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International journal of cancer1975; 15(1); 39-47; doi: 10.1002/ijc.2910150106

Occurrence of nervous-tissue tumors in cattle, horses, cats and dogs.

Abstract: From 11 North American veterinary university hospitals and clinics, 248 animals were a confirmed diagnosis of nervous-tissue tumor were identified; 7 tumors were found in cattle, 28 in horses, 14 in cats, 199 in dogs, and none in other species. Tumors were divided for analysis into three categories-glial, meningeal, and peripheral nerve. In cattle and horses, all tumors involved peripheral nerves, the risk of which, in horses, reached a plateau at 4-6 years of age and remained constant thereafter. In cats, the tumors were equally distributed among the three tumor categories whereas, in dogs, twice as many glial tumors as meningeal and peripheral nerve tumors were found. The risk for glial tumors in dogs reached a peak at 10-14 years of age, for meningeal at 7-9 years, and for peripheral nerve at 2-3 and 7-9 years. Three canine breeds-English bulldog, boxer, and Boston terrier-had an excessive rish of glial tumors. Except for an excess of skin tumors in dogs with peripheral nerve tumors, there was no unusual occurrence with second primary neoplasms for any species. There was no detectable predisposition by sex for any of the categories of nervous-tissue tumors among any of the four species. The role of genetic abnormalities associated with nervous-tissue tumors and other etiologic factors (e.g., chronic hypoxia) may be clarified by further studies involving canine breeds of "bulldog" ancestry.
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Publication Date: 1975-01-15 PubMed ID: 165149DOI: 10.1002/ijc.2910150106Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study examines the occurrence of nervous-tissue tumors in various animal species, mainly focusing on cattle, horses, cats and dogs. Researchers analyzed cases of these tumors obtained from 11 North American veterinary university hospitals and clinics and categorized them into three groups – glial, meningeal, and peripheral nerve tumors.

Methodology And Findings

  • The researchers collectively recorded 248 cases of confirmed nervous-tissue tumors from veterinary university hospitals and clinics across North America.
  • These cases were broken down into cattle (7), horses (28), cats (14), and dogs (199), with no nervous-tissue tumors being recorded in other species.
  • The tumours were categorized into three main types for analysis purposes: glial (brain-specific), meningeal (related to the meninges of the brain), and peripheral nerve tumours.

Species-specific Observations

  • In cattle and horses, all tumors were found to involve peripheral nerves.
  • In horses, the risk of peripheral nerve tumors appeared to plateau between ages 4-6 and stayed consistent thereafter.
  • Cats showed an equal distribution of tumours among the three categories.
  • Dogs, however, had twice as many glial tumors as they had meningeal and peripheral nerve tumors.
  • Within canines, the risk for different types of tumours peaked at different ages, with glial tumors peaking at 10-14 years, meningeal tumors at 7-9 years, and peripheral nerve tumors at 2-3 and then again at 7-9 years.
  • The English bulldog, boxer, and Boston terrier breeds were identified as having an excessive risk of glial tumours.
  • Aside from an excess of skin tumors found in dogs with peripheral nerve tumors, there wasn’t an unusual occurrence of secondary primary neoplasms in any species.

Genetic and Etiologic Factors

  • No clear predisposition by sex was detected for any categories of nervous-tissue tumors among the four species studied.
  • The researchers suggest that further study into canine breeds of “bulldog” ancestry could help clarify the role of genetic abnormalities associated with nervous-tissue tumors and other causative factors, such as chronic hypoxia.

Cite This Article

APA
Hayes HM, Priester WA, Pendergrass TW. (1975). Occurrence of nervous-tissue tumors in cattle, horses, cats and dogs. Int J Cancer, 15(1), 39-47. https://doi.org/10.1002/ijc.2910150106

Publication

International journal of cancer
ISSN: 0020-7136
NlmUniqueID: 0042124
Country: United States
Language: English
Volume: 15
Issue: 1
Pages: 39-47

Researcher Affiliations

Hayes, H M
    Priester, W A
      Pendergrass, T W

        MeSH Terms

        • Age Factors
        • Animals
        • Astrocytoma / epidemiology
        • Astrocytoma / veterinary
        • Cat Diseases / epidemiology
        • Cats
        • Cattle
        • Cattle Diseases / epidemiology
        • Dog Diseases / epidemiology
        • Dogs
        • Ependymoma / epidemiology
        • Ependymoma / veterinary
        • Glioma / epidemiology
        • Glioma / veterinary
        • Horse Diseases / epidemiology
        • Horses
        • Medulloblastoma / epidemiology
        • Medulloblastoma / veterinary
        • Meningioma / epidemiology
        • Meningioma / veterinary
        • Neoplasms, Multiple Primary
        • Neoplasms, Nerve Tissue / epidemiology
        • Neoplasms, Nerve Tissue / veterinary
        • Sex Factors
        • Species Specificity
        • United States

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