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Journal of equine veterinary science2019; 80; 16-19; doi: 10.1016/j.jevs.2019.06.012

Plasma Apelin Concentration in Exercised Horses: Preliminary Study.

Abstract: Physical effort is one of the key aspects of keeping horses in good condition. The condition of the animal is reflected by multiple blood parameters. The newly discovered cytokine-apelin can pose one of them, however, so far, has not been studied in the horse population. Apelin is produced by adipocytes and myocytes and plays an important role in the energy metabolism of the body through the influence, for example, on the process of adipogenesis and lipolysis. The aim of this study was to investigate if physical effort of various intensity affects the plasma concentration of apelin in horses. The study involved 20 purebred Arabian horses divided into two groups. The first group included 10 race horses, aged 3 years, and second group included 10 horses aged from 6 to 12 years, used in endurance rides. Blood samples were collected from each horse at rest and after exercise. The concentrations of apelin, lactic acid, cortisol, uric acid (UA), triacylglycerols, total plasma protein, and glucose were determined in plasma samples. Race training sessions induced significant decreases in plasma apelin concentrations (P < .05). In endurance horses, significant correlations were found only between exercise-induced changes of apelin and cortisol (r = 0.55) and apelin and UA (r = 0.67) concentrations. In conclusion, the concentration of apelin in equine plasma decreases in response to short-time exercise unlike endurance exercise. Blood plasma apelin concentration determined at rest is lower in long-time regularly trained horses than in the ones at the beginning of their training process.
Publication Date: 2019-07-03 PubMed ID: 31443827DOI: 10.1016/j.jevs.2019.06.012Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research focuses on examining the impact of varying intensities of physical exercise on the plasma apelin concentration in horses. It additionally investigates the effects of regular training on resting apelin levels in horses.

Research Objectives and Methodologies

  • The objective of the study was to ascertain if different intensities of physical exertion affect the plasma concentration of apelin in horses. Additionally, it aimed to determine if long-term regular training had an effect on resting blood apelin levels.
  • The study involved 20 purebred Arabian horses, divided into two groups. One group consisted of 10 racing horses aged 3 years and the second comprised of 10 horses ranging from 6 to 12 years, used in endurance rides.
  • Blood samples were collected from each horse during their resting period and after their respective physical activities. These plasma samples were then tested for concentrations of apelin and several parameters such as lactic acid, cortisol, uric acid, triacylglycerols, total plasma protein, and glucose.

Observations and Findings

  • The study found that racing training sessions led to significant reductions in plasma apelin concentrations.
  • For endurance horses, significant correlations were found between exercise-induced changes in apelin and cortisol, and apelin and uric acid concentrations.
  • The research concluded that the concentration of apelin in horse plasma decreases in response to short-term exercise, as opposed to endurance exercises.
  • It was also observed that the apelin concentration at rest was lower in horses that had been trained regularly for a longer time, compared to horses at the early stages of their training process.

Conclusion

  • The research provides crucial insights into the behavior of plasma apelin concentration in response to differing levels of physical exercise in horses.
  • These findings may have impacts on devising physical training sessions for horses since apelin plays a key role in the body’s energy metabolism process.

Cite This Article

APA
Kędzierski W, Cywińska A, Wawak T, Janczarek I, Wilk I, Kowalik S. (2019). Plasma Apelin Concentration in Exercised Horses: Preliminary Study. J Equine Vet Sci, 80, 16-19. https://doi.org/10.1016/j.jevs.2019.06.012

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 80
Pages: 16-19
PII: S0737-0806(19)30390-9

Researcher Affiliations

Kędzierski, Witold
  • Department of Biochemistry, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland.
Cywińska, Anna
  • Department of Pathology and Veterinary Diagnostic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, Warszawa, Poland.
Wawak, Tatiana
  • Department of Biochemistry, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland.
Janczarek, Iwona
  • Department of Horse Breeding and Use, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, Lublin, Poland.
Wilk, Izabela
  • Department of Horse Breeding and Use, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, Lublin, Poland.
Kowalik, Sylwester
  • Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland. Electronic address: sylwester.kowalik@up.lublin.pl.

MeSH Terms

  • Animals
  • Apelin
  • Energy Metabolism
  • Horses
  • Hydrocortisone
  • Physical Conditioning, Animal
  • Physical Exertion

Citations

This article has been cited 2 times.
  1. Soltani S, Beigrezaei S, Malekahmadi M, Clark CCT, Abdollahi S. Circulating levels of adropin and diabetes: a systematic review and meta-analysis of observational studies.. BMC Endocr Disord 2023 Apr 7;23(1):73.
    doi: 10.1186/s12902-023-01327-0pubmed: 37029398google scholar: lookup
  2. Kowalik S, Wiśniewska A, Kędzierski W, Janczarek I. Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses-Preliminary Study.. Animals (Basel) 2020 Dec 1;10(12).
    doi: 10.3390/ani10122268pubmed: 33271939google scholar: lookup