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Veterinary anaesthesia and analgesia2014; 41(4); 335-345; doi: 10.1111/vaa.12179

Partial intravenous anaesthesia in the horse: a review of intravenous agents used to supplement equine inhalation anaesthesia. Part 1: lidocaine and ketamine.

Abstract: To review the literature with regard to the use of different intravenous agents as supplements to inhalational anaesthesia in horses. These drugs include lidocaine, ketamine, opioids and α2 -agonists. The Part 1 of this review will focus in the use of lidocaine and ketamine. Methods: Pubmed & Web of Science. Search terms: horse, inhalant anaesthesia, balanced anaesthesia, partial intravenous anaesthesia, lidocaine, ketamine. Conclusions: Different drugs and their combinations can be administered systemically in anaesthetized horses, with the aim of reducing the amount of the volatile agent whilst improving the recovery qualities and providing a multimodal analgesic approach. However, full studies as to whether these techniques improve cardiopulmonary status are not always available and potential disadvantages should also be considered.
Publication Date: 2014-05-10 PubMed ID: 24815750DOI: 10.1111/vaa.12179Google Scholar: Lookup
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  • Journal Article
  • Review

Summary

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The research article is a review of various intravenous agents used to supplement inhalation anaesthesia in horses, with a particular focus on lidocaine and ketamine.

Objective of the Review

  • The review aims to evaluate the use of different intravenous drugs as supplements to inhalational anaesthesia in horses.
  • An important focus of this paper is understanding the effectiveness and potential downside of these supplemental agents, with specific emphasis on lidocaine and ketamine.

Methodology

  • The authors conducted a literature review of papers available in databases such as PubMed and Web of Science.
  • Specific search terms were used to obtain relevant literature, including “horse”, “inhalant anaesthesia”, “balanced anaesthesia”, “partial intravenous anaesthesia”, “lidocaine”, and “ketamine”.

Findings

  • They discovered that varying drugs and their combinations could be administered systematically in anesthetized horses.
  • The main goal here is to decrease the dosage of volatile agents, therefore improving the recovery and adding a multimodal analgesic approach—multiple methods used in combination to relieve pain.

Limitations

  • The study identifies a few drawbacks and limitations of the current research body.
  • There is an insufficient number of studies that fully explore whether these supplemental techniques actually help improve the horses’ cardiopulmonary status—the functioning of heart and lung systems.
  • It is also noted that potential disadvantages of using such intravenous agents should be taken into consideration.

Conclusion

  • Overall, though different intravenous agents appear to be a promising supplement to horse anesthesia, more research is needed to establish their efficacy, benefits and potential drawbacks, particularly in terms of improving cardiopulmonary status.

Cite This Article

APA
Gozalo-Marcilla M, Gasthuys F, Schauvliege S. (2014). Partial intravenous anaesthesia in the horse: a review of intravenous agents used to supplement equine inhalation anaesthesia. Part 1: lidocaine and ketamine. Vet Anaesth Analg, 41(4), 335-345. https://doi.org/10.1111/vaa.12179

Publication

ISSN: 1467-2995
NlmUniqueID: 100956422
Country: United States
Language: English
Volume: 41
Issue: 4
Pages: 335-345

Researcher Affiliations

Gozalo-Marcilla, Miguel
  • Department of Surgery and Anaesthesia of Domestic Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Gasthuys, Frank
    Schauvliege, Stijn

      MeSH Terms

      • Anesthesia, Inhalation / veterinary
      • Anesthesia, Intravenous / methods
      • Anesthesia, Intravenous / veterinary
      • Anesthetics, Dissociative / administration & dosage
      • Anesthetics, Dissociative / pharmacology
      • Anesthetics, Local / administration & dosage
      • Anesthetics, Local / pharmacology
      • Animals
      • Horses
      • Ketamine / administration & dosage
      • Ketamine / pharmacology
      • Lidocaine / administration & dosage
      • Lidocaine / pharmacology

      Citations

      This article has been cited 8 times.
      1. Murillo C, Weng HY, Weil AB, Kreuzer M, Ko JC. Perioperative Brain Function Monitoring with Electroencephalography in Horses Anesthetized with Multimodal Balanced Anesthetic Protocol Subjected to Surgeries.. Animals (Basel) 2022 Oct 20;12(20).
        doi: 10.3390/ani12202851pubmed: 36290236google scholar: lookup
      2. Rabbogliatti V, Amari M, Brioschi FA, Di Cesare F, Zani DD, De Zani D, Di Giancamillo M, Cagnardi P, Ravasio G. Use of dexmedetomidine repeated subcutaneous administration for balanced anaesthesia in horses.. BMC Vet Res 2022 Jul 11;18(1):269.
        doi: 10.1186/s12917-022-03350-0pubmed: 35818051google scholar: lookup
      3. Gozalo-Marcilla M, Bettschart-Wolfensberger R, Johnston M, Taylor PM, Redondo JI. Data Collection for the Fourth Multicentre Confidential Enquiry into Perioperative Equine Fatalities (CEPEF4) Study: New Technology and Preliminary Results.. Animals (Basel) 2021 Aug 30;11(9).
        doi: 10.3390/ani11092549pubmed: 34573515google scholar: lookup
      4. Kälin I, Henze IS, Ringer SK, Torgerson PR, Bettschart-Wolfensberger R. Comparison of Recovery Quality Following Medetomidine versus Xylazine Balanced Isoflurane Anaesthesia in Horses: A Retrospective Analysis.. Animals (Basel) 2021 Aug 19;11(8).
        doi: 10.3390/ani11082440pubmed: 34438896google scholar: lookup
      5. Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature.. Animals (Basel) 2021 Jun 14;11(6).
        doi: 10.3390/ani11061777pubmed: 34198637google scholar: lookup
      6. Wiederkehr A, Barbarossa A, Ringer SK, Jörger FB, Bryner M, Bettschart-Wolfensberger R. Clinical Randomized Comparison of Medetomidine and Xylazine for Isoflurane Balanced Anesthesia in Horses.. Front Vet Sci 2021;8:603695.
        doi: 10.3389/fvets.2021.603695pubmed: 33959647google scholar: lookup
      7. Morris TB, Lumsden JM, Dunlop CI, Locke V, Sommerauer S, Hurcombe SDA. Clinical Assessment of an Ipsilateral Cervical Spinal Nerve Block for Prosthetic Laryngoplasty in Anesthetized Horses.. Front Vet Sci 2020;7:284.
        doi: 10.3389/fvets.2020.00284pubmed: 32582775google scholar: lookup
      8. Yang X, Wei X, Mu Y, Li Q, Liu J. A review of the mechanism of the central analgesic effect of lidocaine.. Medicine (Baltimore) 2020 Apr;99(17):e19898.
        doi: 10.1097/MD.0000000000019898pubmed: 32332666google scholar: lookup