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Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2022; 33(2); 217-222; doi: 10.1111/vec.13274

Red cell distribution width values and red cell distribution width-to-platelet ratio in Thoroughbred foals in the first 24 hours of life.

Abstract: To report red cell distribution width (RDW) values, to calculate RDW-to-platelet ratio (RPR), and to investigate a possible correlation of RDW and RPR index values in neonatal foals classified as healthy or at risk based on clinical information from a population of foals up to 24 hours of life. Methods: Retrospective study conducted from records and CBCs of foals born between June and November from 2018 to 2020 foaling seasons. Methods: Breeding farm. Methods: Three hundred and nine neonatal full-term Thoroughbred foals. Methods: None. Results: Foals were evaluated by a veterinarian within 15 minutes after birth, and a blood sample was collected within 24 hours of life. Based on clinical information, 88 of 309 foals (28.4%) were considered at risk of perinatal disease, and 201 were healthy. Mean gestational age for the foals was 346.3 ± 9.7 days. RDW values did not differ between groups. Gestational length demonstrated to have a negative correlation with RDW (r = -0.156, P = 0.005) and mean corpuscular volume (r = -0.135, P = 0.01), indicating a link of these variables to foal maturity. RPR index was higher for at-risk (0.073 ± 0.018) than for healthy foals (0.068 ± 0.014, P = 0.01). Conclusions: RPR might be a promising early indicator of disease for the field triage of neonatal foals.
© 2022 The Authors. Journal of Veterinary Emergency and Critical Care published by Wiley Periodicals LLC on behalf of Veterinary Emergency and Critical Care Society.
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Publication Date: 2022-12-20 PubMed ID: 36537889DOI: 10.1111/vec.13274Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research investigates the red cell distribution width (RDW) and RDW-to-platelet ratio (RPR) in Thoroughbred neonatal foals within the first 24 hours of their life. The study indicates that the RPR could serve as a promising early disease indicator in foals, and it found a noteworthy correlation between gestational length, RDW, and mean corpuscular volume.

Objective of the Study

  • The primary purpose of the research was to calculate and analyze the RDW and the RPR in Thoroughbred foals within the first 24 hours of their life.
  • The study aimed at finding a possible relationship between the RDW and RPR index values in neonatal foals, classifying them as either healthy or at risk based on clinical information.

Methodology

  • The retrospective study used records and Complete Blood Counts (CBCs) of 309 newborn full-term Thoroughbred foals born between June and November across the foaling seasons of 2018 to 2020.
  • Every foal was evaluated by a veterinarian within 15 minutes after birth, and blood samples were taken within 24 hours.

Results

  • Of the 309 foals taken into the study, it was clinically determined that 88 foals (28.4%) were at risk of perinatal disease while 201 were healthy.
  • The average gestational age for the foals was found to be approximately 346.3 days.
  • No significant difference in RDW values was observed between the groups.
  • However, a negative correlation was evident between the gestational length and both the RDW and mean corpuscular volume, suggesting a connection to foal maturity.
  • The RPR index for at-risk foals was higher than that of the healthy ones.

Conclusion

  • The study concluded that the RDW-to-platelet ratio (RPR) could act as a useful early indicator of disease in neonatal foals. This finding could drastically improve the field triage and early disease detection in newborn foals.

Cite This Article

APA
Scalco R, Aleman M, Nogueira CEW, Freitas NB, Curcio BR. (2022). Red cell distribution width values and red cell distribution width-to-platelet ratio in Thoroughbred foals in the first 24 hours of life. J Vet Emerg Crit Care (San Antonio), 33(2), 217-222. https://doi.org/10.1111/vec.13274

Publication

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
NlmUniqueID: 101152804
Country: United States
Language: English
Volume: 33
Issue: 2
Pages: 217-222

Researcher Affiliations

Scalco, Rebeca
  • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
  • Departamento de Clínicas Veterinária, Faculdade de Medicina Veterinária, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Aleman, Monica
  • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Nogueira, Carlos E W
  • Departamento de Clínicas Veterinária, Faculdade de Medicina Veterinária, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Freitas, Natalia B
  • Departamento de Clínicas Veterinária, Faculdade de Medicina Veterinária, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Curcio, Bruna R
  • Departamento de Clínicas Veterinária, Faculdade de Medicina Veterinária, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil.

MeSH Terms

  • Pregnancy
  • Female
  • Animals
  • Horses
  • Erythrocyte Indices / veterinary
  • Retrospective Studies
  • Seasons

Grant Funding

  • CAPES (Coordenau00e7u00e3o de Aperfeiu00e7oamento de Pessoal de Nu00edvel Superior)
  • CNPQ (Conselho Nacional de Desenvolvimento Cientu00edfico e Tecnolu00f3gico)
  • Equine and Comparative Neurology Research Group - UC Davis

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Citations

This article has been cited 2 times.
  1. Scalco R, de Oliveira GN, da Rosa Curcio B, Wooten M, Magdesian KG, Hidai ST, Pandit P, Aleman M. Red blood cell distribution width to platelet ratio in neonatal foals with sepsis. J Vet Intern Med 2023 Jul-Aug;37(4):1552-1560.
    doi: 10.1111/jvim.16793pubmed: 37306395google scholar: lookup
  2. Davias C, Mendoza FJ, De Las Heras A, Gonzalez-De-Cara C, Buzon-Cuevas A, Perez-Ecija A. Hematologic Ratios in Donkeys: Reference Intervals and Response to Experimentally Induced Endotoxemia. Animals (Basel) 2025 Aug 4;15(15).
    doi: 10.3390/ani15152272pubmed: 40805061google scholar: lookup
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