar: lookup
  71. Rivera E, Benjamin S, Nielsen B, Shelle J, Zanella AJ. Behavioral and physiological responses of horses to initial training: the comparison between pastured versus stalled horses. Appl. Anim. Behav. Sci. 78, 235–252.
    doi: 10.1016/S0168-1591(02)00091-6google scholar: lookup
  72. Søndergaard E, Ladewig J. Group housing exerts a positive effect on the behaviour of young horses during training. Appl. Anim. Behav. Sci. 87, 105–118.
    doi: 10.1016/j.applanim.2003.12.010google scholar: lookup
  73. Visser EK, Ellis AD, Van Reenen CG. The effect of two different housing conditions on the welfare of young horses stabled for the first time. Appl. Anim. Behav. Sci. 114, 521–533.
    doi: 10.1016/j.applanim.2008.03.003google scholar: lookup
  74. Rochais C, Henry S, Fureix C, Hausberger M. Investigating attentional processes in depressive-like domestic horses (Equus caballus).. Behav Processes 2016 Mar;124:93-6.
    doi: 10.1016/j.beproc.2015.12.010pubmed: 26739514google scholar: lookup
  75. Rogers LJ. A matter of degree: strength of brain asymmetry and behaviour. Symmetry 9, 57.
    doi: 10.3390/sym9040057google scholar: lookup
  76. Harewood EJ, McGowan CM. Behavioral and physiological responses to stabling in naive horses. J. Equine Vet. Sci. 25, 164–170.
    doi: 10.1016/j.jevs.2005.03.008google scholar: lookup
  77. Palme R. Non-invasive measurement of glucocorticoids: Advances and problems.. Physiol Behav 2019 Feb 1;199:229-243.
    doi: 10.1016/j.physbeh.2018.11.021pubmed: 30468744google scholar: lookup

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  1. Krueger K, Gruentjens T, Hempel E. Wolf contact in horses at permanent pasture in Germany.. PLoS One 2023;18(8):e0289767.
    doi: 10.1371/journal.pone.0289767pubmed: 37561797google scholar: lookup
  2. Żak-Bochenek A, Bajzert J, Sambor D, Siwińska N, Szponar B, Łaczmański Ł, Żebrowska P, Czajkowska A, Karczewski M, Chełmońska-Soyta A. Homeostasis of the Intestinal Mucosa in Healthy Horses-Correlation between the Fecal Microbiome, Secretory Immunoglobulin A and Fecal Egg Count.. Animals (Basel) 2022 Nov 10;12(22).
    doi: 10.3390/ani12223094pubmed: 36428322google scholar: lookup
  3. Schmucker S, Preisler V, Marr I, Krüger K, Stefanski V. Single housing but not changes in group composition causes stress-related immunomodulations in horses.. PLoS One 2022;17(8):e0272445.
    doi: 10.1371/journal.pone.0272445pubmed: 35976860google scholar: lookup
  4. Krueger K, Schwarz S, Marr I, Farmer K. Laterality in Horse Training: Psychological and Physical Balance and Coordination and Strength Rather Than Straightness.. Animals (Basel) 2022 Apr 16;12(8).
    doi: 10.3390/ani12081042pubmed: 35454288google scholar: lookup
  5. Schwarz S, Marr I, Farmer K, Graf K, Stefanski V, Krueger K. Does Carrying a Rider Change Motor and Sensory Laterality in Horses?. Animals (Basel) 2022 Apr 12;12(8).
    doi: 10.3390/ani12080992pubmed: 35454239google scholar: lookup
  6. Baragli P, Scopa C, Felici M, Reddon AR. Horses show individual level lateralisation when inspecting an unfamiliar and unexpected stimulus.. PLoS One 2021;16(8):e0255688.
    doi: 10.1371/journal.pone.0255688pubmed: 34351986google scholar: lookup
  7. Krueger K, Esch L, Farmer K, Marr I. Basic Needs in Horses?-A Literature Review.. Animals (Basel) 2021 Jun 16;11(6).
    doi: 10.3390/ani11061798pubmed: 34208615google scholar: lookup
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