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Equine veterinary journal2022; 55(1); 24-32; doi: 10.1111/evj.13562

Radiographic changes of the proximal third metatarsal bone do not predict presence or severity of proximal suspensory desmopathy in a predominately Quarter Horse population.

Abstract: Comparison of radiography to magnetic resonance imaging (MRI) can help objectively assess the value and limitations of radiographs in orthopaedic disease processes. The tarsus and proximal suspensory origin of the metatarsus are commonly imaged regions for lameness. The knowledge gained by comparison between imaging modalities will aid in improving accuracy of radiographic interpretation. Objective: To compare the radiographic and MRI findings of the proximal third metatarsal bone (MTIII) and proximal suspensory ligament using MRI as the gold standard. Methods: Retrospective observational study. Methods: Single hindlimbs of 35 horses with radiographic and high-field (3Tesla (3T)) MRI studies were blindly evaluated by two board-certified veterinary radiologists and a radiology resident. Severity and location of the following parameters were assessed: radiographic MTIII sclerosis and lucent regions, MRI endosteal metatarsal sclerosis and bone marrow lesions, plantar cortical proliferation and resorption, and proximal suspensory desmopathy (PSD). Results: Radiographic osseous changes of MTIII were identified in 54% of limbs, whereas 40% limbs had osseous changes on MRI: 43% of limbs had PSD on MRI. No significant association was found between the presence of radiographic changes in MTIII and PSD on MRI (P = .7). A statistically significant association and positive correlation was found between the severity of radiographic changes and MTIII plantar cortical proliferation and resorption on MRI (P = .01). Conclusions: Retrospective study with no histopathology. Ability to correlate findings with lameness was limited by the lack of standardised time intervals between onset of lameness, diagnostic analgesia and advanced imaging. Conclusions: Radiographic bony changes of proximal MTIII do not reliably predict presence or severity of PSD but are associated with osseous changes at the proximal MTIII. The presence of radiographic changes should warrant additional diagnostics in the region prior to making conclusions about the presence or absence of PSD. Unassigned: La comparaison de la radiographie avec l'imagerie par résonance magnétique (IRM) peut assister dans l’évaluation objective de la valeur et des limites des radiographies pour les processus pathologiques orthopédiques. Objective: Comparer les trouvailles radiographiques et d’IRM du métatarsien principal proximal (MTIII) et de la portion proximale du ligament suspenseur du boulet, en utilisant l’IRM comme référence. TYPE D’ÉTUDE: Étude de observationnelle rétrospective. MÉTHODES: Les images radiographiques et d’IRM à haut champ (3 Tesla (3T)) d'un seul membre postérieur chez 35 chevaux ont été évalués à l'aveugle par deux radiologistes vétérinaires diplômés et un résident en radiologie. La sévérité et localisation des paramètres suivants ont été documentés : sclérose et régions lytiques radiographiques du MTIII, sclérose métatarsienne de l'endostéum à l’IRM et lésions de la moelle osseuse, prolifération et résorption plantaire corticale et desmopathie du ligament suspenseur du boulet (DLSB). RÉSULTATS: Des changements radiographiques osseux du MTIII ont été identifiés sur 54 % des membres contre 40% des membres ayant des changements osseux à l’IRM. 43% des membres avaient une DLSB à l’IRM. Aucune association significative n'a pu être identifiée entre la présence de changements radiographiques du MTIII et DLSB à l’IRM (P = 0.7). Une association statistiquement significative et une corrélation positive a été identifiée entre la sévérité des changements radiographiques et la résorption/prolifération plantaires corticales du MTIII à l’IRM (P = 0.01). Unassigned: Étude rétrospective sans histopathologie. La possibilité de corréler les données de l'examen de boiterie a été limitée par le manque d'intervalle de temps standardisés entre l'apparition de la boiterie, l'analgésie diagnostique et l'imagerie avancée. Conclusions: Ces trouvailles démontrent que les changements osseux radiographiques du MTIII proximal ne peuvent prédirent de façon fiable la présence ni la sévérité de DLSB, mais ils sont par contre associés aux changements osseux du MTIII proximal à l'IRM. La présence de changements radiographiques justifie l'utilisation de méthodes diagnostiques additionnelles du MTIII proximal avant de conclure sur la présence ou l'absence de DLSB.
Publication Date: 2022-02-11 PubMed ID: 35092318DOI: 10.1111/evj.13562Google Scholar: Lookup
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  • Observational Study
  • Veterinary
  • Journal Article

Summary

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The research article deals with comparing the use of radiography and magnetic resonance imaging (MRI) in assessing orthopaedic disease processes in horses. Specifically, the study focuses on whether radiographic changes in the proximal third metatarsal bone (MTIII) can predict the presence or severity of proximal suspensory desmopathy (PSD), a common lameness condition in horses.

Methods

  • The study involved the retrospective review of single hindlimbs in 35 horses that have both radiographic and high-field MRI studies.
  • These studies were evaluated by two board-certified veterinary radiologists and a radiology resident.
  • The severity and location of several parameters were assessed, such as radiographic MTIII sclerosis, and lucent regions, MRI endosteal metatarsal sclerosis, bone marrow lesions, plantar cortical proliferation and resorption, and proximal suspensory desmopathy (PSD).

Results

  • Radiographic changes of MTIII were identified in 54% of the limbs, whereas 40% of limbs showed changes on MRI. Also, 43% of limbs showed PSD on MRI.
  • No significant association was found between the presence of radiographic changes in MTIII and PSD on MRI.
  • A statistically significant association and positive correlation were found between the severity of radiographic changes and MTIII plantar cortical proliferation and resorption on MRI.

