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Home / Equine Research Bank / Equine Vet J / Penile and preputial squamous cell carcinoma in the horse: a...
Equine veterinary journal2008; 40(6); 533-537; doi: 10.2746/042516408X281171

Penile and preputial squamous cell carcinoma in the horse: a retrospective study of treatment of 77 affected horses.

Abstract: The most common penile and preputial neoplasm in the horse is the squamous cell carcinoma (SCC), but no large surveys of treatment and effects of the grade of the tumour, based on the degree of differentiation, on outcome of affected horses are available. Objective: Analysis of treatment of male horses affected with SCC of the external genitalia and long-term results of treatment. Methods: Seventy-seven cases of SCC were evaluated. Data recorded included treatment, outcome, post operative histopathology and retrospective tumour grading. Results: Treatments included: cryosurgery, excision, partial phallectomy, partial phallectomy and sheath ablation, and en bloc penile and preputial resection with penile retroversion and removal of inguinal lymph nodes. The incidence of recurrence after partial phallectomy was 25.6% (10/39) and following incomplete removal was 17.9% (7/39). The incidence of recurrence after en bloc resection with retroversion was 12.5% (1/8). In horses with confirmed inguinal lymph node metastasis, the incidence of recurrence was 25.0% (1/4). Poorly differentiated SCCs were more likely to metastasise than well differentiated SCCs, and there was a greater chance that the treatment would be unsuccessful. The success of treatment, complete removal and in preventing recurrence of the tumour, of male horses with SCC of the external genitalia was 55.7%. Conclusions: Horses that receive only partial phallectomy for treatment for SCC of the external genitalia have a high incidence of recurrence in contrast to horses that receive an en bloc resection. Tumour grading of SCC can help predict prognosis and guide selection of treatment.
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Publication Date: 2008-05-20 PubMed ID: 18487102DOI: 10.2746/042516408X281171Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article discusses a retrospective study on the treatment of the most prevalent penile and preputial cancer, squamous cell carcinoma (SCC), in horses. It investigates the effects of tumor grading and outlines the observed outcomes.

Objective and Methodology

  • The goal of this study was to examine the treatment and outcomes of male horses affected with SCC of the external genitalia.
  • The researchers gathered data from 77 cases of SCC, noting information such as the course of treatment, results, any observable changes after the operation, and a retrospective grading of the tumor.

Treatments and Outcomes

  • The study reports on various treatment methods: cryosurgery, excision, partial phallectomy (surgical removal of part of the penis), partial phallectomy coupled with sheath ablation, and en bloc penile and preputial resection with penile retroversion (turning inside out) and removal of inguinal (groin) lymph nodes.
  • The recurrence rate of SCC was found to be 25.6% after partial phallectomy and 17.9% following incomplete removal.
  • The rate of recurrence after “en bloc” resection with retroversion was measured at 12.5%, and in cases with confirmed lymph node metastasis, the recurrence was 25.0%.
  • In terms of differentiation, i.e., the degree to which cancer cells resemble normal cells, poorly differentiated SCCs were more prone to spread than well-differentiated ones, increasing the risk for unsuccessful treatments.

Conclusions and Implications

  • The overall success rate in treating and preventing the recurrence of external genitalia SCC in male horses was found to be 55.7%.
  • The study notes that horses that only undergo a partial phallectomy for SCC treatment are more likely to experience recurrence in contrast to those that receive an en bloc resection.
  • Findings suggest that tumor grading of SCC might offer valuable insights towards predicting prognosis and aiding in the selection of effective treatment strategies.

Cite This Article

APA
van den Top JG, de Heer N, Klein WR, Ensink JM. (2008). Penile and preputial squamous cell carcinoma in the horse: a retrospective study of treatment of 77 affected horses. Equine Vet J, 40(6), 533-537. https://doi.org/10.2746/042516408X281171

Publication

Equine veterinary journal
ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 40
Issue: 6
Pages: 533-537

Researcher Affiliations

van den Top, J G B
  • Department of Equine Sciences, Utrecht University, Yalelaan 114, 3584 CM, Utrecht, The Netherlands.
de Heer, N
    Klein, W R
      Ensink, J M

        MeSH Terms

        • Amputation, Surgical / veterinary
        • Animals
        • Carcinoma, Squamous Cell / mortality
        • Carcinoma, Squamous Cell / pathology
        • Carcinoma, Squamous Cell / surgery
        • Carcinoma, Squamous Cell / veterinary
        • Horse Diseases / mortality
        • Horse Diseases / pathology
        • Horse Diseases / surgery
        • Horses
        • Inguinal Canal / surgery
        • Lymph Node Excision / veterinary
        • Lymph Nodes / pathology
        • Lymphatic Metastasis
        • Male
        • Neoplasm Metastasis
        • Neoplasm Recurrence, Local / epidemiology
        • Neoplasm Recurrence, Local / mortality
        • Neoplasm Recurrence, Local / veterinary
        • Neoplasm Staging / veterinary
        • Penile Neoplasms / mortality
        • Penile Neoplasms / pathology
        • Penile Neoplasms / surgery
        • Penile Neoplasms / veterinary
        • Penis / surgery
        • Prognosis
        • Retrospective Studies
        • Treatment Outcome

        Citations

        This article has been cited 14 times.
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