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[Population genetic analysis of the heritability of gutteral pouch tympany in Arabian purebred foals].

Abstract: The objective of the present study was to analyse the importance of the influences of the sex, inbreeding coefficient and the additive genetic contribution to the occurrence of guttural pouch tympany in Arabian foals. Horses affected by guttural pouch tympany were ascertained in the Clinic for Horses, School of Veterinary Medicine Hannover. The data comprised 27 Arabian purebred foals with guttural pouch tympany. Of these 27 animals 22 were patients of the Clinic for Horses between 1994 and 2001 and 5 Arabian foals were sampled on the studs. Information on the pedigrees of these patients allowed us to sort in the affected foals into four families with a total of 276 animals. Female foals were more often affected by guttural pouch tympany. The difference was 11.9% in favour of female foals. The size of the inbreeding coefficient was not important for the occurrence of guttural pouch tympany. The heritability estimate for the frequency of guttural pouch tympany using a threshold model was 0.49 +/- 0.28. This is the first report that could show a genetic component responsible for guttural pouch tympany in foals.
Publication Date: 2003-12-04 PubMed ID: 14650737
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  • English Abstract
  • Journal Article

Summary

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This study aims to analyze the influence of sex, inbreeding coefficient, and additive genetic contribution on the occurrence of guttural pouch tympany in Arabian foals, with results indicating a significant genetic component.

Research Objective

  • The study aimed to explore the significance of three variables: sex, an inbreeding coefficient, and the additive genetic contribution in relation to the prevalence of guttural pouch tympany, a condition that affects the upper respiratory tract, in Arabian purebred foals.

Data Collection

  • Data for the study was collected from the Clinic for Horses, School of Veterinary Medicine Hannover.
  • The sample consisted of 27 Arabian purebred foals affected by guttural pouch tympany, 22 of which were patients at the clinic from 1994 to 2001, while 5 were sampled from studs.
  • Pedigree information of these patients was recorded, enabling the researchers to categorise the affected foals into four distinct families comprising a total of 276 animals.

Results

  • Results demonstrated that female foals were more likely to be affected by guttural pouch tympany with a 11.9% differential.
  • The study found that the size of the inbreeding coefficient was not significant in terms of the occurrence of guttural pouch tympany.
  • The heritability of guttural pouch tympany was determined using a threshold model, which produced an estimate of 0.49 +/- 0.28.
  • This research pointed towards a notable genetic component in the prevalence of guttural pouch tympany in foals – the first such finding in this topic.

Cite This Article

APA
Blazyczek I, Hamann H, Ohnesorge B, Deegen E, Distl O. (2003). [Population genetic analysis of the heritability of gutteral pouch tympany in Arabian purebred foals]. Dtsch Tierarztl Wochenschr, 110(10), 417-419.

Publication

ISSN: 0341-6593
NlmUniqueID: 7706565
Country: Germany
Language: ger
Volume: 110
Issue: 10
Pages: 417-419

Researcher Affiliations

Blazyczek, I
  • Klinik für Pferde, Tierrztlichen Hochschule Hannover.
Hamann, H
    Ohnesorge, B
      Deegen, E
        Distl, O

          MeSH Terms

          • Animals
          • Eustachian Tube / pathology
          • Female
          • Horse Diseases / epidemiology
          • Horse Diseases / genetics
          • Horses
          • Inbreeding
          • Male
          • Models, Genetic
          • Pharyngeal Diseases / epidemiology
          • Pharyngeal Diseases / genetics
          • Pharyngeal Diseases / veterinary
          • Pharynx / pathology
          • Sex Factors