Conclusions

  • The study was limited by the lack of standardised time intervals between the onset of lameness, diagnostic analgesia, and advanced imaging. Also, it should be noted that the study was retrospective and didn’t involve histopathology.
  • The researchers concluded that radiographic changes of the proximal MTIII do not reliably predict the presence or severity of PSD. However, these changes are associated with osseous changes at the proximal MTIII.
  • The presence of radiographic changes should prompt additional diagnostics in the region before making conclusions about the presence or absence of PSD.

Cite This Article

APA
Hinkle FE, Selberg KT, Frisbie DD, Barrett MF. (2022). Radiographic changes of the proximal third metatarsal bone do not predict presence or severity of proximal suspensory desmopathy in a predominately Quarter Horse population. Equine Vet J, 55(1), 24-32. https://doi.org/10.1111/evj.13562

Publication

ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 55
Issue: 1
Pages: 24-32

Researcher Affiliations

Hinkle, Frances E
  • Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Selberg, Kurt T
  • Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.
Frisbie, David D
  • Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Barrett, Myra F
  • Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.

MeSH Terms

  • Horses
  • Animals
  • Metatarsal Bones / diagnostic imaging
  • Metatarsal Bones / pathology
  • Lameness, Animal / diagnostic imaging
  • Horse Diseases / pathology
  • Retrospective Studies
  • Sclerosis / pathology
  • Sclerosis / veterinary
  • Magnetic Resonance Imaging / veterinary
  • Magnetic Resonance Imaging / methods

References

This article includes 15 references
  1. Contino EK, King MR, Valdés-Martínez A. In vivo diffusion characteristics following perineural injection of the deep branch of the lateral plantar nerve with mepivacaine or iohexol in horses.. Equine Vet J 2015;47:230-4.
  2. Dyson SJ. Proximal metacarpal and metatarsal pain: a diagnostic challenge.. Equine Vet Educ 2003;15:134-8.
  3. Dyson SJ, Romero JM. An investigation of injection techniques for local analgesia of the equine distal tarsus and proximal metatarsus.. Equine Vet J 1993;25:30-5.
  4. Labens R, Schramme MC, Robertson ID, Thrall DE, Redding WR. Clinical, magnetic resonance, and sonographic imaging findings in horses with proximal plantar metatarsal pain.. Vet Radiol Ultrasound 2010;51:11-8.
  5. Barrett MF, Selberg KT, Johnson SA, Hersman J, Frisbie DD. High field magnetic resonance imaging contributes to diagnosis of equine distal tarsus and proximal metatarsus lesions: 103 horses.. Vet Radiol Ultrasound 2018;59:587-96.
  6. Hinnigan G, Milner P, Talbot A, Singer E. Is anaesthesia of the deep branch of the lateral plantar nerve specific for the diagnosis of proximal metatarsal pain in the horse?. Vet Comp Orthop Traumatol 2014;27:351-7.
  7. Brokken MT, Schneider RK, Sampson SN, Tucker RL, Gavin PR, Ho CP. Magnetic resonance imaging features of proximal metacarpal and metatarsal injuries in the horse.. Vet Radiol Ultrasound 2007;48:507-17.
  8. Dyson S. Proximal suspensory desmitis: clinical, ultrasonographic and radiographic features.. Equine Vet J 1991;23:25-31.
  9. Dyson S. Proximal suspensory desmitis in the hindlimb: 42 cases.. Br Vet J 1994;150:279-91.
  10. Dyson S. Diagnosis and management of common suspensory lesions in the forelimbs and hindlimbs of sport horses.. Clinical Techniques in Equine Practice 2007;6:179-88.
  11. Dyson S, Murray R, Pinilla M-J. Proximal suspensory desmopathy in hindlimbs: a correlative clinical, ultrasonographic, gross post mortem and histological study.. Equine Vet J 2017;49:65-72.
  12. Dyson SJ, Weekes JS, Murray RC. Scintigraphic evaluation of the proximal metacarpal and metatarsal regions of horses with proximal suspensory desmitis.. Vet Radiol Ultrasound 2007;48:78-85.
  13. Trump M, Siegenthaler E, Kircher PR, Fürst A, Theiss F. Comparison of radiographic changes of the proximal third metacarpal and metatarsal bones in horses with and without proximal suspensory desmitis.. Pferdeheilkunde 2014;30:671-6.
  14. Weekes JS, Murray RC, Dyson SJ. Scintigraphic evaluation of the proximal metacarpal and metatarsal regions in clinically sound horses.. Vet Radiol Ultrasound 2006;47:409-16.
  15. Claudepierre P, Voisin M-C. The entheses: histology, pathology, and pathophysiology.. Joint Bone Spine 2005;72:32-7.

Citations

This article has been cited 2 times.
  1. Guest DJ, Birch HL, Thorpe CT. A review of the equine suspensory ligament: Injury prone yet understudied. Equine Vet J 2025 Sep;57(5):1167-1182.
    doi: 10.1111/evj.14447pubmed: 39604165google scholar: lookup
  2. Dancot M, Joostens Z, Audigié F, Busoni V. The plantar proximal cortex of the third metatarsal bone shows raised longitudinal ridges at the suspensory ligament enthesis in normal equine isolated limbs - a radiographic, computed tomography, and MRI study. Front Vet Sci 2023;10:1265116.
    doi: 10.3389/fvets.2023.1265116pubmed: 38033644google scholar: lookup