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The Canadian veterinary journal = La revue veterinaire canadienne2020; 61(2); 181-186;

Ovarian histopathology, pre- and post-operative endocrinological analysis and behavior alterations in 27 mares undergoing bilateral standing laparoscopic ovariectomy.

Abstract: Determining if ovariectomy will abolish unwanted behaviors can be challenging in mares without ultrasonographic ovarian abnormalities and/or endocrine values not consistent with a granulosa cell tumor. The objective of the study was to identify mares that have a positive improvement in unwanted behaviors after elective standing laparoscopic ovariectomy and to determine if the change is associated with any pre- and post-operative endocrine profiles and/or with ovarian histological findings. During the study period 27 mares underwent a bilateral standing laparoscopic ovariectomy. Pre- and post-operative questionnaires and endocrine profiles, along with ovarian histopathology were performed and data were analyzed. Eighty-nine percent of clients were satisfied with the change in behavior after surgery. There were no significant associations between specific elevated hormones or absent luteal tissue with any specific unwanted behaviors. Pre-operative endocrine values were not predictive of post-operative owner satisfaction but bilateral ovariectomy for the treatment of unwanted behaviors in mares had a high likelihood of achieving owner satisfaction. Déterminer si une ovariectomie éliminera les comportements non-désirés peut représenter un défi chez les juments sans anomalie ovarienne détectable par échographie et/ou ayant des valeurs endocrines non cohérentes avec une tumeur des cellules de la granulosa. L’objectif de la présente étude était d’identifier les juments avec une amélioration positive des comportements non-désirés à la suite d’une ovariectomie élective par laparoscopie en position debout et de déterminer si le changement était associé avec un quelconque profil endocrinien pré- et post-opération et/ou avec des trouvailles histologiques dans les ovaires. Durant la période d’étude 27 juments ont été soumises à une ovariectomie laparoscopique bilatérale en position debout. Des questionnaires pré- et post-opération ainsi que des profils endocriniens et des analyses histopathologiques des ovaires furent réalisés et les données analysées. Quatre-vingt-neuf pourcents des clients étaient satisfaits avec le changement dans le comportement après la chirurgie. Il n’y avait pas d’association significative entre des niveaux élevés d’hormones spécifiques ou l’absence de tissu lutéal et des comportements non-désirés spécifiques. Les valeurs endocrines pré-opération n’étaient pas prédictives de la satisfaction post-opération des propriétaires mais l’ovariectomie bilatérale pour le traitement de comportements non-désirés chez les juments avait un grand potentiel d’obtenir la satisfaction du propriétaire.(Traduit par D Serge Messier).
Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.
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Publication Date: 2020-02-06 PubMed ID: 32020939PubMed Central: PMC6973214
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the effectiveness of laparoscopic ovariectomy in altering unwanted behaviors in mares and its relation to pre- and post-operative endocrine profiles and ovarian histological findings. It finds that this procedure has a high chance of achieving owner satisfaction, despite the absence of significant correlation between certain hormones or absent luteal tissue and specific unwanted behaviors.

Research Methodology

  • The research was carried out on 27 mares that underwent bilateral standing laparoscopic ovariectomy, a procedure which entails the surgical removal of the ovaries while the animal is standing.
  • Pre- and post-operative questionnaires were administered to collect data on the mares’ behaviors. Additionally, endocrine profiles of the mares were obtained both before and after the operation to assess hormone levels.
  • The researchers also conducted a histopathological study on the detached ovaries, a laboratory examination of tissues under the microscope to detect any abnormality or disease.

Research Findings

  • The findings from this study suggested that the surgical procedure led to improvements in the behavior of the mares as reported by the owners. This was evidenced by the fact that 89% of the study participants reported satisfaction with the changes in behavior post-surgery.
  • In regard to the links between hormones or luteal tissues and certain behaviors, no significant associations were observed. The luteal tissue is part of the ovarian structure and produces the hormone progesterone. Absence of luteal tissue implies non-production of this hormone.
  • Moreover, the study found that pre-operative endocrine levels couldn’t predict the owners’ post-operative satisfaction, refuting any potential assertions that pre-operative hormone levels could act as a reliable indicator for successful behavioral changes post-surgery.
  • Overall, the research suggests that bilateral laparoscopic ovariectomy is a viable solution for mitigating unwanted behaviors in mares. This is based on the high rate of owner satisfaction post-surgery, despite the lack of a clear-cut relationship between specific elevated hormones or absent luteal tissue and unwanted behaviours.

Cite This Article

APA
Devick IF, Leise BS, McCue PM, Rao S, Hendrickson DA. (2020). Ovarian histopathology, pre- and post-operative endocrinological analysis and behavior alterations in 27 mares undergoing bilateral standing laparoscopic ovariectomy. Can Vet J, 61(2), 181-186.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 61
Issue: 2
Pages: 181-186

Researcher Affiliations

Devick, Ian F
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).
Leise, Britta S
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).
McCue, Patrick M
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).
Rao, Sangeeta
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).
Hendrickson, Dean A
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA (Devick, McCue, Rao, Hendrickson); Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA (Leise).

MeSH Terms

  • Animals
  • Female
  • Granulosa Cell Tumor / veterinary
  • Horse Diseases / surgery
  • Horses
  • Laparoscopy / veterinary
  • Ovarian Neoplasms / veterinary
  • Ovariectomy / veterinary
  • Postoperative Period

Conflict of Interest Statement

The authors declare no conflict of interest related to this report.

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Citations

This article has been cited 4 times.
  1. Dolin A, Schweiger P, Waselau M, Egerbacher M, Walter I. Immunohistochemical markers for equine granulosa cell tumors: a pilot study. J Equine Sci 2023 Jun;34(2):37-46.
    doi: 10.1294/jes.34.37pubmed: 37405069google scholar: lookup
  2. Straticò P, Guerri G, Palozzo A, Varasano V, Petrizzi L. Current Use of Equine Laparoscopy in Urogenital Disorders: A Scoping Review of the Literature from 2000 to 2021. Vet Sci 2022 Jan 22;9(2).
    doi: 10.3390/vetsci9020041pubmed: 35202295google scholar: lookup
  3. Devick IF, Hendrickson DA. Effects of Leaving Amputated Ovaries Intra-Abdominally during Elective Bilateral Standing Laparoscopic Ovariectomy in Equids. Animals (Basel) 2021 Jan 18;11(1).
    doi: 10.3390/ani11010232pubmed: 33477730google scholar: lookup
  4. Wolf N, Hahn JA, Walter I, Zablotski Y, Zerbe H, Witte TS. Pathohistological Findings after Bilateral Ovariectomy in Mares with Behavioral Problems. Animals (Basel) 2024 Oct 8;14(19).
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