Occupational exposure to isoflurane during anaesthesia induction with standard and scavenging double masks in dogs, pigs and ponies.
Abstract: Induction of anaesthesia using a face mask may cause workplace pollution with anaesthetics. The aim of this study was to compare the effect of the use of a standard versus a scavenging double face mask on isoflurane pollution during induction of anaesthesia in experimental animals: six dogs, 12 pigs and five ponies. Pigs were anaesthetized only once using either mask type randomly (n = 6). Dogs and ponies were anaesthetized twice, using different mask types for each occasion in a random order with at least 14 days between experiments. The masks were attached to a Bain breathing system (dogs and pigs) or to a circle system (ponies) using a fresh gas flow of 300 or 50 mL/kg/min, respectively, with 5% vaporizer dial setting. Isoflurane concentrations were measured in the anaesthetist's breathing zone using an infrared photoacoustic spectrometer. The peak isoflurane concentrations (pollution) during baseline and induction periods were compared with Wilcoxon test in all species, and values between the mask types were compared with either Wilcoxon (ponies and dogs) or Mann-Whitney tests (pigs) (P < 0.05). Pollution was higher during induction when compared with baseline regardless of the mask type used but it was only statistically significant in dogs and pigs. Pollution was lower during induction with double versus single masks but it was only significant in pigs. Despite the lack of statistical significance, large and consistent differences were noted in all species, hence using scavenging masks is recommended to reduce isoflurane workplace pollution.
Publication Date: 2011-05-17 PubMed ID: 21586515DOI: 10.1258/la.2011.010128Google Scholar: Lookup
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Summary
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This study explores the workplace pollution caused by the induction of anaesthesia on different animals using a standard face mask versus a scavenging double face mask. The scientists found notable differences in the level of the anaesthetic, isoflurane, in the air regardless of the type of mask used, with scavenging masks being recommended to reduce pollution.
Research Objective and Methodology
- The study aimed to assess the impact of a standard mask and a scavenging double mask on the presence of isoflurane in the surrounding air during anesthesia induction in specific animals like dogs, pigs and ponies.
- The experiments involved six dogs, twelve pigs, and five ponies. Dogs and ponies underwent anaesthesia twice – each time with a different mask, while pigs were only anaesthetized once.
- Different fresh gas flow rates and systems were used for animals of different size; The masks were attached to a Bain breathing system for dogs and pigs, while a circle system was used for ponies.
- Isoflurane concentrations in the area immediately surrounding the anaesthetist were measured using an infrared photoacoustic spectrometer.
- Data was statistically analyzed for both the peak isoflurane levels during baseline and induction periods and the different mask types using Wilcoxon or Mann-Whitney tests.
Research Findings
- The research found that the pollution levels were higher during the induction period in comparison to the baseline for both types of masks. This increase was statistically significant for dogs and pigs.
- Isoflurane pollution was lower when induction was performed with the double mask in comparison to the single mask. This was statistically significant only in pigs.
- Even though the decrease in pollution with the use of double masks wasn’t statistically significant in all cases, the team noted a consistent difference across all the species studied.
Conclusion
- The study concluded that induction of anaesthesia can cause workplace pollution with isoflurane.
- While the use of double masks helps reduce this pollution, the extent of reduction wasn’t significant in all species.
- Despite this, the consistent presence of a difference across all species suggests that scavenging masks could be a safer option to minimize workplace pollution.
Cite This Article
APA
Säre H, Ambrisko TD, Moens Y.
(2011).
Occupational exposure to isoflurane during anaesthesia induction with standard and scavenging double masks in dogs, pigs and ponies.
Lab Anim, 45(3), 191-195.
https://doi.org/10.1258/la.2011.010128 Publication
Researcher Affiliations
- Clinical Department for Companion Animals and Horses, Division of Anaesthesiology and Perioperative Intensive Care, University of Veterinary Medicine Vienna, Vienna, Austria. heli.saere@vetmeduni.ac.at
MeSH Terms
- Air Pollution, Indoor / prevention & control
- Anesthesia, Inhalation / methods
- Anesthesia, Inhalation / veterinary
- Anesthetics, Inhalation / analysis
- Anesthetics, Inhalation / toxicity
- Animals
- Dogs
- Female
- Gas Scavengers / veterinary
- Horses
- Isoflurane / analysis
- Isoflurane / toxicity
- Male
- Masks / veterinary
- Occupational Exposure / prevention & control
- Random Allocation
- Swine
Citations
This article has been cited 6 times.- Winner EM, Beisl M, Gumbert S, Härtel H, Kaiser J, Wernecke A, Senf S, Zablotski Y, Ritzmann M, Zöls S. Implementation of piglet castration under inhalation anaesthesia on farrowing farms.. Porcine Health Manag 2022 May 17;8(1):20.
- Figueiredo DBS, Aun AG, Lara JR, Garofalo NA, Teixeira-Neto FJ, Braz LG, Braz MG. Measurement of anesthetic pollution in veterinary operating rooms for small animals: Isoflurane pollution in a university veterinary hospital.. Braz J Anesthesiol 2021 Sep-Oct;71(5):517-522.
- Ambar N, Eshar D, Shrader TC, Beaufrère H. Anesthetic Effects of Intramuscular Alfaxalone-Ketamine in Naked Mole Rats (Heterocephalus glaber).. J Am Assoc Lab Anim Sci 2020 Sep 1;59(5):539-545.
- Eshar D, Beaufrère H. Anesthetic Effects of Alfaxalone-Ketamine, Alfaxalone-Ketamine-Dexmedetomidine, and Alfaxalone-Butorphanol-Midazolam Administered Intramuscularly in Five‑striped Palm Squirrels (Funambulus pennantii).. J Am Assoc Lab Anim Sci 2020 May 29;59(4):384-92.
- Browning GR, Eshar D, Beaufrere H. Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (Cynomys ludovicianus).. J Am Assoc Lab Anim Sci 2019 Jan 1;58(1):50-57.
- Fox L, Snyder LB, Mans C. Comparison of Dexmedetomidine-Ketamine with Isoflurane for Anesthesia of Chinchillas (Chinchilla lanigera).. J Am Assoc Lab Anim Sci 2016;55(3):312-6.
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