Obstructive pulmonary disease in 18 horses at summer pasture.
- Journal Article
- Bronchoalveolar Lavage
- Chronic Obstructive Pulmonary Disease
- Clenbuterol
- Clinical Findings
- Clinical Pathology
- Clinical Signs
- Clinical Study
- Cytology
- Dexamethasone
- Diagnosis
- Disease
- Disease Diagnosis
- Disease Treatment
- Endoscopy
- Equine Health
- Horses
- Pasture
- Pulmonary Health
- Respiratory Disease
- Veterinary Care
- Veterinary Medicine
Summary
The research article focuses on the examination of 18 instances of obstructive pulmonary disease in horses that are consistently kept in summer pasture. It discusses the symptoms, possible causes, and potential treatments for the condition.
Research Overview
The research looks into 18 cases of horses displaying obstructive pulmonary disease symptoms such as coughing, wheezing, and expiratory dyspnoea while they remained in grassy areas without access to hay or straw for a minimum of two consecutive years. In nine cases, the disease’s occurrence showed a seasonal pattern with symptoms appearing during April and May.
- It was noted that severe dyspnoea affected eleven of these horses, giving bouts of intense difficulty breathing.
- It was also revealed that chronic obstructive pulmonary disease was present in eleven horses, while two were affected by idiopathic headshaking, a condition without a known cause.
Diagnostic Procedure
Diagnostic procedures were carried out using endoscopy and cytological examinations of tracheal aspirates and bronchoalveolar lavage fluid, which showed evidence of lower airway inflammation and a rise in neutrophils, immune cells that respond to inflammation.
Treatment and Management
Various attempts were made to manage and treat this condition. For instance, attempts to control the disease by moving the horses into a stable proved effective in only two out of 16 cases. Use of the drug clenbuterol was beneficial in seven out of 15 cases.
- Interestingly, the most effective treatment revealed through this study was a combination of systemic dexamethasone or oral prednisolone with clenbuterol, implying a need for a multi-modal approach to treatment.
The results of this study contribute to the understanding of obstructive pulmonary disease in horses, highlighting the importance of early detection, accurate diagnosis, and appropriate treatment.
Cite This Article
Publication
Researcher Affiliations
- Bell Equine Veterinary Clinic, Mereworth, Maidstone, Kent.
MeSH Terms
- Administration, Oral
- Animals
- Anti-Inflammatory Agents / administration & dosage
- Anti-Inflammatory Agents / therapeutic use
- Bronchoalveolar Lavage Fluid / cytology
- Bronchodilator Agents / administration & dosage
- Bronchodilator Agents / therapeutic use
- Clenbuterol / administration & dosage
- Clenbuterol / therapeutic use
- Dexamethasone / administration & dosage
- Dexamethasone / therapeutic use
- Drug Therapy, Combination
- Female
- Horse Diseases / diagnosis
- Horse Diseases / drug therapy
- Horse Diseases / epidemiology
- Horses
- Incidence
- Lung Diseases, Obstructive / drug therapy
- Lung Diseases, Obstructive / epidemiology
- Lung Diseases, Obstructive / veterinary
- Male
- Neutropenia / pathology
- Prednisolone / administration & dosage
- Prednisolone / therapeutic use
- Seasons
- Trachea / pathology
Citations
This article has been cited 4 times.- Wenzel CJ, Mochal-King CA, Eddy AL, Bowser JE, Wills RW, Jumper WI, Claude A, Swiderski CE. Surgical Assessment and Post-Operative Complications Following Video-Assisted Thoracoscopic Surgery (VATS) of Horses with Severe Equine Pasture Asthma During Asthma Exacerbation and Remission. Animals (Basel) 2025 Aug 4;15(15).
- Mańkowska A, Witkowska D. The Most Common Environmental Risk Factors for Equine Asthma-A Narrative Review. Animals (Basel) 2024 Jul 14;14(14).
- Mainguy-Seers S, Lavoie JP. Glucocorticoid treatment in horses with asthma: A narrative review. J Vet Intern Med 2021 Jul;35(4):2045-2057.
- Couetil L, Cardwell JM, Leguillette R, Mazan M, Richard E, Bienzle D, Bullone M, Gerber V, Ivester K, Lavoie JP, Martin J, Moran G, Niedźwiedź A, Pusterla N, Swiderski C. Equine Asthma: Current Understanding and Future Directions. Front Vet Sci 2020;7:450.