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Home / Equine Research Bank / New Microbes New Infect / Prevalence of zoonotic and non-zoonotic Rickettsia in horses...
New microbes and new infections2022; 51; 101068; doi: 10.1016/j.nmni.2022.101068

Prevalence of zoonotic and non-zoonotic Rickettsia in horses: A systematic review and meta-analysis.

Abstract: In a broad sense, are a group of microorganisms that can be transmitted mechanically or biologically to animals and humans. Rickettsioses are associated with hematic manifestations. Its prevalence in humans, dogs and other animals has been widely explored, but not in equine species. To determine the prevalence of infection in horses. A systematic review of the literature was carried out in five databases for the proportion of horses infected with , defined by molecular and immunological techniques. A meta-analysis was performed using a random-effects model to calculate the pooled prevalence and 95% confidence intervals (CI). The Cochran's Q test and the I statistic were used to assess the between-study-heterogeneity. The pooled prevalence of in equines was 37.0% (95% CI: 26.0%-47.0%), with significant heterogeneity among studies (I = 98.12%). In the subgroup analysis, the prevalence of in horses was found to be 24.0% (95%CI: 10.0%-41.0%) for IFI, 47.0% (95%CI: 30.0%-64.0%) for IFA, 14.0% (95%CI: 11.0%-17.0%) for IFAT and 39.0% (95%CI: 0.0%-95.0%) for PCR. There was a high prevalence of among horses, with some of the species being zoonotic, with their corresponding implications for humans, which increasingly are in close contact with equines, particularly horses and their ticks, posing a risk for spillover and transmission.
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Publication Date: 2022-12-17 PubMed ID: 36632173PubMed Central: PMC9827057DOI: 10.1016/j.nmni.2022.101068Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research aims to understand the prevalence of Rickettisa, a type of microorganism, in horses. The study shows a high prevalence of Rickettsia in horses, some of which can be transmitted to humans, particularly those in close contact with equines and their ticks.

Systematic Review and Meta-analysis

  • The research was carried out following a systematic approach, collecting and evaluating all available literature from five different databases. The selection criterion was based on studies reporting proportions of horses infected with Rickettsia.
  • The documents obtained were further analyzed using a meta-analysis, which is an advanced statistical technique that combines the results from individual studies to find a common outcome or effect.
  • The meta-analysis was performed using a random-effects model. This type of statistical model considers both the within-study variance and between-study variance, providing a more generalized result.

Risk Analysis and Prevalence

  • Results showed that the pooled prevalence (combined rate from all studies) of Rickettsia in equines was 37.0%, pointing towards a high presence of Rickettsia infection among horses.
  • The team also employed Cochran’s Q test and the I statistic to measure the level of variability among the individual studies included in the meta-analysis. A high I statistic (98.12%) indicated significant heterogeneity, meaning the study results varied greatly.

Subgroup Analysis and Implications

  • A subgroup analysis, conducted for more detailed insights, revealed the prevalence of Rickettsia in horses at different rates based on different diagnostic techniques. The prevalence varied from 14.0% to 47.0%, depending on the method used.
  • The study underlines that a substantial number of horses are infected with zoonotic Rickettsia species. Zoonotic refers to diseases that can be transmitted from animals to humans. This signifies a risk for humans, especially those in frequent contact with horses and their ticks, as they are susceptible to infection transmission.

Cite This Article

APA
Bonilla-Aldana DK, Castaño-Betancourt KJ, Ortega-Martínez JM, Ulloque-Badaracco JR, Hernandez-Bustamante EA, Benites-Zapata VA, Rodriguez-Morales AJ. (2022). Prevalence of zoonotic and non-zoonotic Rickettsia in horses: A systematic review and meta-analysis. New Microbes New Infect, 51, 101068. https://doi.org/10.1016/j.nmni.2022.101068

Publication

New microbes and new infections
ISSN: 2052-2975
NlmUniqueID: 101624750
Country: England
Language: English
Volume: 51
Pages: 101068
PII: 101068

Researcher Affiliations

Bonilla-Aldana, D Katterine
  • Research Unit, Universidad Continental, Huancayo, Peru.
  • Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) - Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia.
Castaño-Betancourt, Karen Johana
  • Faculty of Veterinary Medicine, Fundación Universitaria Autónoma de Las Américas - Institución Universitaria Visión de Las Américas, Pereira, Risaralda, Colombia.
Ortega-Martínez, Juan Manuel
  • Faculty of Veterinary Medicine, Fundación Universitaria Autónoma de Las Américas - Institución Universitaria Visión de Las Américas, Pereira, Risaralda, Colombia.
Ulloque-Badaracco, Juan R
  • Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Hernandez-Bustamante, Enrique A
  • Sociedad Científica de Estudiantes de Medicina de La Universidad Nacional de Trujillo, Trujillo, Peru.
  • Grupo Peruano de Investigación Epidemiológica, Unidad de Investigación para La Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.
Benites-Zapata, Vicente A
  • Grupo Peruano de Investigación Epidemiológica, Unidad de Investigación para La Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.
Rodriguez-Morales, Alfonso J
  • Faculty of Health Sciences, Universidad Científica Del Sur, Lima, Peru.
  • Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de Las Américas - Institución Universitaria Visión de Las Américas, Pereira, Risaralda, Colombia.
  • Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut P.O. Box 36, Lebanon.
  • Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) - Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia.

Conflict of Interest Statement

The authors declare no conflicts of interest.

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Citations

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