Reactive mesothelial hyperplasia associated with chronic peritonitis in a 20-year-old Quarter horse.
Abstract: A 20-year-old gelding was diagnosed with peritonitis and severe reactive mesothelial hyperplasia. Exploratory laparotomy findings were suggestive of a neoplastic etiology; however, additional diagnostics ruled this out and the horse made a full recovery. This report demonstrates the difficulty and value of differentiating between reactive and neoplastic mesothelial processes. Une péritonite et l’hyperplasie mésothéliale réactive grave ont été diagnostiquées chez un hongre âgé de 20 ans. Les résultats d’une laparatomie exploratoire ont suggéré une étiologie néoplasique. Cependant, des diagnostics additionnels ont éliminé cette possibilité et le cheval s’est complètement rétabli. Ce rapport démontre la difficulté et la pertinence de différencier entre les processus mésothéliaux réactif et néoplasique.(Traduit par Isabelle Vallières).
Publication Date: 2016-05-07 PubMed ID: 27152035PubMed Central: PMC4827738
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Summary
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This research article is a case study of a 20-year-old gelding horse diagnosed with peritonitis and severe reactive mesothelial hyperplasia, initially suspected to be due to a cancerous condition, but later ruled out.
Understanding Mesothelial Hyperplasia and Peritonitis
- Mesothelial hyperplasia is a condition where the mesothelial cells grown in number excessively. Mesothelial cells line the serous cavities of the body (like chest, abdomen).
- When these cells react to inflammation or injury, the condition is known as reactive mesothelial hyperplasia.
- Peritonitis refers to inflammation of the membrane that lines the inner wall of the abdomen and covers most of the abdominal organs.
Initial Diagnosis and Investigation
- The 20-year-old gelding horse was found to be suffering from both of these conditions.
- An exploratory laparotomy (surgical procedure to examine the abdominal organs) was conducted, which suggested the possible presence of a neoplastic condition, meaning that the condition was suspected to be due to cancer or a tumour.
Additional Diagnostics and Recovery
- However, further diagnoses were undertaken that ruled out the neoplastic etiology, meaning that cancer or a tumour was not the cause of the horse’s condition.
- The horse eventually made a complete recovery from its condition.
Conclusion and Observations
- Through this case study, the researchers highlight the difficulty in distinguishing between reactive and neoplastic mesothelial processes.
- Despite the initial suspicion of a cancerous condition, the horse’s recovery after ruling out a neoplastic cause demonstrates the importance of thorough diagnostic procedures in determining the appropriate treatment plan.
- This case underscores the value of differentiating between reactive and neoplastic mesothelial processes in the context of veterinary medicine.
Cite This Article
APA
Hoon-Hanks LL, Rout ED, Vap LM, Aboellail TA, Hassel DM, Nout-Lomas YS.
(2016).
Reactive mesothelial hyperplasia associated with chronic peritonitis in a 20-year-old Quarter horse.
Can Vet J, 57(5), 492-496.
Publication
Researcher Affiliations
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
- Department of Microbiology, Immunology and Pathology (Hoon-Hanks, Rout, Vap, Aboellail) and Department of Clinical Sciences (Hassel, Nout-Lomas), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1601 Campus Delivery, Fort Collins, Colorado 80523-1601, USA.
MeSH Terms
- Animals
- Diagnosis, Differential
- Epithelium / pathology
- Horse Diseases / diagnosis
- Horse Diseases / etiology
- Horses
- Hyperplasia / diagnosis
- Hyperplasia / etiology
- Hyperplasia / pathology
- Hyperplasia / veterinary
- Male
- Peritonitis / complications
- Peritonitis / diagnosis
- Peritonitis / veterinary
References
This article includes 17 references
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Citations
This article has been cited 2 times.- Plesker R, Köhler K, von Gerlach S, Boller K, Vogt M, Feder IS. Reactive mesothelial hyperplasia mimicking mesothelioma in an African green monkey (Chlorocebus aethiops). Primate Biol 2020;7(1):5-12.
- Dusick AF, Bach JF, Liao PT, Hartmann FA. Growth of adenocarcinoma from canine pleural fluid on aerobic bacterial culture. J Vet Diagn Invest 2020 Jan;32(1):156-158.
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