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Equine veterinary journal2010; 42(8); 746-757; doi: 10.1111/j.2042-3306.2010.00290.x

Penile and preputial tumours in the horse: literature review and proposal of a standardised approach.

Abstract: Penile and preputial tumours are not uncommon in the horse, but can cause discomfort and lead to serious complications. Several types of tumour of the male external genitalia have been described. The most common type is the squamous cell carcinoma (SCC), which is found mainly in older horses. Reports of a breed predilection for penile tumour formation are equivocal, but castration, coat colour, poor hygiene and various infectious agents have all been suggested to predispose to the development of some types of tumour (e.g. SCC, papilloma and melanoma). Careful assessment of the primary tumour is an important first step in the design of an optimal treatment protocol. Invasiveness, differentiation grade, tumour size and presence of metastases are all relevant to the decision to pursue additional diagnostic procedures or specific treatment options. To date, no standard protocol has been reported for the approach to penile tumours in the horse and treatments range from minimally invasive therapies (e.g. topical use of 5-fluorouracil) to radical surgical interventions (e.g. en bloc penile and preputial resection with penile retroversion). Completeness of removal of the neoplasm and therefore risk of recurrence is highly dependent on the type of therapy chosen. However, the size and histopathological features of the primary tumour are also important factors with respect to the likelihood of recurrence. This review describes the most common penile and preputial neoplasms in the horse, and outlines a standard protocol aimed at arriving at a specific diagnosis and tailoring the therapeutic approach accordingly.
Publication Date: 2010-11-03 PubMed ID: 21039806DOI: 10.1111/j.2042-3306.2010.00290.xGoogle Scholar: Lookup
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  • Journal Article
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Summary

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This article reviews common genital tumours in horses and proposes a standardised treatment approach. Tumours are prevalent, particularly in older horses, and can cause discomfort and complications. Various factors like age, hygiene, and breed might contribute to tumour development. While treatments range from minor to major surgical interventions, no standard treatment protocol currently exists. The authors suggest that proper assessment of the tumour type, size, and presence of metastases can inform the best treatment approach.

Overview of Genital Tumours in Horses

  • The research article begins by acknowledging that penile and preputial tumours in horses are relatively common, particularly squamous cell carcinoma (SCC), which is most often seen in older horses. It discusses various factors that may contribute to the development of these tumours, including breed, castration, coat colour, poor hygiene, and exposure to certain infectious agents.
  • The article also notes that reports regarding breed predisposition for tumour development are not conclusive, indicating that any horse may be potentially susceptible to these tumours.

Significance of Tumour Assessment

  • The central theme of the research paper is the importance of careful assessment of the primary tumour in determining the optimal treatment protocol. Multiple factors about the tumour, such as how invasive it is, its differentiation grade, size, and the presence of metastases, influence the decision to proceed with additional diagnostic procedures or specific treatment options.
  • The paper Unpacks how the risk of tumour recurrence significantly depends on the type of therapy selected and that important factors like the size and histopathological features of the primary tumour also influence the likelihood of recurrence.

Treatment Approaches and Proposal of a Standardised Approach

  • The paper discusses the wide range of current treatment methods, from minimally invasive therapies like topical use of 5-fluorouracil to more drastic surgical interventions, like the complete removal and retroversion of the penis and prepuce.
  • However, the main contribution of this paper is the proposal of a standardised approach to treating penile tumours in horses. Recognising the absence of a uniform protocol in treating these conditions, the paper suggests a protocol that aims to make specific diagnoses based on careful tumour assessment and consequently tailor the therapeutic approach.

Cite This Article

APA
Van Den Top JG, Ensink JM, Gröne A, Klein WR, Barneveld A, Van Weeren PR. (2010). Penile and preputial tumours in the horse: literature review and proposal of a standardised approach. Equine Vet J, 42(8), 746-757. https://doi.org/10.1111/j.2042-3306.2010.00290.x

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 42
Issue: 8
Pages: 746-757

Researcher Affiliations

Van Den Top, J G B
  • Department of Equine Sciences and Pathobiology, Utrecht University, The Netherlands. j.g.b.vandetop@uu.nl
Ensink, J M
    Gröne, A
      Klein, W R
        Barneveld, A
          Van Weeren, P R

            MeSH Terms

            • Animals
            • Genital Neoplasms, Male / therapy
            • Genital Neoplasms, Male / veterinary
            • Horse Diseases / therapy
            • Horses
            • Male

            Citations

            This article has been cited 12 times.
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