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Home / Equine Research Bank / Res Vet Sci / Ozone therapy in veterinary medicine: A review.
Research in veterinary science2020; 130; 240-246; doi: 10.1016/j.rvsc.2020.03.026

Ozone therapy in veterinary medicine: A review.

Abstract: Ozone (O) is a triatomic form of oxygen. As O rapidly dissociates into water and releases a reactive form of oxygen that may oxidize cells, the gas mixture of O/O is used in medicine. ATP is widely available for cellular activity. O can be administered via the systemic and local routes. Although O is known as one of the most powerful oxidants, it also promotes antioxidant enzymes. Additionally, it stimulates some of the cells of the immune system and inactivates pathogens, including bacteria, fungi, yeasts, protozoa, and viruses. Owing to these activities, O is used to improve several diseases, both in human and in veterinary medicine. Considering the wide scope of O application, the aim of this review was to reiterate the mechanisms of action of O and its utilization in different mammalian species (bovine, ovine-caprine, equine, canine, porcine).
Copyright © 2020 Elsevier Ltd. All rights reserved.
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Publication Date: 2020-03-25 PubMed ID: 32234614DOI: 10.1016/j.rvsc.2020.03.026Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article reviews the use of ozone therapy in treating various diseases in different mammal species in veterinary medicine.

Overview of Ozone Therapy

Ozone (O) is a triatomic form of oxygen. In the context of medicine, a gas mixture of ozone and oxygen is used due to ozone’s ability to rapidly dissociate into water while releasing a reactive form of oxygen that has the potential to oxidize cells. This unique characteristic enables ozone to be widely used in medical practices both for humans and animals.

  • The dissociated oxygen form is known to provide ATP, an energy source for cellular activities. This feature explains why ozone can be efficiently delivered systemically or locally to the patients.
  • Despite its powerful oxidant properties, ozone surprisingly promotes antioxidant enzymes. This dual-role contributes to the regulation and balance of oxidative stress within the body.
  • In addition, ozone shows promising potential in stimulating immune cells and neutralizing various pathogens such as bacteria, fungi, yeasts, protozoa, and viruses. This underlines ozone’s role in immune responses and infectious disease control.

Ozone Therapy in Veterinary Medicine

Ozone therapy has been applied in veterinary medicine to treat a range of diseases across various mammal species.

  • In bovine and ovine-caprine species, ozone therapy is used to improve their health condition which ultimately enhances productivity.
  • In equine medicine, ozone is utilized in both prevention and treatment of diseases, showing particularly effective performance in respiratory and joint diseases.
  • The use of ozone therapy in dogs has proved to effectively support the immune system and fight against infectious diseases.
  • Similar to the previous species, ozone application in porcine medicine aids in overall illness prevention and treatment, contributing to improved well-being and increased growth.

Conclusion of the Review

In conclusion, the review highlights the beneficial effects of ozone therapy in veterinary medicine. Although several findings support its use, further research in this field is required for better understanding and potentially more effective applications of ozone in animal health.

Cite This Article

APA
Sciorsci RL, Lillo E, Occhiogrosso L, Rizzo A. (2020). Ozone therapy in veterinary medicine: A review. Res Vet Sci, 130, 240-246. https://doi.org/10.1016/j.rvsc.2020.03.026

Publication

Research in veterinary science
ISSN: 1532-2661
NlmUniqueID: 0401300
Country: England
Language: English
Volume: 130
Pages: 240-246
PII: S0034-5288(20)30056-4

Researcher Affiliations

Sciorsci, R L
  • Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010 Valenzano, BA, Italy. Electronic address: raffaeleluigi.sciorsci@uniba.it.
Lillo, E
  • Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010 Valenzano, BA, Italy.
Occhiogrosso, L
  • Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010 Valenzano, BA, Italy.
Rizzo, A
  • Department of Veterinary Medicine, University of Bari Aldo Moro, S.P. per Casamassima km. 3, 70010 Valenzano, BA, Italy.

MeSH Terms

  • Animals
  • Antioxidants
  • Cattle
  • Cattle Diseases / drug therapy
  • Dog Diseases / drug therapy
  • Dogs
  • Goat Diseases / drug therapy
  • Goats
  • Horse Diseases / drug therapy
  • Horses
  • Oxidants
  • Oxidation-Reduction
  • Ozone / administration & dosage
  • Ozone / therapeutic use
  • Prodrugs
  • Sheep
  • Sheep Diseases / drug therapy
  • Swine
  • Swine Diseases / drug therapy

Citations

This article has been cited 15 times.
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