Purulent pericarditis and pneumonia caused by Streptococcus equi subsp. zooepidemicus.
Abstract: Purulent pericarditis is a life-threatening disease that usually manifests following bacteraemia or through spreading from an intrathoracic focus. Only a few cases of this disease have been reported with Lancefield group C streptococci as aetiological agents, and the primary focus in these infections remains unknown. We report a case of purulent pericarditis with septic and cardiogenic shock, caused by Streptococcus equi subsp. zooepidemicus (group C) in a 51-year-old patient. The pathogen was possibly contracted through contact with horses. Most probably, it caused initially pneumonia before spreading to the pericardium, either directly or via the bloodstream. A combined therapeutic approach, consisting of antibiotic therapy and repeated pericardial drainage, was necessary to ensure a clinical cure. After discharge, long-term follow-up for development of constrictive pericarditis is considered mandatory.
Publication Date: 2013-11-15 PubMed ID: 24243287DOI: 10.1099/jmm.0.066290-0Google Scholar: Lookup
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Summary
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This research is about a rare and severe case of purulent pericarditis caused by Streptococcus equi subsp. zooepidemicus, a bacteria commonly found in horses, which likely started as pneumonia in a 51-year-old patient.
About the Study
- The researchers present a case study of a 51-year-old patient with purulent pericarditis, a severe and life-threatening disease usually caused by bacteria in the bloodstream or spread from an infection in the chest area.
- The infection in this case was caused by Streptococcus equi subsp. zooepidemicus, a bacteria typically found in horses, placing it in the Lancefield group C streptococci. This group of bacterium is not commonly associated with purulent pericarditis, with very few cases reported globally.
Case Progression
- This particular case is unique because the researchers suspect the initial infection commenced as pneumonia, then spread to the pericardium, the membrane around the heart, either directly or through the bloodstream.
- The patient likely contracted the pathogen through contact with horses, further highlighting the zoonotic potential of the bacteria (the ability to jump from animals to humans).
Treatment and Aftercare
- The treatment for this patient included a combination of antibiotics to combat the infection and repeated pericardial drainage to remove the accumulated pus around the heart. This multi-pronged approach was necessary to ensure a complete clinical cure.
- The researchers also emphasize the importance of long-term monitoring after the patient’s discharge. This is due to the potential development of constrictive pericarditis, a condition where the pericardium becomes thickened and scarred, potentially leading to severe heart complications.
Significance of the Research
- This study offers valuable information about a rare presentation of purulent pericarditis caused by a zoonotic pathogen, providing essential clinical insights about its diagnosis and management.
- It also highlights the importance of considering zoonotic sources in the diagnosis of rare infections, and the need for comprehensive treatment and long-term follow-up in severe cases of purulent pericarditis.
Cite This Article
APA
Held J, Schmitz R, van der Linden M, Nührenberg T, Häcker G, Neumann FJ.
(2013).
Purulent pericarditis and pneumonia caused by Streptococcus equi subsp. zooepidemicus.
J Med Microbiol, 63(Pt 2), 313-316.
https://doi.org/10.1099/jmm.0.066290-0 Publication
Researcher Affiliations
- Institute of Medical Microbiology and Hygiene, University Medical Centre Freiburg, 79104 Freiburg, Germany.
- Department of Clinical Cardiology I, Heart Center Freiburg University, 79189 Bad Krozingen, Germany.
- National Reference Center for Streptococci, Department of Medical Microbiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
- Department of Clinical Cardiology I, Heart Center Freiburg University, 79189 Bad Krozingen, Germany.
- Institute of Medical Microbiology and Hygiene, University Medical Centre Freiburg, 79104 Freiburg, Germany.
- Department of Clinical Cardiology I, Heart Center Freiburg University, 79189 Bad Krozingen, Germany.
MeSH Terms
- Anti-Bacterial Agents / therapeutic use
- Drainage
- Echocardiography
- Humans
- Male
- Middle Aged
- Pericarditis / complications
- Pericarditis / diagnosis
- Pericarditis / microbiology
- Pericarditis / therapy
- Pneumonia, Bacterial / complications
- Pneumonia, Bacterial / diagnosis
- Pneumonia, Bacterial / microbiology
- Pneumonia, Bacterial / therapy
- Radiography, Thoracic
- Shock, Septic / complications
- Shock, Septic / diagnosis
- Shock, Septic / microbiology
- Shock, Septic / therapy
- Streptococcal Infections / diagnosis
- Streptococcal Infections / microbiology
- Streptococcal Infections / therapy
- Streptococcus
- Streptococcus equi / isolation & purification
- Tomography, X-Ray Computed
Citations
This article has been cited 5 times.- Azpiroz MF, Burger N, Mazza M, Rodríguez G, Camou T, García Gabarrot G. Characterization of Streptococcus equi subsp. zooepidemicus isolates containing lnuB gene responsible for the L phenotype.. PLoS One 2023;18(4):e0284869.
- Shikina EV, Kovalevsky RA, Shirkovskaya AI, Toukach PV. Prospective bacterial and fungal sources of hyaluronic acid: A review.. Comput Struct Biotechnol J 2022;20:6214-6236.
- Waśniewska-Włodarczyk A, Pepaś R, Janowicz R, Konopka W. Streptococcus equi subsp. equi in Retropharyngeal Abscess: Case Report and Review of Literature.. Microorganisms 2022 Oct 14;10(10).
- Kittang BR, Pettersen VK, Oppegaard O, Skutlaberg DH, Dale H, Wiker HG, Skrede S. Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer.. BMC Infect Dis 2017 Feb 15;17(1):147.
- Madžar D, Hagge M, Möller S, Regensburger M, Lee DH, Schwab S, Jantsch J. Endogenous endophthalmitis complicating Streptococcus equi subspecies zooepidemicus meningitis: a case report.. BMC Res Notes 2015 May 5;8:184.
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