[Prospective assessment of circulatory sufficiency of the patients after 3F equine pericardial stentless bioprosthesis replacement].
Abstract: During years more and more advanced Technologies are used for treatment of severe aortic stenosis. One of them is equine pericardial stentless bioprothesis. Objective: the aim of the study was prospective assessment of circulatory sufficiency of the patients after 3F equine pericardial stentless bioprothesis replacement (ATS-Medtronic, Inc, Minneapolis, USA). Methods: Patients qualified to valve replacement were qualified to the study. The procedures were performed in general anesthesia and medial thoracothomy. The New York Heart Association (NYHA) scale was analyzed to estimate clinical results of the procedures. Results: 45 patients (10 women and 35 men) aged 23-78 (mean 54 (+/- SD 12.7) were included into the study. Patients were observed during one-year follow up (FU). At the baseline three pts had NYHA II stage, 35 - III and 7 - IV. There was no pts in NYHA I stage. After 3-6 months FU 34 pts were at NYHA I stage (79%) and 9 at NYHA II. After 11-14 FU 33 pts were at NYHA I (80.4%) and 8 NYHA II (19.5%). There was no pts at NYHA IV during 12 months FU (differences between observational periods statistically significant p < 0.001). Conclusions: During one-year FU after equine pericardial stentless bioprothesis implantation the improvement of NYHA grade was observed.
Publication Date: 2012-10-26 PubMed ID: 23094433
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- Evaluation Study
- Journal Article
Summary
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The research article discusses a study that evaluates the effectiveness of using an equine pericardial stentless bioprosthesis, a type of aortic valve replacement, on patients with aortic stenosis. The results indicated improvements in patients’ circulatory sufficiency after the procedure.
Objective and Methods
- The research aimed to assess the circulatory health of patients following a valve replacement using a 3F equine pericardial stentless bioprosthesis developed by ATS-Medtronic.
- The study used a prospective design, observing patients who were selected to undergo valve replacement.
- The replacement procedures were carried out under general anesthesia and involved medial thoracotomy, an invasive surgical procedure that accesses the chest cavity to expose the heart and its vessels.
- The study used the New York Heart Association (NYHA) functional classification system to determine the outcomes of the procedures. The NYHA grades range from I, showing no limitation of physical activities, to IV, which shows inability to perform any physical activity without discomfort.
Study Results
- A total of 45 patients, made up of 10 women and 35 men aged between 23 and 78, were evaluated in the study.
- They were observed for 12 months after undergoing the replacement procedure. At the start of the study, three patients were classified under NYHA grade II, 35 under grade III, and seven under grade IV. No patients were at the NYHA grade I.
- After 3-6 months, 79% of the patients moved to NYHA grade I and the rest were in grade II. By the 11-14 months follow-up, 80.4% were at NYHA grade I and 19.5% were at NYHA grade II.
- No patients were observed to be at NYHA grade IV throughout the 12 months follow-up period.
Conclusions
- The results of the study indicate significant improvement in the NYHA grades of patients following the implantation of the equine pericardial stentless bioprosthesis.
- This suggests that this type of valve replacement could beneficially impact the circulatory health of patients with severe aortic stenosis.
Cite This Article
APA
Bartuś K, Sadowski J, Kapelak B, Wierzbicki K, Myć J, Bartuś S, Oleś K, Konstanty-Kalandyk J, Filip G.
(2012).
[Prospective assessment of circulatory sufficiency of the patients after 3F equine pericardial stentless bioprosthesis replacement].
Przegl Lek, 69(6), 229-232.
Publication
Researcher Affiliations
- Klinika Chirurgii Serca Naczyń i Transplantologii Collegium Medicum, Uniwersytetu Jagiellońskiego, Kraków. krzysztofbartus@gmail.com
MeSH Terms
- Adult
- Aged
- Animals
- Aortic Valve / surgery
- Aortic Valve Stenosis / therapy
- Bioprosthesis
- Female
- Follow-Up Studies
- Heart Valve Prosthesis
- Hemodynamics
- Horses
- Humans
- Male
- Middle Aged
- Prospective Studies
- Treatment Outcome
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