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Placentitis, fetal pneumonia, and abortion due to Rhodococcus equi infection in a Thoroughbred.

Abstract: Rhodococcus equi is a rare cause of equine abortion. This report describes pyogranulomatous placentitis and fetal pneumonia in a case of abortion from a Thoroughbred mare. Numerous Gram-positive coccobacilli were noted histologically within macrophages in placental and pulmonary lesions. Rhodococcus equi was isolated in pure culture from the placenta, lung, liver, kidney, and stomach content. This is the first description of placentitis due to Rhodococcus equi infection in a horse.
Publication Date: 2002-04-10 PubMed ID: 11939338DOI: 10.1177/104063870201400211Google Scholar: Lookup
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  • Journal Article

Summary

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This research paper focuses on a case of equine abortion in a Thoroughbred mare caused by a rare infection from Rhodococcus equi, a bacterium that generally affects foals.

Introduction to the Study

  • The study describes a unique case of equine abortion in a Thoroughbred mare, caused by Rhodococcus equi, a type of bacterium.
  • It’s significant to note that such a cause for abortion is rare among equines, drawing attention to the uniqueness of this case.

Findings from the Case

  • The findings from the case reveal that the mare suffered from pyogranulomatous placentitis and fetal pneumonia.
  • When examining the condition under a microscope, a lot of Gram-positive coccobacilli were found within the macrophages in the placental and lung lesions.

Bacterial Isolation

  • Scientists were able to isolate Rhodococcus equi in pure culture from various parts of the affected mare’s body including the placenta, lung, liver, kidney, and the stomach content.
  • This confirms that this bacterium was undoubtedly the cause of the abortion, as no other pathogen was found.

Significance of the Study

  • What makes this study a significant one is that it’s the first time placentitis due to Rhodococcus equi infection was found in an equine subject, thus adding to the medical literature in the field.

What this Means for Future Research

  • This discovery widens the known effects and implications of equine abortion causes, raising awareness and inciting further research into the effects and possible preventative measures for Rhodococcus equi infections.
  • It could allow for further identification of rare causes for equine abortion as well as the development of more effective equine healthcare practices related to preventative medicine, diagnosis and treatment of such conditions.

Cite This Article

APA
Patterson-Kane JC, Donahue JM, Harrison LR. (2002). Placentitis, fetal pneumonia, and abortion due to Rhodococcus equi infection in a Thoroughbred. J Vet Diagn Invest, 14(2), 157-159. https://doi.org/10.1177/104063870201400211

Publication

ISSN: 1040-6387
NlmUniqueID: 9011490
Country: United States
Language: English
Volume: 14
Issue: 2
Pages: 157-159

Researcher Affiliations

Patterson-Kane, Janet C
  • Livestock Disease Diagnostic Center, Lexington, KY 40511-1280, USA.
Donahue, J Mike
    Harrison, Lenn R

      MeSH Terms

      • Abortion, Veterinary / etiology
      • Abortion, Veterinary / microbiology
      • Actinomycetales Infections / complications
      • Actinomycetales Infections / veterinary
      • Animals
      • Female
      • Fetal Diseases / microbiology
      • Fetal Diseases / veterinary
      • Horse Diseases / microbiology
      • Horse Diseases / pathology
      • Horses
      • Placenta Diseases / microbiology
      • Placenta Diseases / veterinary
      • Pneumonia / etiology
      • Pneumonia / veterinary
      • Pregnancy
      • Rhodococcus equi / isolation & purification
      • Rhodococcus equi / pathogenicity

      Citations

      This article has been cited 2 times.
      1. Li L, Li S, Ma H, Akhtar MF, Tan Y, Wang T, Liu W, Khan A, Khan MZ, Wang C. An Overview of Infectious and Non-Infectious Causes of Pregnancy Losses in Equine. Animals (Basel) 2024 Jul 2;14(13).
        doi: 10.3390/ani14131961pubmed: 38998073google scholar: lookup
      2. Zhong L, Yan Y, Chen L, Sun N, Li H, Wang Y, Liu H, Jia Y, Lu Y, Liu X, Zhang Y, Guo H, Wang X. Nanopore-based metagenomics analysis reveals microbial presence in amniotic fluid: A prospective study. Heliyon 2024 Mar 30;10(6):e28163.
        doi: 10.1016/j.heliyon.2024.e28163pubmed: 38545162google scholar: lookup