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BMC veterinary research2022; 18(1); 414; doi: 10.1186/s12917-022-03512-0

Relationship between estrus endometrial edema and progesterone production in pregnant mares two weeks after ovulation.

Abstract: Progesterone plays a crucial role in the maintenance of pregnancy from conception to about 100-120 days of gestation when placenta becomes the main source of gestagens. The aim of the study was to test progesterone concentration 14 days after ovulation in pregnant mares and relate it to peak estral endometrial edema and the presence of intrauterine fluid (IUF) after artificial insemination (AI), the number of treatments against IUF, and the time from AI to the day when the uterus was found free of fluid. Results: Mares were divided into two groups: group A (n = 13; age 10.8 ± 4.5 years) in which a normal embryonic vesicle with a diameter ≥ 14 mm and a corpus luteum with a diameter ≥ 15 mm were found 14 days after ovulation, and group B (n = 22; age 9.4 ± 4 .0 years) in which 14 days after ovulation, a small (< 15 mm) corpus luteum and/or a small embryonic vesicle was observed (diameter < 14 mm). Mares from group A had a significantly higher progesterone concentrations at 14 days after ovulation compared with group B mares. The presence of IUF, the number of treatments against IUF, and the time from AI to the day when uterus was found free of fluid did not affect progesterone concentration measured 14 days after ovulation. In group B, a significant correlation was found between progesterone concentration measured 14 days after ovulation and endometrial edema evaluated during estrus. Conclusions: In some cases poor development of endometrial edema during estrus can be associated with lower progesterone production 14 days after ovulation. Nevertheless, scientific explanation for this finding cannot be given based on our study.
© 2022. The Author(s).
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Publication Date: 2022-11-21 PubMed ID: 36414934PubMed Central: PMC9680132DOI: 10.1186/s12917-022-03512-0Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research studies the link between the level of progesterone, an important hormone in pregnancy, two weeks after ovulation and the status of endometrial edema (swelling of the uterine lining) in pregnant horses. The findings show that, in some cases, poor development of endometrial edema during estrus (heat cycle) could be linked to lower progesterone production two weeks after ovulation.

Objective of the Study

  • The aim of this research is to analyze the progesterone level in pregnant mares 14 days after ovulation and its relationship with peak estral endometrial edema and the presence of intrauterine fluid (IUF) post-artificial insemination.
  • It also aims to study the effect of the number of treatments against IUF and the time passed between artificial insemination (AI) and the day when no fluid is found in the uterus.

Methods and Groups in the Study

  • The mares were divided into two groups. Group A (13 mares with an average age of nearly 11 years) had normal-sized embryonic vesicles and corpus lutea 14 days after ovulation.
  • The second group, Group B (22 mares with an average age of approximately 9 years), had small corpus lutea and/or embryonic vesicles at the 14-day post-ovulation mark.

Findings from the Study

  • The researchers found that the mares in Group A had significantly higher progesterone concentrations 14 days after ovulation compared to Group B.
  • The presence of IUF, the number of treatments against IUF, and the time from AI to the day when no fluid was found in the uterus did not significantly affect the progesterone concentration 14 days post-ovulation.
  • For Group B mares, there was a significant correlation between the progesterone concentration 14 days after ovulation and endometrial edema assessed during estrus.

Conclusion of the Study

  • The study concludes that in some instances, a poor development of endometrial edema during the heat cycle can be linked with lower progesterone production 14 days after ovulation.
  • However, the study acknowledges that a scientific explanation for this finding could not be provided based on the conducted research.

Cite This Article

APA
Grabowska A, Kozdrowski R. (2022). Relationship between estrus endometrial edema and progesterone production in pregnant mares two weeks after ovulation. BMC Vet Res, 18(1), 414. https://doi.org/10.1186/s12917-022-03512-0

Publication

BMC veterinary research
ISSN: 1746-6148
NlmUniqueID: 101249759
Country: England
Language: English
Volume: 18
Issue: 1
Pages: 414

Researcher Affiliations

Grabowska, Anna
  • Anawet Sp. Z O.O., Ul. Spółdzielcza 3, 62-800, Kalisz, Poland.
Kozdrowski, Roland
  • Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Toruń, Poland. roland.kozdrowski@umk.pl.

MeSH Terms

  • Pregnancy
  • Horses
  • Female
  • Animals
  • Progesterone
  • Estrus
  • Ovulation
  • Insemination, Artificial / veterinary
  • Edema / veterinary

Conflict of Interest Statement

The authors have no conflict of interest to declare.

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Citations

This article has been cited 1 times.
  1. Newcombe JR, Cuervo-Arango J, Wilsher S. The Timing of the Maternal Recognition of Pregnancy Is Specific to Individual Mares. Animals (Basel) 2023 May 22;13(10).
    doi: 10.3390/ani13101718pubmed: 37238148google scholar: lookup
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